Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.

Chen, Haotian; Yang, Xiaokun; Gao, Yushan; Jiang, Huili; Guo, Mengwei; Zhou, Yingyi; Li, Chenlu; Tan, Yunxiang; Zhang, Yang; Xue, Weiguo

Chen, Haotian; Yang, Xiaokun; Gao, Yushan; Jiang, Huili; Guo, Mengwei; Zhou, Yingyi; Li, Chenlu; Tan, Yunxiang; Zhang, Yang; Xue, Weiguo.

Afiliação

Chen H; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Yang X; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Gao Y; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Jiang H; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Guo M; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Zhou Y; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Li C; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Tan Y; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 510405, China.
Zhang Y; Guangshui City Hospital of Traditional Chinese Medicine, 432700, China.
Xue W; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China. Electronic address: snowmanxue@126.com.

Brain Res ; 1823: 148683, 2024 01 15.

Article em En | MEDLINE | ID: mdl-37992796

Assuntos

Doença de Alzheimer; Disfunção Cognitiva; Eletroacupuntura; Animais; Masculino; Camundongos; Doença de Alzheimer/terapia; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Disfunção Cognitiva/terapia; Disfunção Cognitiva/metabolismo; Modelos Animais de Doenças; Hipocampo/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Transgênicos

Palavras-chave

APP/PS1 mice; Alzheimer's disease; Autophagy-lysosomal pathway; Electroacupuncture; Transcription factor EB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Eletroacupuntura / Doença de Alzheimer / Disfunção Cognitiva Limite: Animals Idioma: En Revista: Brain Res Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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