A review of TEC family kinases and their inhibitors in the treatment of alopecia areata.
Arch Dermatol Res
; 316(8): 496, 2024 Jul 30.
Article
em En
| MEDLINE
| ID: mdl-39080140
ABSTRACT
The TEC (tyrosine kinase expressed in hepatocellular carcinoma) family kinases, an important class of protein kinases, play key roles in cell signaling and immune regulation. In this review, the association between the pathogenesis of alopecia areata and the structure and regulatory mechanisms of TEC family kinases in normal physiological processes, is explored. Furthermore, the potential clinical applications of TEC kinases and their inhibitors are highlighted by summarizing current insights into their mechanisms of action, clinical applications, and recent advancements in TEC kinase inhibitor research.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Tirosina Quinases
/
Transdução de Sinais
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Inibidores de Proteínas Quinases
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Alopecia em Áreas
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Arch Dermatol Res
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China