ABSTRACT
Antecedentes y Objetivos: La metastasectomía pulmonar es un procedimiento aceptado para tratamiento de lsa metástasis (Mts) pulmonares del carcinoma colorrectal. Los pacientes no tratados presentan supervivencia a 5 años por debajo del 5%. No existe actualmente quimioterapia efectiva. Se relata en la bibliografía internacional una supervivencia actuarial de 20-40% con carciroma colorrectal con/sin resección previa de secundarismo hepático. Lugar de aplicación: Hospital privado universitario. Diseño: Modelo retrospectivo. Método: Se analizan 40 pacientes, estudiándose la supervivencia según diferentes criterios. La metastasectomía fue indicada en casos de: tumor primario controlado, ausencia de Mts extratorácicas y condición clínica favorable. Se incluyeron sólo los pacientes con resección completa de las Mts. Todos ellos fueron evaluados previamente para recidiva local o compromiso sistémico del cáncer primario. Resultados: La supervivencia actuarial a 5 años de toda la población desde la metastasectomía pulmonar fue 37,9%. Factores como: edad, sexo, tamaño y número de metástasis, intervalo libre de enfermedad, metastesectomía hepática previa y nivel preoperatorio de CEA no influyeron significatimente en los resultados. Conclusión: Una bien seleccionada población de pacientes con Mts pulmonares de carcinoma colorrectal de beneficia claramente con la resección quirúrgica de las mismas por toracotomía.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Colorectal Neoplasms/surgery , Colorectal Neoplasms/pathology , Lung Neoplasms/surgery , Lung Neoplasms/diagnosis , Lung Neoplasms/secondary , Neoplasm MetastasisABSTRACT
INTRODUCTION: Superior vena cava syndrome (SVCS) is associated to a malignant tumor in more than 90% of cases; being the lung cancer the most frequent (80%). SVCS has a benign cause in less than 5% of cases. Endovascular stenting has been proposed as the primary treatment of choice. We report our experience in SVC recanalization through the use of self-expanding vascular stents as treatment of life-threatening SVCS of benign and malignant etiology. MATERIALS AND METHODS: Between January 1994 and April 2002 44 patients with critical SVCS, were treated at the Hospital Italiano de Buenos Aires. Forty nine self-expanding endovascular metallic stents were percutaneously placed in the SVC. Thirty-one (70%) patients were male and 13 (30%) were female. The mean age was 55.6 years (range: 21-77). The etiology of SVCS was malignant in 40 cases and benign in 4. The malignant causes included lung cancer: 37 (37/44 - 92.5%), lymphoma: 1 (2.5%), chondrosarcoma 1 (2.5%), melanoma 1 (2.5%). The benign etiology corresponded to central catheters (N: 2) and post-radiation fibrosis (N: 2). Cavography showed complete occlusion of SVC in 12 cases (27%) and significant partial stenosis in 32 cases (73%). Thrombi associated with tumor stenosis were present in 25 (57%) patients. RESULTS: All procedures were technically successful. No stent migration was observed. Thirty-two patients with malignant tumor ultimately died due to the progression of the disease. Mean survival time was 193 days (range: 25-578). SVCS recurrence was observed on six occasions. In four patients a new stent was placed. Symptomatic improvement was dramatically seen within 24-48 h after stent placement in 40 patients (90.9%) and 83.3% out of the cases (38/44) were symptoms-free during the rest of the disease. Three patients died in the 7 following days. CONCLUSION: The use of self-expanding vascular endoprostheses in the recanalization treatment of SVC in SVCS due to a malignant or benign etiology offers excellent results with rapid and prolonged remission of symptoms.
Subject(s)
Blood Vessel Prosthesis Implantation , Stents , Superior Vena Cava Syndrome/surgery , Adult , Aged , Blood Vessel Prosthesis Implantation/mortality , Catheterization/adverse effects , Chondrosarcoma/complications , Chondrosarcoma/surgery , Female , Humans , Lung Neoplasms/complications , Lung Neoplasms/surgery , Lymphoma, Non-Hodgkin/complications , Lymphoma, Non-Hodgkin/surgery , Male , Melanoma/complications , Melanoma/surgery , Middle Aged , Recurrence , Reoperation , Superior Vena Cava Syndrome/etiology , Superior Vena Cava Syndrome/mortality , Survival Rate , Thrombosis/complications , Thrombosis/surgery , Treatment OutcomeABSTRACT
We report the laparoscopic transhiatal thoracic duct ligation to solve postoperative chylothorax after right total pleurectomy for malignant diffuse mesothelioma.
Subject(s)
Chylothorax/surgery , Postoperative Complications/surgery , Thoracic Duct/surgery , Female , Humans , Laparoscopy , Ligation , Mesothelioma/surgery , Middle Aged , Pleural Neoplasms/surgeryABSTRACT
This article will provide a brief background on Argentina and then summarize the country's medical and surgical history, undergraduate and postgraduate training programs, residency programs, surgical associations, research, and the Argentinean Journal of Surgery (Revista Argentina de Cirugía). Surgery in Argentina is at the same level as that of most developed countries although transplantation, traumatology, and laparoscopic surgery have been emphasized.
Subject(s)
Education, Medical/statistics & numerical data , General Surgery/history , Argentina , Education, Medical/history , General Surgery/education , History, 19th Century , History, 20th Century , Humans , Laparoscopy , Organ Transplantation/history , Organ Transplantation/trends , Research , Schools, Medical/history , Schools, Medical/statistics & numerical data , Societies, Medical/historyABSTRACT
Introducción: los timomas constituyen neoplasias infrecuentes, de presentación variada ya sea por manifestaciones locales o síndromes inmunológicos complejos. Material y métodos: se revisaron los registros de pacientes con timomas entre 1980/1997. Se analizaron datos clínicos, quirúrgicos, complicaciones, evolución y sobrevida. Resultados: cuarenta y tres pacientes con tumores tímicos ( Timomas 28). Edad X 52,3 años, 17 mujeres. Trece pacientes asintomáticos (46,4 por ciento), 15 restantes: Mistenia Gravis (MG) en 8 casos (28,5 por ciento), dolor 5, disnea 2, otros 1. Todos con radiografía de tórax anormal ( bordes netos fue el patrón predominante). Punción con aguja fina diagnosticó 7/8 casos: el resto del diagnóstico fue de sospecha. Todos intervenidos quirúrgicamente, frecuentemente por esternotomía vertical (57 por ciento). En 21 pacientes con resección simple (75 por ciento), el resto ampliada. La histología más frecuente: linfoepitelial 13 casos (46,4 por ciento). Peso y tamaño promedio de piezas: 9,9 cm y 298 gr (r 4,5 a 24 cm y 33 gr a 900 gr). Doce casos estadío I (EI) (42,9 por ciento), 9 E II (32,1 por ciento) y 7 E III y IV (25 por ciento). No se correlacionaron tamaño y peso con MG ni invasión. Tampoco entre E y MG. Todos requirieron intubación orotraqueal durante cirugía, y 11 asistidos respiratoriamente luego (ARM) (39,3 por ciento). Tiempo promedio de ARM de 6.3 días, mayor en pac. con MG (6,6 días vs 0,8 días) p<0,05. Dos fallecieron en post-operatorio inmediato en ARM con MG y tres posteriormente ( progresión tumoral, MG, y tromboembolismo pulmonar). Trece efectuaron radioterapia y 3 quimioterapia. Del total de pacientes fallecidos tres tenían MG, siendo el grupo con mayor mortalidad (37,5 por ciento vs 10 por ciento). La sobrevida global a 5 años fue 73 por ciento. Conclusiones: el timoma es una patología infrecuente. Su lento crecimiento explicaría el tamaño que alcanzan. No existió correlación entre grado de invasión con peso, tamaño, ni con presencia de MG. El tiempo de ARM y la mortalidad fue mayor en aquéllos con MG
Subject(s)
Humans , Male , Adolescent , Adult , Female , Middle Aged , Survival Analysis , Thymoma , Cisplatin , Doxorubicin , Etoposide , Myasthenia Gravis , Neoplasm Staging , ThymomaABSTRACT
UNLABELLED: In patients with hypoglycemic syndrome, preoperative localization of the insulinoma highly contributes to surgical removal. When the ultrasonography, computed tomography, magnetic resonance and pancreatic angiography fail to visualize the tumor, they are called occult insulinomas (OI). In this paper we describe the results of a new diagnostic method to localize OI, performed in 5 patients with hypoglycemic syndrome secondary to endogenous hyperinsulinism. In four out of five patients, computed tomography, magnetic resonance and angiography failed to show any tumor. In just one single case, these imaging methods showed the pancreatic tumor. All patients were studied by selective intraarterial pancreatic stimulation (SIPS): a) infusion of calcium gluconate (0.025 mEq/kg) in each artery that supplies the pancreas: gastroduodenal, superior mesenteric and splenic arteries as well as the hepatic artery; b) insulin venous sampling in the right supra-hepatic vein at 30 and 60 seconds after arterial stimulation (in one patient an additional sample at 90 seconds was obtained). The study was considered pathologic when the gradient (basal vs post-stimulus) increased at least 100%. RESULTS: In all five patients a pathological gradient was found. The suspected preoperative localization of the tumor was confirmed at surgery in four cases. The anatomopathologic examination revealed insulinoma in four cases and malignant insulinoma in the remaining. It is concluded that the results of this preliminary experience show the usefulness of SIPS in the preoperative localization of occult insulinomas.