Clinical-Pathological Features of Thyroid Neoplasms in Young Patients Diagnosed in a Single Center.
Life (Basel)
; 14(6)2024 May 28.
Article
em En
| MEDLINE
| ID: mdl-38929679
ABSTRACT
Background and objectives:
The aim of this study was to evaluate the clinical-pathological profile in young patients with thyroid cancer. Materials andmethods:
We realized a retrospective study on patients with thyroid neoplasms who underwent surgery at the "Pius Brinzeu" County Clinical Emergency Hospital in Timisoara, Romania. A comparative analysis of some parameters between two groups, young patients (<45 years) versus patients ≥45 years, was performed.Results:
A total of 211 patients met the study inclusion criteria, mostly females (86.26%) with a female/male ratio of 6.811. In patients <45 years old (25.64%), papillary thyroid carcinoma was identified in 51.85% of cases; in 53.85% of cases, the tumor was >1 cm; 13.46% had extrathyroidal extension (p = 0.0430); 21.15% capsule invasion (p = 0.1756); 23.08% lympho-vascular invasion (p = 0.0048); and 13.46% of cases locoregional nodal invasion (p = 0.0092).Conclusions:
Thyroid cancer in young people was associated with chronic lymphocytic thyroiditis and tumor progression parameters, identifying more cases of extrathyroidal extension, locoregional nodal invasion, lympho-vascular invasion and perineural invasion in young patients compared to older ones. For a better understanding of this pathology and to improve diagnosis and therapeutic management, more studies are needed for these patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Life (Basel)
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Romênia