Cardiovascular changes under the microgravity environment and the gut microbiome.
Life Sci Space Res (Amst)
; 40: 89-96, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38245353
ABSTRACT
In view of the critical role the gut microbiome plays in human health, it has become clear that astronauts' gut microbiota composition changes after spending time in space. Astronauts are exposed to several risks in space, including a protracted period of microgravity, radiation, and mechanical unloading of the body. Several deleterious effects of such an environment are reported, including orthostatic intolerance, cardiovascular endothelial dysfunction, cellular and molecular changes, and changes in the composition of the gut microbiome. Herein, the correlation between the gut microbiome and cardiovascular disease in a microgravity environment is evaluated. Additionally, the relationship between orthostatic hypotension, cardiac shrinkage and arrhythmias during spaceflight, and cellular alterations during spaceflight is reviewed. Given its impact on human health in general, modifying the gut microbiota may significantly promote astronaut health and performance. This is merited, given the prospect of augmented human activities in future space missions.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
3_ND
Problema de saúde:
3_zoonosis
Assunto principal:
Voo Espacial
/
Ausência de Peso
/
Microbioma Gastrointestinal
Limite:
Humans
Idioma:
En
Revista:
Life Sci Space Res (Amst)
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Emirados Árabes Unidos