Monoclonal proliferation of B-cells with two integration sites of bovine leukemia virus proviral DNA in cattle with enzootic bovine leukosis.
J Vet Med Sci
; 86(6): 653-655, 2024 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-38631888
ABSTRACT
The present study analyzed B-cell clonality and bovine leukemia virus (BLV) provirus integration sites in cattle with enzootic bovine leukosis (EBL) having BLV proviral copy numbers less or greater than the number of bovine nucleated cells. EBL cattle with BLV copy numbers less than the number of bovine nucleated cells showed monoclonal and biclonal proliferation of B-cells with one BLV provirus integration site. On the other hand, EBL cattle with BLV copy numbers greater than the number of bovine nucleated cells showed monoclonal proliferation of B-cells with two BLV provirus integration sites. These results suggest that superinfection of BLV can occur in EBL cattle.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA Viral
/
Linfócitos B
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Provírus
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Leucose Enzoótica Bovina
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Vírus da Leucemia Bovina
Limite:
Animals
Idioma:
En
Revista:
J Vet Med Sci
/
J. vet. med. sci. (Online)
/
Journal of veterinary medical science (Online)
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão