Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR-124/CILP/TGF-ß.

Liu, Yi; Xue, Mintao; Han, Yaguang; Li, Yucai; Xiao, Bing; Wang, Weiheng; Yu, Jiangming; Ye, Xiaojian

Liu, Yi; Xue, Mintao; Han, Yaguang; Li, Yucai; Xiao, Bing; Wang, Weiheng; Yu, Jiangming; Ye, Xiaojian.

Afiliação

Liu Y; Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai People's Republic of China.
Xue M; Department of Orthopedics Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai People's Republic of China.
Han Y; Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai People's Republic of China.
Li Y; Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai People's Republic of China.
Xiao B; Department of Orthopedics Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai People's Republic of China.
Wang W; Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai People's Republic of China.
Yu J; Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai People's Republic of China.
Ye X; Department of Orthopedics Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai People's Republic of China.

Bioeng Transl Med ; 8(6): e10500, 2023 Nov.

Article em En | MEDLINE | ID: mdl-38023721

Palavras-chave

M2c polarization; cartilage intermediate layer protein; exosomes; intervertebral disc degeneration; macrophages; miRNAs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Bioeng Transl Med Ano de publicação: 2023 Tipo de documento: Article