Retinopathy Associated With Ritonavir Treatment for HIV Infection: A Case Series Reappraisal in the COVID-19 Era.
J Vitreoretin Dis
; 8(1): 111-116, 2024.
Article
em En
| MEDLINE
| ID: mdl-38223770
ABSTRACT
Purpose:
To report 3 cases of retinopathy secondary to ritonavir use in the treatment of HIV.Methods:
A retrospective review of patient records was performed for data including ophthalmic examination findings, demographic and HIV clinical characteristics, and progression of maculopathy disease. The review identified 3 patients with a history of HIV treated with antiretroviral therapy including ritonavir who had been evaluated for bilateral vision loss in both eyes.Results:
A fundus examination of each patient revealed characteristic macular atrophy, and optical coherence tomography demonstrated corresponding central outer retinal atrophy. Uveitis workup results were unremarkable. Given the characteristics of macular atrophy, history of ritonavir use, and the absence of intraocular inflammation, all 3 patients were diagnosed with bilateral ritonavir-associated retinopathy. Each patients' vision continued to deteriorate, even after the cessation of ritonavir.Conclusions:
Ritonavir toxicity should be considered in the differential diagnosis of retinopathy among patients with an exposure history.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Vitreoretin Dis
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos