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A novel tumor theranostic strategy based on metabolic glycoengineering and disulfidptosis.
Li, Jie; Chang, Hao; Zhang, Pengzhe; Hou, Liyu; Li, Wei; Zhang, Yixin; Lao, Zhiqi.
Afiliação
  • Li J; Department of Plastic and Reconstructive Surgery, Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200011, China. wei.li@siat.ac.cn.
  • Chang H; Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University: The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, China.
  • Zhang P; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. zq.lao@siat.ac.cn.
  • Hou L; Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University: The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, China.
  • Li W; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. zq.lao@siat.ac.cn.
  • Zhang Y; Department of Plastic and Reconstructive Surgery, Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200011, China. wei.li@siat.ac.cn.
  • Lao Z; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. zq.lao@siat.ac.cn.
Org Biomol Chem ; 22(34): 6946-6949, 2024 08 28.
Article em En | MEDLINE | ID: mdl-39129513
ABSTRACT
Traditional metabolic glycoengineering involves participation of a monofunctional unnatural monosaccharide. To broaden the application boundary of this powerful technique, a bifunctional molecule, Ac4ManNSSN3, is designed and applied for a tumor theranostic strategy in this work. The results from both cell and animal experiments show good in situ tumor detection and tumor inhibition effects.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanomedicina Teranóstica Limite: Animals / Humans Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanomedicina Teranóstica Limite: Animals / Humans Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China