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Resolution of Wing-Beating Tremor and Magnetic Resonance Imaging Lesions in Wilson's Disease Following Penicillamine.
Brum, Igor Vilela; Parmera, Jacy Bezerra; Otani, Rafael Tomio Vicentini; Prates, Izaely Ramos; Lucato, Leandro Tavares; Cury, Rubens Gisbert; Barbosa, Egberto Reis.
Afiliação
  • Brum IV; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Parmera JB; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Otani RTV; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Prates IR; Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Lucato LT; Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Cury RG; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
  • Barbosa ER; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Article em En | MEDLINE | ID: mdl-38464913
ABSTRACT

Background:

The wing-beating tremor, characteristic of Wilson's disease (WD), is a disabling symptom that can be resistant to anti-copper and anti-tremor medications. Phenomenology Shown This video illustrates severe bilateral wing-beating tremor, moderate head and lower limb tremors, mild cervical dystonia, and subtle cerebellar ataxia, with nearly resolution after penicillamine treatment. Educational Value This case highlights a typical aspect of WD, emphasizing the importance of early detection and treatment, and its correlation with MRI findings. Highlights This case highlights the typical wing-beating tremor in Wilson's disease and its correlation with the involvement of the dentato-rubro-thalamic pathway. The early diagnosis and initiation of treatment with penicillamine resulted in an excellent clinical and radiological response.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Penicilamina / Degeneração Hepatolenticular Limite: Humans Idioma: En Revista: Tremor Other Hyperkinet Mov (N Y) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Penicilamina / Degeneração Hepatolenticular Limite: Humans Idioma: En Revista: Tremor Other Hyperkinet Mov (N Y) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil
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