Profilin affects microtubule dynamics via actin.

Ulrichs, Heidi; Shekhar, Shashank

Ulrichs, Heidi; Shekhar, Shashank.

Afiliação

Ulrichs H; Departments of Physics, Cell Biology and Biochemistry, Emory University, Atlanta, GA, USA.
Shekhar S; Departments of Physics, Cell Biology and Biochemistry, Emory University, Atlanta, GA, USA.

J Cell Biol ; 223(7)2024 07 01.

Article em En | MEDLINE | ID: mdl-38832903

ABSTRACT

ABSTRACT

Profilin binds microtubules in vitro. However, a new study by Vitriol and colleagues (https//doi.org/10.1083/jcb.202309097) now suggests that effects of profilin on microtubule dynamics in cells are indirect and result from its impact on actin dynamics rather than its direct binding to microtubules.

Assuntos

Actinas; Microtúbulos; Profilinas; Actinas/metabolismo; Microtúbulos/metabolismo; Profilinas/metabolismo; Profilinas/genética; Ligação Proteica

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Actinas / Profilinas / Microtúbulos Idioma: En Revista: J Cell Biol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

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