Phenotyping OSA: Conceptualization and Implications for Treatment with Mandibular Advancement Devices.
Dent Clin North Am
; 68(3): 485-493, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38879282
ABSTRACT
Obstructive Sleep Apnea (OSA) is a common medical disorder and the most impacting sleep disturbance. OSA derive from the narrowing of the upper airway during sleep, which result in recurrent episodes of ventilatory disturbances expressed by an increased airflow resistance (flow limitation and hypopneas) and often an absence of ventilation (apneas). The high heterogeneity in the clinical picture of OSA turns diagnostic and treatment challenging. In the last decade different phenotypes, referring to specific categories of patients that can be distinguished from others by features and related clinical meaningful attributes, were identified. Those phenotypes may predict clinically important outcomes as those deriving from MAD therapy.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenótipo
/
Avanço Mandibular
/
Apneia Obstrutiva do Sono
Limite:
Humans
Idioma:
En
Revista:
Dent Clin North Am
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Brasil