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Immunoglobulin G4-related Dacryoadenitis Successfully Treated with Baricitinib.
Suenaga, Atsuhiko; Sawa, Naoki; Oba, Yuki; Ikuma, Daisuke; Sekine, Akinari; Yamanouchi, Masayuki; Hasegawa, Eiko; Mizuno, Hiroki; Suwabe, Tatsuya; Tsuji, Hideki; Kono, Kei; Kinowaki, Keiichi; Miyazono, Motoaki; Yamaguchi, Yutaka; Ubara, Yoshifumi.
Afiliação
  • Suenaga A; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Sawa N; Department of Nephrology, Saga University Internal Medicine, Japan.
  • Oba Y; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Ikuma D; Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
  • Sekine A; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Yamanouchi M; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Hasegawa E; Department of Nephrology and Rheumatology, Toranomon Hospital, Japan.
  • Mizuno H; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Suwabe T; Department of Nephrology, Saga University Internal Medicine, Japan.
  • Tsuji H; Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
  • Kono K; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Kinowaki K; Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.
  • Miyazono M; Department of Ophthalmology, the Cancer Institute Hospital of JFCR, Japan.
  • Yamaguchi Y; Department of Pathology, Toranomon Hospital, Japan.
  • Ubara Y; Department of Pathology, Toranomon Hospital, Japan.
Intern Med ; 63(3): 461-464, 2024.
Article em En | MEDLINE | ID: mdl-38296523
ABSTRACT
A 48-year-old woman visited our hospital because of bilateral lacrimal gland enlargement. Her serum immunoglobulin G4 (IgG4) level was high, and positron emission tomography-computed tomography showed significant positive findings in the bilateral lacrimal gland. A biopsy revealed a considerable increase in IgG4/CD138, leading to a diagnosis of IgG4-related dacryoadenitis. The disease did not respond to steroid therapy, so treatment was started with baricitinib because of exacerbation of the original atopic dermatitis and dacryoadenitis after the second dose of the coronavirus disease 2019 (COVID-19) vaccine. Baricitinib was effective for resolving both dermatitis and dacryoadenitis, and steroids were able to be discontinued. The IgG4 level also improved.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Pirazóis / Sulfonamidas / Azetidinas / Dacriocistite / Aparelho Lacrimal Tipo de estudo: Etiology_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Purinas / Pirazóis / Sulfonamidas / Azetidinas / Dacriocistite / Aparelho Lacrimal Tipo de estudo: Etiology_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão