ABSTRACT
The results of a study on smoking habits of Florence inhabitants (14 years of age or more) are reported. A random sample of general population of the town (1744 males and 1977 females) was recruited throughout the registration office and interviewed by mail or telephone. General compliance was approximately 85%. Thirty-seven percent of males and 25% of females were current cigarette smokers, 29% of males and 11% of females were ex smokers. Males were heavier smokers both as concerns duration of the habit and daily amount of cigarettes. In males born after 1930 the smoking prevalence decreased gradually by period of birth, while it increased in females born before 1960. As a result the smoking habits of younger cohorts were similar in males and in females. In each sex age-adjusted smoking prevalence showed important differences by educational groups and in respect to national averages.
Subject(s)
Smoking/epidemiology , Adolescent , Adult , Age Distribution , Aged , Female , Humans , Italy/epidemiology , Male , Middle Aged , Sex DistributionABSTRACT
Biopsy is the technique of choice for the definitive diagnosis of endometrial carcinoma. Since lymphatic tumor spread has been demonstrated to depend on the degree of myometrial involvement, the definition of the latter with imaging techniques may significantly affect both prognosis and therapy. We investigated, by means of MR imaging at 0.5 T, 14 patients with endometrial carcinoma, to assess both tumor stage and myometrial involvement. FIGO staging system was employed, and M parameter evaluated (M0 = no myometrial involvement; M1 = involvement confined to the inner third; M2 = involvement confined to the middle third; M3 = involvement of the whole myometrium). Another parameter was the characteristic high signal of the tumor on PD and T2W images. The patients were then operated and MR information was correlated with surgical findings. Overall diagnostic accuracy of MR imaging was 85.7% in tumor staging, and 92.2% in defining M parameter. Tumor spread into adnexa and into cervical canal was poorly demonstrated by MR imaging.
Subject(s)
Magnetic Resonance Imaging , Uterine Neoplasms/diagnostic imaging , Aged , Female , Humans , Middle Aged , Neoplasm Staging , Radiography , Uterine Neoplasms/pathologyABSTRACT
In order to evaluate the reliability of thoraco-mediastinal CT in the preoperative evaluation of primary lung cancer, regarding "N" (lymph nodes) parameter, we compared CT data with those obtained at histopathology of mediastinal lymph nodes. We re-examined 130 patients who had undergone lobectomy or pneumonectomy combined with mediastinal node dissection. CT criterion of neoplastic nodal involvement is morphological, based on size of the node as related to its location. CT is very sensitive in evaluating both normal and pathological nodes but not likewise specific; in fact, it does not allow differential diagnosis between neoplastic and phlogistic causes. This limitation must be kept in mind in the preoperative evaluation of the "N" parameter. Moreover, CT findings of mediastinal involvement on the opposite side (N3) must be confirmed with mediastinoscopy or CT-guided biopsy before ruling radical surgery out.
Subject(s)
Lung Neoplasms/pathology , Tomography, X-Ray Computed , Adult , Aged , Bronchial Neoplasms/pathology , Female , Humans , Lymphatic Metastasis , Male , Middle Aged , Neoplasm Staging , Predictive Value of Tests , Preoperative CareSubject(s)
Environmental Exposure , Lung Neoplasms/mortality , Female , Humans , Lung Neoplasms/etiology , Male , Smoking/adverse effectsABSTRACT
CT-guided percutaneous fine-needle biopsy (FNB) is the method of choice in the histological characterization of mediastinum and lung lesions in which a diagnosis could not be reached through noninvasive methods such as cytology of the sputum, or biopsy during bronchoscopy. FNB represents an alternative to diagnostic thoracotomy: it is, in fact, less invasive, it can be carried out with no need for hospitalization, and has a low incidence of complications. FNB diagnostic accuracy is very high, as our results prove: accuracy 89.6%, sensitivity 87.6% and specificity 98%. Our series includes 419 percutaneous fine-needle biopsies.
Subject(s)
Biopsy, Needle/methods , Lung/pathology , Mediastinum/pathology , Biopsy, Needle/adverse effects , Biopsy, Needle/instrumentation , Cytodiagnosis/methods , Diagnosis, Differential , Evaluation Studies as Topic , Humans , Lung/diagnostic imaging , Lung Diseases/diagnosis , Lung Diseases/pathology , Mediastinal Diseases/diagnosis , Mediastinal Diseases/pathology , Mediastinum/diagnostic imaging , Needles , Tomography, X-Ray ComputedABSTRACT
Magnetic resonance (MR) imaging and high resolution computed tomography (CT) have been compared in 37 patients who had expansive processes of the lung and the mediastinum. MR imaging and CT scanning gave identical results in 32 patients; in 5 patients, CT scanning has proved more useful in evaluating the stag e of primary lung tumors. MR imaging often gives more information about the actual size of the tumor, and the involvement of close structures, although it does not modify staging of the tumor. MR imaging has the advantage to differentiate hilar adenopathy from blood vessel structures. Evaluation of T2 relaxing time (that we have performed in the same location of thin-needle biopsy aspiration), however, did not prove to be of diagnostic significance; this indicates that MR imaging at the moment is not suitable for tissue typification.