PEG-functionalized aliphatic polycarbonate brushes with self-polishing dynamic antifouling properties.
Colloids Surf B Biointerfaces
; 239: 113936, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38703556
ABSTRACT
Hydrophilic antifouling polymers provide excellent antifouling effects under usual short-term use conditions, but the long-term accumulation of contaminants causes them to lose their antifouling properties. To overcome this drawback, surface-initiated ring-opening graft polymerization (SI-ROP) was performed on the surface of the material by applying the cyclic carbide monomer 4'-(fluorosulfonyl)benzyl-5-methyl-2-oxo-1,3-dioxane-5-carboxylate (FMC), which contains a sulfonylfluoride group on the side chain, followed by a "sulfur(IV)-fluorine exchange" (SuFEx) post click modification reaction to link the hydrophilic polyethylene glycol (PEG) to the polyFMC (PFMC) brush, and a novel antifouling strategy for self-polishing dynamic antifouling surfaces was developed. The experimental results showed that the antifouling surface could effectively prevent the adsorption of proteins such as bovine serum albumin (BSA, â¼96.4%), fibrinogen (Fg, â¼87.8%) and lysozyme (Lyz â¼69.4%) as well as the adhesion of microorganisms such as the bacteria Staphylococcus aureus (S. aureus) (â¼87.5%) and HeLa cells (â¼67.2%). Moreover, the enzymatically self-polished surface still has excellent antifouling properties. Therefore, this modification method has potential applications in the field of biosensors and novel antifouling materials.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cimento de Policarboxilato
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Polietilenoglicóis
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Staphylococcus aureus
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Propriedades de Superfície
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Aderência Bacteriana
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Soroalbumina Bovina
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Incrustação Biológica
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Colloids Surf B Biointerfaces
Assunto da revista:
QUIMICA
Ano de publicação:
2024
Tipo de documento:
Article