Scarless genome editing technology and its application to crop improvement.
Breed Sci
; 74(1): 32-36, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-39246436
ABSTRACT
The advent of CRISPR/Cas9 has had a disruptive impact on the world by bringing about dramatic progress and rapid penetration of genome editing technology. However, even though gene disruption can be easily achieved, there has been a challenge in freely changing the sequence. To solve this problem, various novel technologies have emerged in recent years to realize free rewriting of genome sequences. In this review, scarless editing by two-step HDR, a technology that can freely rewrite genomes from a single nucleotide to more than several thousand nucleotides, will be introduced.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Breed Sci
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos