Bacterial profiles detected in ventilator-associated pneumonia in Japan: A systematic review.
Respir Investig
; 62(3): 365-368, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38428090
ABSTRACT
The primary objective of this study was to identify the predominant organisms associated with ventilator-associated pneumonia (VAP) in Japan. Studies on VAP conducted in Japan were systematically reviewed, and seven studies with a total of 374 cases were included. The detection rate of each bacterium and multidrug-resistant (MDR) pathogen was analyzed using the inverse variance method. Pseudomonas aeruginosa was identified as the predominant pathogen in 29.2â¯% of cases, followed by methicillin-resistant Staphylococcus aureus (MRSA) (12.0â¯%), and Klebsiella spp. (9.5â¯%). An integrated analysis revealed a detection rate of 57.8â¯% (95â¯% confidence interval 48.7%-66.8â¯%) for MDR pathogens. This review highlights P. aeruginosa and MRSA as the predominant VAP-associated organisms in Japan, with a significant prevalence of MDR pathogens. This analysis provides valuable insights based on the regional distribution of bacteria detected in VAP, which is critical for selecting appropriate empirical therapy.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pseudomonas aeruginosa
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Farmacorresistência Bacteriana Múltipla
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Pneumonia Associada à Ventilação Mecânica
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Staphylococcus aureus Resistente à Meticilina
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Respir Investig
Ano de publicação:
2024
Tipo de documento:
Article