Evaluation of a monoclonal antibody-based sandwich-ELISA for detection of circulating Schistosoma japonicum antigen (Sj31/32) in an endemic area of China.
Trop Med Int Health
; 1(6): 847-50, 1996 Dec.
Article
em En
| MEDLINE
| ID: mdl-8980599
ABSTRACT
A sandwich-ELISA specific for 31/32 kDa schistosome proteins was used to trace infections in a Chinese population living in a low endemicity area for schistosomiasis japonica. The study population included 304 persons for whom records were available from 1992 onwards. In 1994, 2 individuals were positive in the miracidial hatching assay performed with 30 g of stools. The ELISA gave positive results for 8 individuals, including these 2 with active infections. Of the remaining 6 ELISA-positive, 5 had excreted eggs and received praziquantel in 1993 and may have harboured residual worms in 1994. It is concluded that this ELISA is able, in a low prevalence situation, to identify the few infected individuals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
3_ND
Problema de saúde:
3_helminthiasis
/
3_neglected_diseases
/
3_schistosomiasis
/
3_zoonosis
Assunto principal:
Schistosoma japonicum
/
Esquistossomose Japônica
/
Anticorpos Monoclonais
/
Antígenos de Helmintos
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Trop Med Int Health
Assunto da revista:
MEDICINA TROPICAL
/
SAUDE PUBLICA
Ano de publicação:
1996
Tipo de documento:
Article