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1.
Highlight report: Cell type selection for toxicity testing.
Bolt, H M.
EXCLI J ; 17: 1180-1181, 2018.
Article in English | MEDLINE | ID: mdl-30713478
2.
Highlight report: physiologically-based modeling of diseased liver tissue.
Bolt, H M.
Arch Toxicol ; 91(12): 4017-4018, 2017 12.
Article in English | MEDLINE | ID: mdl-29177810

Subject(s)
Liver , Models, Biological , Tissue Distribution
3.
Highlight report: Occupational urinary bladder cancer.
Bolt, H M.
EXCLI J ; 16: 1319-1320, 2017.
Article in English | MEDLINE | ID: mdl-29333133
4.
Highlight report: The pseudolobule in liver fibrosis.
Bolt, H M.
EXCLI J ; 16: 1321-1322, 2017.
Article in English | MEDLINE | ID: mdl-29333134
5.
Highlight report: critical evaluation of key evidence on health hazards of the general European population by exposure to arsenic.
Bolt, H M.
Arch Toxicol ; 89(12): 2455-7, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26603052

Subject(s)
Arsenic , Hazardous Substances , Environmental Exposure , Humans , Water Pollutants, Chemical
6.
Highlight report: cytoprotective signaling in toxicology.
Bolt, H M; Marchan, R.
Arch Toxicol ; 89(11): 2189-91, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26525396

Subject(s)
Cytoprotection/physiology , Signal Transduction/drug effects , Toxicology , Humans , Stress, Physiological/drug effects
7.
Highlight report: biomarkers of acetaminophen-induced liver injury.
Bolt, H M.
Arch Toxicol ; 89(11): 2193-4, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26531746

Subject(s)
Acetaminophen/adverse effects , Analgesics, Non-Narcotic/adverse effects , Chemical and Drug Induced Liver Injury/ethnology , Animals , Humans
8.
In vitro systems: current limitations and future perspectives.
Ghallab, Ahmed; Bolt, H M.
Arch Toxicol ; 88(12): 2085-7, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25370013

Subject(s)
In Vitro Techniques , Toxicology , Animals , Humans , In Vitro Techniques/methods , In Vitro Techniques/standards , In Vitro Techniques/trends , Toxicology/methods , Toxicology/trends
9.
Standard compounds for establishment of in vitro test systems.
Hengstler, J G; Marchan, R; Bolt, H M.
Arch Toxicol ; 88(12): 2083-4, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25354799

Subject(s)
Animal Testing Alternatives/standards , In Vitro Techniques/standards , Liver/drug effects , Toxicology/standards , Animals , Humans
10.
Research on plant extracts and phytochemicals: criteria for evaluation.
Hammad, S; Marchan, R; Bolt, H M.
Arch Toxicol ; 88(1): 11-3, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24185950

Subject(s)
Biomedical Research/methods , Phytochemicals/pharmacology , Plant Extracts/pharmacology , Biomedical Research/standards , Drug Discovery/methods
11.
The cytoprotective and the dark side of Nrf2.
Marchan, R; Bolt, H M.
Arch Toxicol ; 87(12): 2047-50, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24232176

Subject(s)
Carcinogens/metabolism , Cytoprotection , NF-E2-Related Factor 2/physiology , Carcinogens/antagonists & inhibitors , Humans , NF-E2-Related Factor 2/genetics , NF-E2-Related Factor 2/metabolism
12.
Recent developments in in vitro toxicology: perspectives of European research and Tox21.
Marchan, R; van Thriel, C; Bolt, H M.
Arch Toxicol ; 87(12): 2043-6, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24221536

Subject(s)
Animal Testing Alternatives/trends , Toxicity Tests/trends , Toxicology/trends , Animals , High-Throughput Screening Assays , Humans , In Vitro Techniques , United States , Xenobiotics/metabolism , Xenobiotics/toxicity
13.
Human bladder cancer risk calculation based on genome-wide analysis of genetic variants.
Bolt, H M.
Arch Toxicol ; 87(3): 397-9, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23404679

Subject(s)
Biomarkers, Tumor/genetics , Genetic Predisposition to Disease , Polymorphism, Single Nucleotide/genetics , Smoking/genetics , Urinary Bladder Neoplasms/etiology , Humans
14.
Recent developments in nanotoxicology.
Bolt, H M; Marchan, R; Hengstler, J G.
Arch Toxicol ; 87(6): 927-8, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22526375

Subject(s)
Nanostructures/adverse effects , Nanotechnology/trends , Toxicology/trends , Animals , Humans , Risk Assessment , Toxicity Tests
15.
Hepatocellular cancer.
Godoy, P; Bolt, H M.
Arch Toxicol ; 87(2): 225-6, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23263404

Subject(s)
Carcinoma, Hepatocellular/pathology , Carcinoma, Hepatocellular/physiopathology , Liver Neoplasms/pathology , Liver Neoplasms/physiopathology , Animals , Carcinoma, Hepatocellular/etiology , Disease Models, Animal , Humans , Liver/cytology , Liver Neoplasms/etiology , Tumor Microenvironment
16.
Developmental neurotoxicity testing with human embryonic stem cell-derived in vitro systems: the novel FP7 ESNATS tests are available.
Bolt, H M.
Arch Toxicol ; 87(1): 5-6, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23192237

Subject(s)
Embryonic Stem Cells/drug effects , Gene Expression Profiling , Mutagenicity Tests/methods , Neurotoxicity Syndromes/genetics , Humans
17.
Role of heat shock proteins in stress response and carcinogenesis.
Cadenas, C; Marchan, R; Bolt, H M.
Arch Toxicol ; 87(1): 1-2, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23184253

Subject(s)
DNA-Binding Proteins/genetics , Heat-Shock Proteins/physiology , Neoplasms/genetics , Neoplasms/pathology , Transcription Factors/genetics , Heat Shock Transcription Factors , Humans
18.
Relevance of genetic disposition versus environmental exposure for cancer risk: an old controversy revisited with novel methods.
Bolt, H M.
EXCLI J ; 12: 79-80, 2013.
Article in English | MEDLINE | ID: mdl-27034631
19.
Transcriptomics in developmental toxicity testing.
Bolt, H M.
EXCLI J ; 12: 1027-9, 2013.
Article in English | MEDLINE | ID: mdl-27034643
20.
Novel ROS-scavenging strategies.
Reif, R; Bolt, H M.
Arch Toxicol ; 86(11): 1647-8, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23052198

Subject(s)
Apoptosis , Neoplasms/pathology , Neoplasms/prevention & control , Oxidative Stress , Reactive Oxygen Species/metabolism , Humans
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