Naturalistic movies and encoding analysis define areal borders in marmoset third-tier visual cortex.
Prog Neurobiol
; 240: 102657, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-39103115
ABSTRACT
Accurate definition of the borders of cortical visual areas is essential for the study of neuronal processes leading to perception. However, data used for definition of areal boundaries have suffered from issues related to resolution, uniform coverage, or suitability for objective analysis, leading to ambiguity. Here, we present a novel approach that combines widefield optical imaging, presentation of naturalistic movies, and encoding model analysis, to objectively define borders in the primate extrastriate cortex. We applied this method to test conflicting hypotheses about the third-tier visual cortex, where areal boundaries have remained controversial. We demonstrate pronounced tuning preferences in the third-tier areas, and an organizational structure in which the dorsomedial area (DM) contains representations of both the upper and lower contralateral quadrants, and is located immediate anterior to V2. High-density electrophysiological recordings with a Neuropixels probe confirm these findings. Our encoding-model approach offers a powerful, objective way to disambiguate areal boundaries.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Visual
/
Callithrix
Limite:
Animals
Idioma:
En
Revista:
Prog Neurobiol
/
Prog. neurobiol
/
Progress in neurobiology
Ano de publicação:
2024
Tipo de documento:
Article