Anisocytosis as a possible predictor of low cardiac output syndrome in children undergoing mitral valve surgery.
Adv Med Sci
; 69(1): 147-152, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38493878
ABSTRACT
PURPOSE:
Mitral valve surgery in children involves correcting congenital and acquired pathologies, with a reported mortality rate of 0.9%. Low cardiac output syndrome (LCOS) is a serious complication with the incidence of 20-25%. The aim of the study was to estimate possible prognostic factors of LCOS in children undergoing mitral valve procedure. MATERIAL ANDMETHOD:
This single-center retrospective analysis enrolled children aged <18 years who underwent mitral valve surgery during 24 year period. Preoperative clinical and laboratory parameters, and operative factors were analyzed.RESULTS:
Thirty consecutive pediatric patients (11 (37%) males and 19 (63%) females) in median (Q1 - Q3) age of 57 (25-115) months, who underwent mitral valve replacement, were included. The 30-day mortality was 7% (2 patients) and was related to postoperative multiorgan failure. LCOS occurred in 8 (27%) children. The receiver operator curve (ROC) analysis established parameters that have predictive value for LCOS occurrence cardiopulmonary bypass (CPB) time, with 89 âmin as optimal cut-off point (AUC â= â0.744, p â= â0.011) yielding sensitivity of 100% and specificity of 42.9%; left ventricular ejection fraction (LVEF) â< â60 % (AUC â= â0.824, okp â= â0.001) with sensitivity of 62.5% and specificity of 93.75%; and red blood cell distribution width (RDW) above 14.5 % (AUC â= â0.840, p â< â0.001; sensitivity of 87.5% and specificity of 75%).CONCLUSIONS:
In mitral valve replacement in pediatric patients, CPBtime above 89 âmin, preoperative LVEF below 60% and preoperative RDW above 14.5% can be regarded as the potential predictors of LCOS.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Baixo Débito Cardíaco
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Valva Mitral
Limite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
Adv Med Sci
Assunto da revista:
MEDICINA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Polônia