In vivo metabolism of aminopyrine by the larvae of the helminth Heligmosomoides polygyrus.
Parasitol Res
; 81(4): 302-4, 1995.
Article
em En
| MEDLINE
| ID: mdl-7624287
ABSTRACT
The in vivo N-dealkylation of [13C-2]-labeled aminopyrine by the L1-L2 larvae of Heligmosomoides polygyrus was demonstrated by the use of a sensitive gas chromatography-mass spectrometry method. This is the first evidence for the possible existence of a cytochrome P-450-dependent activity in helminths.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nematospiroides dubius
/
Aminopirina
Limite:
Animals
Idioma:
En
Revista:
Parasitol Res
Assunto da revista:
PARASITOLOGIA
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
França