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ICTV Virus Taxonomy Profile: Filoviridae 2024.
Biedenkopf, Nadine; Bukreyev, Alexander; Chandran, Kartik; Di Paola, Nicholas; Formenty, Pierre B H; Griffiths, Anthony; Hume, Adam J; Mühlberger, Elke; Netesov, Sergey V; Palacios, Gustavo; Paweska, Janusz T; Smither, Sophie; Takada, Ayato; Wahl, Victoria; Kuhn, Jens H.
Afiliação
  • Biedenkopf N; Philipps-University Marburg, Marburg, Germany.
  • Bukreyev A; The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
  • Chandran K; Albert Einstein College of Medicine, New York, USA.
  • Di Paola N; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA.
  • Formenty PBH; World Health Organization, Geneva, Switzerland.
  • Griffiths A; Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, USA.
  • Hume AJ; Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, USA.
  • Mühlberger E; Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, USA.
  • Netesov SV; Novosibirsk State University, Novosibirsk, Russia.
  • Palacios G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Paweska JT; National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham-Johannesburg, Gauteng, South Africa.
  • Smither S; Dstl, Porton Down, Wiltshire, UK.
  • Takada A; International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
  • Wahl V; National Biodefense Analysis and Countermeasures Center, Fort Detrick, Frederick, MD, USA.
  • Kuhn JH; Integrated Research Facility at Fort Detrick, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA.
J Gen Virol ; 105(2)2024 02.
Article em En | MEDLINE | ID: mdl-38305775
ABSTRACT
Filoviridae is a family of negative-sense RNA viruses with genomes of about 13.1-20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP1,2), a transcriptional activator (VP30) and a large protein (L) containing an RNA-directed RNA polymerase (RdRP) domain. All filovirid genomes encode additional proteins that vary among genera. Several filovirids (e.g., Ebola virus, Marburg virus) are pathogenic for humans and highly virulent. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Filoviridae, which is available at www.ictv.global/report/filoviridae.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rhabdoviridae / Ebolavirus / Marburgvirus Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rhabdoviridae / Ebolavirus / Marburgvirus Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha
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