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Res Commun Chem Pathol Pharmacol ; 18(2): 369-72, 1977 Oct.
Article in English | MEDLINE | ID: mdl-918353

ABSTRACT

Male and female Long-Evans rats placed on a diet of Purina laboratory chow supplemented with 2.5 and 5.0% oxalic acid for a period of 70 days revealed decreased body weights and restricted growth rates. Ingestion of 5.0% oxalic acid depressed absolute organ weights of several visceral and endocrine tissues but enhanced the organ/body weight ratios of both male and female rats. Vaginal smears indicated disrupted estrous cycles.


Subject(s)
Growth/drug effects , Oxalates/pharmacology , Reproduction/drug effects , Animals , Body Weight/drug effects , Diet , Female , Male , Organ Size/drug effects , Oxalates/administration & dosage , Rats , Time Factors
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