Therapeutic effects and molecular mechanisms of quercetin in gynecological disorders.
Biomed Pharmacother
; 173: 116418, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38461683
ABSTRACT
Quercetin is a representative flavonoid that is widely present in fruits, herbs, and vegetables. It is also an important active core component in traditional Chinese medicines. As an important flavonoid, quercetin has various properties and exerts antioxidant, anti-inflammatory, and cardioprotective effects. The public interest in quercetin is increasing, and quercetin has been used to prevent or treat numerous of diseases, such as polycystic ovary syndrome (PCOS), cancer, autoimmune diseases and chronic cardiovascular diseases, in clinical experiments and animal studies due to its powerful antioxidant properties and minimal side effects. Quercetin exerts marked pharmacological effects on gynecological disorders; however, there have been no reviews about the potential health benefits of quercetin in the context of gynecological disorders, including PCOS, premature ovary failure (POF), endometriosis (EM), ovarian cancer (OC), cervical cancer (CC) and endometrial carcinoma (EC). Thus, this review aimed to summarize the biological effects of quercetin on gynecological disorders and its mechanisms.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Ovário Policístico
/
Quercetina
Limite:
Animals
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Female
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Humans
Idioma:
En
Revista:
Biomed Pharmacother
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Biomed. pharmacother
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Biomedicine & pharmacotherapy
Ano de publicação:
2024
Tipo de documento:
Article