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Mitochondrial targeting derivatives of honokiol enhanced selective antitumor activity in NCI-H446 cells and decreased in vivo toxicity in Caenorhabditis elegans.
Miao, Huicong; Cui, Wenbo; Zhang, Tao; Zhang, Yue; Zhang, Jiaozhen; Lou, Hongxiang; Fan, Peihong.
Afiliação
  • Miao H; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China.
  • Cui W; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China.
  • Zhang T; Shandong Provincial Key Laboratory of Neuroprotective Drugs, Shandong Qidu Pharmaceutical Research Institute, Zibo 255400, PR China.
  • Zhang Y; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China.
  • Zhang J; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China.
  • Lou H; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China. Electronic address: louhongxiang@sdu.edu.cn.
  • Fan P; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, PR China. Electronic address: fanpeihong@sdu.edu.cn.
Eur J Med Chem ; 264: 115996, 2024 Jan 15.
Article em En | MEDLINE | ID: mdl-38086195
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lignanas / Antineoplásicos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lignanas / Antineoplásicos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article