Based on Cardiopulmonary Exercise Testing to Construct and Validate Nomogram of Long-Term Prognosis Within 12 Months for NSCLC.
Clin Respir J
; 18(8): e13806, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-39118279
ABSTRACT
OBJECTIVE:
Construction nomogram was to effectively predict long-term prognosis in patients with non-small cell lung cancer (NSCLC). MATERIALS ANDMETHODS:
The nomogram is developed by a retrospective study of 347 patients with NSCLC who underwent cardiopulmonary exercise testing (CPET) before surgery from May 2019 to February 2022. Cross-validation divided the data into a training cohort and validation cohort. The discrimination and accuracy ability of the nomogram were proofed by concordance index (C-index), calibration curve, receiver operating characteristic (ROC) curve, the area under the curve (AUC), and time-dependent ROC in validation cohort.RESULTS:
Age, intraoperative blood loss, VO2 peak, and VE/VCO2 slope were included in the model of nomogram. The model demonstrated good discrimination and accuracy with C-index of 0.770 (95% CI 0.712-0.822). AUC of 6 (AUC 0.789, 95% CI 0.726-0.851) and 12 months (AUC 0.787, 95% CI 0.724-0.850) were shown in ROC. Time-independent ROC maintains a good effect within 12 months.CONCLUSION:
We developed a nomogram based on CPET. This model has a good ability of discrimination and accuracy. It could help clinicians to make treatment decision in clinical decision.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Pulmonar de Células não Pequenas
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Nomogramas
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Teste de Esforço
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Neoplasias Pulmonares
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Respir J
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China