Elevation of CSF somatostatin concentrations in mania.
Am J Psychiatry
; 152(12): 1807-9, 1995 Dec.
Article
em En
| MEDLINE
| ID: mdl-8526251
ABSTRACT
OBJECTIVE:
The aim of this study was to compare levels of CSF somatostatin (somatotropin release-inhibiting factor) in drug-free patients with different major psychiatric disorders.METHOD:
CSF somatostatin concentrations were measured in 66 drug-free inpatients with Research Diagnostic Criteria diagnoses of schizophrenia, major depressive disorder, manic disorder, or schizoaffective disorder.RESULTS:
In comparison with both the patients with schizophrenia and the patients with schizoaffective disorder, the manic patients had markedly elevated CSF somatostatin concentrations. The depressed patients had significantly higher levels than the schizophrenic patients.CONCLUSIONS:
Mania is associated with relatively higher CSF somatostatin concentrations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Bipolar
/
Somatostatina
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Psychiatry
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Estados Unidos