Naked mole-rats: at the heart of it.

Gabillard-Lefort, Claudie; Mialet-Perez, Jeanne; Lenaers, Guy; Baris, Olivier R

Naked mole-rats: at the heart of it.

Gabillard-Lefort, Claudie; Mialet-Perez, Jeanne; Lenaers, Guy; Baris, Olivier R.

Afiliação

Gabillard-Lefort C; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France.
Mialet-Perez J; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France.
Lenaers G; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France.
Baris OR; University of Angers, MitoLab, Unité MITOVASC, UMR CNRS 6015, INSERM U1083, SFR ICAT, Angers, France. Electronic address: olivier.baris@univ-angers.fr.

Trends Mol Med ; 30(10): 906-907, 2024 Oct.

Article em En | MEDLINE | ID: mdl-38816303

ABSTRACT

ABSTRACT

Faulkes et al. recently showed that naked mole-rats (NMRs) have a very distinctive cardiac gene expression profile among other African mole-rats, as well as metabolic variations that result from their chronic exposure to a hypoxic environment. These adaptations might underlie their resistance to cardiac ischemic injuries.

Assuntos

Ratos-Toupeira; Ratos-Toupeira/genética; Animais; Hipóxia/metabolismo; Hipóxia/genética; Miocárdio/metabolismo; Miocárdio/patologia; Humanos; Adaptação Fisiológica

Palavras-chave

cardioprotective adaptations; hypoxia; ischemia-reperfusion injuries; naked mole-rats

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ratos-Toupeira Limite: Animals / Humans Idioma: En Revista: Trends Mol Med / Trends in molecular medicine / Trends mol. med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2024 Tipo de documento: Article País de afiliação: França

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