Human fecal PCDD/F-excretion exceeds the dietary intake.
Chemosphere
; 37(9-12): 1825-31, 1998.
Article
em En
| MEDLINE
| ID: mdl-9828311
ABSTRACT
A mass balance of human dietary PCDD/F-intake and fecal PCDD/F-excretion was carried out. The participants of the study were seven male and seven female adults between the ages of 24 to 64 years, living in North Rhine-Westphalia, Germany. The PCDD/F-intake was measured using the duplicate method. Sampling time of each food duplicate covered three days. The fecal PCDD/F-excretion was measured by collecting the feces which corresponded to the food duplicates. The mean daily dietary PCDD/F-intake was 49 pg I-TEq/d (range 23-96 pg I-TEq/d) and therewith lower than that estimated in the past. The mean daily fecal PCDD/F-excretion was 98 pg I-TEq/d (40-200 pg I-TEq/d). This is twice the amount of the PCDD/F-intake. The fecal excretion of OCDD was especially higher than the dietary intake (mean 7 fold, range 1.2-21 fold). The differences between PCDD/F-intake and PCDD/F-excretion may be caused by a reduction of the body burden as a consequence of decreasing PCDD/F-intake. Other explanations were additional sources of exposure to PCDD/F or de novo formation of PCDD/F in the human body.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
Problema de saúde:
2_quimicos_contaminacion
Assunto principal:
Benzofuranos
/
Dieta
/
Dibenzodioxinas Policloradas
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Chemosphere
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Alemanha