A case of autoimmune pulmonary alveolar proteinosis responding to oral statin therapy.
Respir Med Case Rep
; 50: 102042, 2024.
Article
em En
| MEDLINE
| ID: mdl-38845787
ABSTRACT
There is no approved drug treatment for autoimmune pulmonary alveolar proteinosis (APAP), although traditionally requires complex treatments such as whole lung lavage (WLL). We herein report on a 67-year-old man diagnosed with APAP. Treatment with atorvastatin (5 mg daily) resulted in significant improvement in symptoms, lung function, and computed tomography findings, with enhanced oxygenation, although serum anti-GM-CSF antibody levels remained elevated. This case suggests that the remission observed in this case could potentially be attributed to a direct effect of atorvastatin within the pulmonary alveoli. Statins may be considered as one of the treatment options for APAP.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Respir Med Case Rep
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão