Effective application of a direct-acting oral anticoagulants reversal agent in acute type A aortic dissection repair: A case report.
Asian Cardiovasc Thorac Ann
; 32(4): 213-214, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38884576
ABSTRACT
There are insufficient reports on the use of andexanet alfa in cardiac surgery. A 67-year-old man was diagnosed with type A aortic dissection and performed emergent surgery. His medical history included atrial fibrillation treated with Edoxaban. We performed total arch replacement. Despite administration of enough protamine, fresh frozen plasma, and platelet administration, controlling bleeding was difficult. Thus, Andexanet Alfa was initiated after CPB withdrawal. Surgical bleeding was dramatically controlled after its administration. There were no findings suggestive of an embolic event. In conclusion, administration of Andexanet Alfa is safe after cardiopulmonary bypass withdrawal.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Implante de Prótese Vascular
/
Inibidores do Fator Xa
/
Dissecção Aórtica
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Asian Cardiovasc Thorac Ann
Assunto da revista:
ANGIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão