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1.
BMJ Open ; 6(10): e011934, 2016 10 25.
Article in English | MEDLINE | ID: mdl-27798000

ABSTRACT

OBJECTIVES: To explore views of all stakeholders (patients, optometrists, general practitioners (GPs), commissioners and ophthalmologists) regarding the operation of community-based enhanced optometric services. DESIGN: Qualitative study using mixed methods (patient satisfaction surveys, semi-structured telephone interviews and optometrist focus groups). SETTING: A minor eye conditions scheme (MECS) and glaucoma referral refinement scheme (GRRS) provided by accredited community optometrists. PARTICIPANTS: 189 patients, 25 community optometrists, 4 glaucoma specialist hospital optometrists (GRRS), 5 ophthalmologists, 6 GPs (MECS), 4 commissioners. RESULTS: Overall, 99% (GRRS) and 100% (MECS) patients were satisfied with their optometrists' examination. The vast majority rated the following as 'very good'; examination duration, optometrists' listening skills, explanations of tests and management, patient involvement in decision-making, treating the patient with care and concern. 99% of MECS patients would recommend the service. Manchester optometrists were enthusiastic about GRRS, feeling fortunate to practise in a 'pro-optometry' area. No major negatives were reported, although both schemes were limited to patients resident within certain postcode areas, and some inappropriate GP referrals occurred (MECS). Communication with hospitals was praised in GRRS but was variable, depending on hospital (MECS). Training for both schemes was valuable and appropriate but should be ongoing. MECS GPs were very supportive, reporting the scheme would reduce secondary care referral numbers, although some MECS patients were referred back to GPs for medication. Ophthalmologists (MECS and GRRS) expressed very positive views and widely acknowledged that these new care pathways would reduce unnecessary referrals and shorten patient waiting times. Commissioners felt both schemes met or exceeded expectations in terms of quality of care, allowing patients to be seen quicker and more efficiently. CONCLUSIONS: Locally commissioned schemes can be a positive experience for all involved. With appropriate training, clear referral pathways and good communication, community optometrists can offer high-quality services that are highly acceptable to patients, health professionals and commissioners.


Subject(s)
Attitude of Health Personnel , Community Health Services , Delivery of Health Care/methods , Eye Diseases , Optometry , Patient Satisfaction , Professional Role , England , Eye Diseases/diagnosis , General Practitioners , Glaucoma , Humans , Ophthalmologists , Optometrists , Referral and Consultation
2.
BMJ Open ; 6(8): e011832, 2016 08 10.
Article in English | MEDLINE | ID: mdl-27515757

ABSTRACT

BACKGROUND: The establishment of minor eye conditions schemes (MECS) within community optometric practices provides a mechanism for the timely assessment of patients presenting with a range of acute eye conditions. This has the potential to reduce waiting times and avoid unnecessary referrals to hospital eye services (HES). OBJECTIVE: To evaluate the clinical effectiveness, impact on hospital attendances and patient satisfaction with a minor eye service provided by community optometrists. METHODS: Activity and outcome data were collected for 12 months in the Lambeth and Lewisham MECS. A patient satisfaction questionnaire was given to patients at the end of their MECS appointment. A retrospective difference-in-differences analysis of hospital activity compared changes in the volume of referrals by general practitioners (GPs) from a period before (April 2011-March 2013) to after (April 2013-March 2015) the introduction of the scheme in Lambeth and Lewisham relative to a neighbouring area (Southwark) where the scheme had not been commissioned. Appropriateness of case management was assessed by consensus using clinical members of the research team. RESULTS: A total of 2123 patients accessed the scheme. Approximately two-thirds of patients (67.5%) were referred by their GP. The commonest reasons for patients attending for a MECS assessment were 'red eye' (36.7% of patients), 'painful white eye' (11.1%) and 'flashes and floaters' (10.2%). A total of 64.1% of patients were managed in optometric practice and 18.9% were referred to the HES; of these, 89.2% had been appropriately referred. First attendances to HES referred by GPs reduced by 26.8% (95% CI -40.5% to -13.1%) in Lambeth and Lewisham compared to Southwark. CONCLUSIONS: The Lambeth and Lewisham MECS demonstrates clinical effectiveness, reduction in hospital attendances and high patient satisfaction and represents a successful collaboration between commissioners, local HES units and primary healthcare providers.


Subject(s)
Community Health Services , Delivery of Health Care , Eye Diseases/diagnosis , Optometry , Patient Satisfaction , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Eye Diseases/therapy , Female , Humans , Infant , Male , Middle Aged , Ophthalmology , Referral and Consultation , State Medicine , United Kingdom , Young Adult
3.
BMJ Open ; 4(5): e004781, 2014 May 29.
Article in English | MEDLINE | ID: mdl-24875489

ABSTRACT

OBJECTIVES: To explore the views of optometrists, general practitioners (GPs) and ophthalmologists regarding the development and organisation of community-based enhanced optometric services. DESIGN: Qualitative study using free-text questionnaires and telephone interviews. SETTING: A minor eye conditions scheme (MECS) and a glaucoma referral refinement scheme (GRRS) are based on accredited community optometry practices. PARTICIPANTS: 41 optometrists, 6 ophthalmologists and 25 GPs. RESULTS: The most common reason given by optometrists for participation in enhanced schemes was to further their professional development; however, as providers of 'for-profit' healthcare, it was clear that participants had also considered the impact of the schemes on their business. Lack of fit with the 'retail' business model of optometry was a frequently given reason for non-participation. The methods used for training and accreditation were generally thought to be appropriate, and participating optometrists welcomed the opportunities for ongoing training. The ophthalmologists involved in the MECS and GRRS expressed very positive views regarding the schemes and widely acknowledged that the new care pathways would reduce unnecessary referrals and shorten patient waiting times. GPs involved in the MECS were also very supportive. They felt that the scheme provided an 'expert' local opinion that could potentially reduce the number of secondary care referrals. CONCLUSIONS: The results of this study demonstrated strong stakeholder support for the development of community-based enhanced optometric services. Although optometrists welcomed the opportunity to develop their professional skills and knowledge, enhanced schemes must also provide a sufficient financial incentive so as not to compromise the profitability of their business.


Subject(s)
Attitude of Health Personnel , Community Health Services/organization & administration , General Practice , Ophthalmology , Optometry , England , Humans , Qualitative Research , Referral and Consultation , Surveys and Questionnaires
4.
Eye (Lond) ; 24(9): 1509-14, 2010 Sep.
Article in English | MEDLINE | ID: mdl-20467448

ABSTRACT

PURPOSE: To develop a competency framework, using a modified Delphi methodology, for optometrists with a specialist interest in glaucoma, which would provide a basis for training and accreditation. METHODS: A modified iterative Delphi technique was used using a 16-member panel consisting almost exclusively of sub-specialist optometrists and ophthalmologists. The first round involved scoring the relevance of a draft series of competencies using a 9-point Likert scale with a free-text option to modify any competency or suggest additional competencies. The revised framework was subjected to a second round of scoring and free-text comment. The Delphi process was followed by a face-to-face structured workshop to debate and agree the final framework. The version of the framework agreed at the workshop was sent out for a 4-month period of external stakeholder validation. RESULTS: There was a 100% response to round 1 and an 94% response to round 2. All panel members attended the workshop. The final version of the competency framework was validated by a subsequent stakeholder consultation and contained 19 competencies for the diagnosis of glaucoma and 7 further competencies for monitoring and treatment. CONCLUSIONS: Application of a consensus methodology consisting of a modified Delphi technique allowed the development of a competency framework for glaucoma specialisation by optometrists. This will help to shape the development of a speciality curriculum and potentially could be adapted for other healthcare professionals.


Subject(s)
Clinical Competence , Glaucoma , Optometry/education , Specialization , Accreditation , Delphi Technique , Education, Medical, Continuing/organization & administration , Humans
5.
Br J Ophthalmol ; 93(4): 492-6, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19060011

ABSTRACT

AIMS: Standardised patient (SP) methodology is the gold standard for evaluating clinical practice. We investigated the content of optometric eyecare for an early presbyopic SP of African racial descent, an "at-risk" patient group for primary open-angle glaucoma (POAG). METHODS: A trained actor presented unannounced as a 44-year-old patient of African racial descent, complaining of recent near vision difficulties, to 100 community optometrists for an audio-recorded eye examination. The eye examinations were subsequently assessed via a checklist based on evidence-based POAG reviews, clinical guidelines and expert panel opinion. RESULTS: Ninety-five per cent of optometrists carried out optic disc assessment and tonometry, which conforms to the UK College of Optometrists' advice that those patients aged >40 years should receive at least two of the following tests: tonometry, optic disc assessment, visual field testing. Thirty-five per cent of optometrists carried out all of these tests and 6% advised the SP of increased POAG risk in those of African racial descent. CONCLUSION: SP encounters are an effective measure of optometric clinical practice. As in other healthcare disciplines, there are substantial differences between optometrists in the depth of their clinical investigations, challenging the concept of a "standard sight test". There is a need for continuing professional development (CPD) in glaucoma screening, in which the increased risk of POAG in those of African racial descent should be emphasised.


Subject(s)
Black People , Glaucoma, Open-Angle/diagnosis , Optometry/standards , Presbyopia/etiology , Adult , Community Health Services/methods , Community Health Services/standards , Diagnostic Techniques, Ophthalmological/standards , Early Diagnosis , England , Glaucoma, Open-Angle/complications , Glaucoma, Open-Angle/ethnology , Humans , Medical History Taking/standards , Ophthalmoscopy/statistics & numerical data , Optometry/methods , Patient Simulation , Practice Guidelines as Topic , Presbyopia/ethnology , Risk Factors , Tonometry, Ocular/statistics & numerical data
6.
Br J Ophthalmol ; 92(2): 225-30, 2008 Feb.
Article in English | MEDLINE | ID: mdl-17962396

ABSTRACT

BACKGROUND: The binocular Esterman visual field test (EVFT) is the current visual field test for driving in the UK. Merging of monocular field tests (Integrated Visual Field, IVF) has been proposed as an alternative for glaucoma patients. AIMS: To examine the level of agreement between the EVFT and IVF for patients with binocular paracentral scotomata, caused by either ophthalmological or neurological conditions, and to compare outcomes with useful field of view (UFOV) performance, a test of visual attention thought to be important in driving. METHODS: 60 patients with binocular paracentral scotomata but normal visual acuity (VA) were recruited prospectively. Subjects completed and were classified as "pass" or "fail" for the EVFT, IVF and UFOV. RESULTS: Good agreement occurred between the EVFT and IVF in classifying subjects as "pass" or "fail" (kappa = 0.84). Classifications disagreed for four subjects with paracentral scotomata of neurological origin (three "passed" IVF yet "failed" EVFT). Mean UFOV scores did not differ between those who "passed" and those who "failed" both visual field tests (p = 0.11). Agreement between the visual field tests and UFOV was limited (EVFT kappa = 0.22, IVF kappa 0.32). CONCLUSIONS: Although the IVF and EVFT agree well in classifying visual fields with regard to legal fitness to drive in the UK, the IVF "passes" some individuals currently classed as unfit to drive due to paracentral scotomata of non-glaucomatous origin. The suitability of the UFOV for assessing crash risk in those with visual field loss is questionable.


Subject(s)
Automobile Driving/standards , Scotoma/physiopathology , Visual Fields , Adult , Aged , Aged, 80 and over , Automobile Driving/legislation & jurisprudence , Humans , Middle Aged , Prospective Studies , Psychophysics , Reproducibility of Results , Scotoma/pathology , Vision Tests/methods , Visual Acuity
7.
Ophthalmology ; 108(12): 2358-68, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11733285

ABSTRACT

OBJECTIVE: To investigate the relationship between the absolute area of certain optic disc parameters and a number of ocular dimensional characteristics and demographic factors in young, healthy subjects. DESIGN: Cross-sectional study. PARTICIPANTS: One hundred twenty-one subjects, aged 16.5 to 35.4 years participated, encompassing a wide range of refractive error from +4 diopters (D) to -25.75 D. One eye from each subject was randomly selected for examination. MAIN OUTCOME MEASURES: Absolute size of the optic disc parameters: optic disc area (DA), neuroretinal rim area (NRA), optic cup area (CA), and peripapillary atrophy area (PA). METHODS: Absolute sizes of optic disc parameters were determined from digitized photographic color transparencies, taking into consideration the magnification of the fundus camera and human eye. Relationships between the absolute size of the optic disc features and axial length, crystalline lens thickness, anterior chamber depth, ocular refraction, front surface keratometry, age, and gender were examined. RESULTS: Axial length, lens thickness, front surface keratometry, and age demonstrated positive associations with all optic disc parameters, and anterior chamber depth and ocular refraction demonstrated negative associations in all cases. Multiple regression analysis revealed that the associations observed univariately for age, anterior chamber depth, lens thickness, front surface keratometry, and ocular refraction were confounded by axial length for all disc parameters. After taking logs, DA and NRA exhibit an exponential relationship with axial length, whereas PA and CA exhibit a linear relationship with axial length. DA and NRA increase by approximately 3% per millimeter increase in axial length at 20 mm and up to 40% for DA and 50% for NRA at an axial length of 35 mm. PA and CA are estimated to increase by 26% (10%-44%) and 10% (5%-16%), respectively, per millimeter increase in axial length. Females have approximately 5% smaller DA and 7% smaller NRA than males, but these effects are not statistically significant (P > 0.2). From the multiple regression analysis, females have 31% larger optic cup areas (1%-57%, P = 0.03) and 24% smaller PA (42% smaller to 5% larger P = 0.06) than males, but these effects are of borderline statistical significance at 5%. CONCLUSIONS: Of the ocular biometric factors considered, axial length seems to be the most important predictor of the absolute area of the optic disc parameters. No association exists between any disc parameter and age in this sample of subjects less than 40 years of age. Females exhibited smaller values for DA, NRA, and PA than did males, differences that were not statistically significant, and larger CA (P = 0.03).


Subject(s)
Optic Disk/anatomy & histology , Adolescent , Adult , Biometry/methods , Cross-Sectional Studies , Female , Humans , Male , Nonlinear Dynamics , Photography , Random Allocation , Reference Values , Sex Factors
9.
Graefes Arch Clin Exp Ophthalmol ; 237(2): 117-24, 1999 Feb.
Article in English | MEDLINE | ID: mdl-9987628

ABSTRACT

BACKGROUND: A study was carried out to ascertain, in ophthalmologically normal subjects, the short-term effects of dipivefrin hydrochloride 0.1% on visual performance and make comparisons with pilocarpine. METHODS: Twelve normal volunteers aged 20-26 years attended on three occasions. One eye, randomly selected, received one drop of either pilocarpine 2%, dipivefrin or saline 0.9%. High- and low-contrast LogMAR acuity at 6 m and pupil diameter (measured by infra-red pupillometry) were recorded at baseline (T0) and at intervals up to 90 min following instillation of drops. Program 30-2 of the Humphrey Visual Field Analyzer (HFA) was run at T0 and at 60 min after treatment instillation (T60). Saline was always instilled at visit 1, to allow for learning effects. On visits 2 and 3 either pilocarpine or dipivefrin was randomly instilled into the treated eye. RESULTS: Pilocarpine significantly worsened the field global indices mean deviation (P < 0.001) and pattern standard deviation (P < 0.01) compared with T0. There was no significant change with dipivefrin. A significant (P = 0.01) pupil dilation from 5.44 mm (SD 0.79) at T0 to 6.19 mm (SD 1.09) at T90 occurred with dipivefrin. Pilocarpine caused significant miosis. No significant changes in LogMAR values were found with dipivefrin. Pilocarpine significantly (P < 0.01) increased LogMAR values (i.e. reduced acuity) compared with dipivefrin. At T30 the mean increase in LogMAR was 0.76 (SD 0.30) for high and 0.83 (SD 0.11) for low contrast. By T90 recovery of acuity was virtually complete. CONCLUSIONS: In normals dipivefrin causes mydriasis but does not affect the central visual field global indices (as assessed by STATPAC), or high- and low-contrast LogMAR acuity. Pilocarpine adversely affects the visual field and both measures of acuity. Knowledge of these effects is of value in glaucoma therapy and when monitoring the progression of visual loss.


Subject(s)
Epinephrine/analogs & derivatives , Miotics/pharmacology , Mydriatics/pharmacology , Pilocarpine/pharmacology , Pupil/drug effects , Visual Acuity/drug effects , Visual Fields/drug effects , Adult , Cross-Over Studies , Double-Blind Method , Epinephrine/administration & dosage , Epinephrine/pharmacology , Female , Humans , Male , Miotics/administration & dosage , Mydriatics/administration & dosage , Ophthalmic Solutions/administration & dosage , Ophthalmic Solutions/pharmacology , Pilocarpine/administration & dosage , Visual Field Tests
10.
Ophthalmology ; 105(12): 2186-92, 1998 Dec.
Article in English | MEDLINE | ID: mdl-9855145

ABSTRACT

OBJECTIVE: To compare the magnification properties of 11 different fundus cameras (including 1 stereo fundus camera), a Rodenstock (infrared) scanning laser ophthalmoscope (SLO), the Heidelberg Laser Tomographic Scanner (LTS), and the Heidelberg Retina Tomograph (HRT). DESIGN: A cross-sectional study of the relationship between the true size of a fundus feature and its photographic-computer image in 14 different fundus imaging devices. This relationship was evaluated for each instrument using a model eye adjusted for axial ametropia between +11 diopter (D) and -14 D. To simulate refractive ametropia, the "crystalline lens" was removed to render the model eye aphakic, and the axial length was adjusted to give aphakic ametropia from emmetropia to +20 D. MAIN OUTCOME MEASURES: A correction factor (p) was calculated for each instrument, which can be used in calculations for determining true retinal size. RESULTS: The following were found to be of telecentric construction, Zeiss Oberkochen (WS240 Heidelberg), Zeiss Oberkochen (UK), Zeiss Oberkochen (Cologne), Nikon NF505, Kowa RCXV, SLO prototype (UK), LTS, and the HRT, and each exhibited a constant relationship between p and degree of ametropia of the model eye. The Canon CF6OU, Canon CF6OS, Canon CR4-45NM, Nidek 3-DX, Olympus GRCW, and Carl Zeiss Jena Retinophot were found not to be telecentric and exhibited a linear relationship between p and degree of ametropia of the model eye. For all instruments, p remained unchanged for axial and refractive ametropias of the same degree. CONCLUSIONS: The study has shown that not all fundus imaging systems are telecentric, so the use of a single magnification correction value may not be appropriate. These findings have important implications for the way in which true retinal size calculations are performed. Examples are given to show how the tabulated values of correction factors can be used for both telecentric and nontelecentric cameras in image size calculations.


Subject(s)
Fundus Oculi , Ophthalmology/instrumentation , Photography/standards , Humans , Models, Anatomic , Photography/instrumentation
11.
Ophthalmic Physiol Opt ; 18(2): 97-102, 1998 Mar.
Article in English | MEDLINE | ID: mdl-9692028

ABSTRACT

Ophthalmic drugs, both diagnostic and therapeutic, play a central role in new developments in optometry, particularly as practitioners extend their involvement in primary care. Optometrists now dilate more patients in routine practice, and this brings increasing concern about the risk of provoking acute closed angle glaucoma (CAG) attacks. It would seem that the risk of inducing acute CAG is far outweighed by the potential benefit of examining the eye through a dilated pupil. Driving difficulties, reported subjectively to be the result of glare, are frequently encountered by patients after dilation, and advice from the College of Optometrists is welcomed. The local anaesthetic proxymetacaine 0.5% is now marketed in the UK in preservative-free unit-dose applicators both alone and in combination with fluorescein, and is a more comfortable alternative to existing anaesthetics in unit-dose form. The second half of this paper includes a summary of the background to recent developments, as the UK profession takes its first steps towards the use of ocular therapeutic agents. Finally, some exciting new therapeutic preparations for use in the treatment of glaucoma, allergic eye disease, and dry eye conditions are discussed.


Subject(s)
Anesthetics, Local/therapeutic use , Miotics/therapeutic use , Mydriatics/therapeutic use , Conjunctivitis, Allergic/drug therapy , Dry Eye Syndromes/drug therapy , Glaucoma/drug therapy , Humans , Mydriatics/adverse effects , Ophthalmic Solutions/therapeutic use
12.
Ophthalmic Physiol Opt ; 18(2): 197-203, 1998 Mar.
Article in English | MEDLINE | ID: mdl-9692043

ABSTRACT

The rising mean age of our population has increased the need for understanding the physiologic consequences of ageing on visual function. Changes due to age were evaluated using a new scatter test implemented on the P_SCAN 100 pupillometer apparatus (Barbur, 1991). The test yields the full scatter function of the eye and also permits simultaneous measurement of pupil size (Barbur et al., 1995). In addition, contrast sensitivity was measured using sine wave gratings. The 28 subjects had a spherical refractive error between +0.50 DS and -0.25 DS, and astigmatism of less than -0.50 DC, V.A. of at least 6/6, and were ophthalmologically normal. To facilitate statistical analysis, subjects were classified into five groups according to age. For younger subjects (under 45 years), k', the integrated straylight parameter, varied little with age. For this group, k' ranged from 4.9 to 8.1. For subjects aged over 45 years, k' increased with age, ranging from 10.7 to 19.7. One way analysis of variance showed Group 5 (60 year olds) to have significantly greater k' than 20, 30, 40 and 50 year olds (P = 0.000). A slight downward shift in the contrast sensitivity function was seen over the age of 45. Significant differences between older and younger subjects were found at spatial frequencies of 3, and 10 cpd (P = 0.081, P = 0.002, respectively). Pupil diameter was found to reduce with age, but there was no significant difference between groups. Therefore, above 45 years, the ageing eye reveals a more rapid increase in forward scatter, and a reduction in contrast sensitivity, despite apparently good visual acuity.


Subject(s)
Aging/physiology , Lens, Crystalline/physiology , Scattering, Radiation , Adolescent , Adult , Analysis of Variance , Contrast Sensitivity , Humans , Light , Middle Aged , Pupil
13.
Ophthalmic Physiol Opt ; 18(5): 393-400, 1998 Sep.
Article in English | MEDLINE | ID: mdl-10023471

ABSTRACT

Several topical ocular local anaesthetics are available in preservative-free unit-dose applicators. There is little comparative data as to the efficacy and tolerability of these drugs. The purpose of this study was to compare the tolerability, and the depth and duration of corneal anaesthesia following instillation of one drop of 0.4% oxybuprocaine (benoxinate), 0.5% amethocaine, or 0.5% proxymetacaine. The tolerability of each anaesthetic was assessed using a linear ten point arbitrary comfort scale. A group of 14 healthy male subjects, with a wide variation in iris pigment levels, participated in the study (mean age 26.6 years, range 18-40 years). Corneal sensitivity was measured using a slit-lamp mounted Cochet-Bonnet aesthesiometer prior to instillation, and at 1, 2, 5, 10, 15, 20 and 30 min after instillation, and continued if necessary until corneal sensitivity had returned to pre-instillation levels. For each anaesthetic, complete anaesthesia occurred within 1 min of instillation and a return to baseline sensitivity levels occurred by 45 min. No significant difference in anaesthesia was found between the drugs at each time point. Tolerability profiles indicated that proxymetacaine was significantly better tolerated than either amethocaine (p < 0.01) or oxybuprocaine (benoxinate) (p < 0.001). There was considerable inter-subject variability in the duration of anaesthesia, and practitioners should be alert to this when allowing patients to leave the practice following the production of corneal anaesthesia. There seems little to choose clinically between the three active agents as regards clinical effectiveness. Proxymetacaine was significantly better tolerated than either amethocaine or oxybuprocaine.


Subject(s)
Anesthetics, Local/adverse effects , Cornea/drug effects , Ophthalmic Solutions/adverse effects , Administration, Topical , Adolescent , Adult , Anesthetics, Local/administration & dosage , Dose-Response Relationship, Drug , Female , Humans , Male , Ophthalmic Solutions/administration & dosage , Pain/prevention & control , Pain Measurement , Time Factors , Touch/drug effects
14.
Ophthalmology ; 104(3): 517-24, 1997 Mar.
Article in English | MEDLINE | ID: mdl-9082283

ABSTRACT

PURPOSE: The authors show how the predictive performance of a method for determining glaucomatous progression in a series of visual fields can be improved by first subjecting the data to a spatial processing technique. METHOD: Thirty patients with normal-tension glaucoma, each with at least ten Humphrey fields and 3.5 years of follow-up, were included. A linear regression model of sensitivity against time of follow-up determined rates of change at individual test locations over the first five fields (mean follow-up 1.46 years; standard deviation = 0.08) in each field series. Predictions of sensitivity at each location of the field nearest to 1 and 2 years after the fifth field were generated using these rates of change. Predictive performance was evaluated by the difference between the predicted and measured sensitivity values. The analysis was repeated using the same field data subjected to a spatial filtering technique used in image processing. RESULTS: Using linear modeling of the unprocessed field series, at 1 year after the fifth field, 72% of all predicted values were within +/- 5 dB of the corresponding measured threshold. This prediction precision improved to 83% using the processed data. At the 2-year follow-up field, the predictive performance improved from 56% to 73% with respect to the +/- 5 dB criterion. CONCLUSIONS: Predictions of visual field progression using a pointwise linear model can be improved by spatial processing without increased cost or patient time. These methods have clinical potential for accurately detecting and forecasting visual field deterioration in the follow-up of glaucoma.


Subject(s)
Glaucoma/physiopathology , Vision Disorders/physiopathology , Visual Fields/physiology , Adult , Aged , Aged, 80 and over , Cohort Studies , Disease Progression , Humans , Linear Models , Middle Aged , Predictive Value of Tests , Retrospective Studies , Sensitivity and Specificity , Visual Field Tests/statistics & numerical data
16.
Ophthalmic Physiol Opt ; 16(5): 416-29, 1996 Sep.
Article in English | MEDLINE | ID: mdl-8944186

ABSTRACT

Central visual fields were investigated by automated static perimetry, using programs 30-2 and 30-1 of the Humphrey Field Analyzer (HFA), in a group of healthy myopic individuals with peripapillary crescents and tigroid fundus changes only. Results were compared with 'non-myopic' and 'myopic subjects without crescents' control groups. The sample comprised 122 young, healthy volunteers between the ages of 18.5 and 35.4 years, free from any ocular or systemic disease, with refractive errors ranging from +4.00 to -25.75 D. Linear regression results are presented and may be useful in predicting the global indices mean deviation (MD) and mean sensitivity (MS), given either the axial length or ocular refraction, for medium and high myopes. Analysis of the HFA printouts revealed significantly depressed locations in all subject groups. However, locations identified at the 2, 1 and 0.5% probability levels were observed more frequently and more commonly in the myopes with peripapillary crescents than in the control groups. In this non-glaucomatous sample, four myopes had a borderline glaucoma hemifield test and two fell outside normal limits of this test. The superior hemifield, particularly the upper temporal quadrant, appeared to be most affected. Enlargement of the blind spot occurred in some subjects. Several possible explanations are suggested for the visual field sensitivity reduction in myopia.


Subject(s)
Myopia/physiopathology , Visual Field Tests , Visual Fields , Adolescent , Adult , Biometry , Case-Control Studies , Fundus Oculi , Humans
17.
Graefes Arch Clin Exp Ophthalmol ; 234(9): 553-60, 1996 Sep.
Article in English | MEDLINE | ID: mdl-8880153

ABSTRACT

BACKGROUND: Luminance, global motion and flicker sensitivities are affected in patients with primary open-angle glaucoma. Although no theoretical model has been put forward to explain the observed reduction in sensitivity in this patient group, these findings have often been attributed to diffuse and selective loss of large optic nerve fibres. METHODS: Movement processing was investigated using an optical projection system that generates smooth, continuous motion with control of speed, displacement and motion direction. Motion-displacement and direction-discrimination thresholds were measured in eight normal subjects and in three patients with diagnosed glaucoma. At each speed tested, targets were presented for a range of displacements and thresholds were extracted after probit analysis. The measurements were carried out both foveally and at 19 degrees in the periphery and provided the data necessary to develop and optimise a model of motion perception based on multiple time delays for the correlation of signals that map progressively more distant parts of the visual field. RESULTS: Our preliminary findings show that direction discrimination can be at chance level even for large displacements when motion is detected 80% of the time. Model simulations show that specific changes in the spatial sampling interval and the speed of transmission of the motion signals involved can cause the observed reduction in motion sensitivity and direction discrimination in patients with glaucoma. CONCLUSIONS: A model for motion detection and direction discrimination of single targets has been proposed to account for the measured functional relationship between motion displacement thresholds and target speed in normal subjects. Tested patients with glaucoma show reduced motion sensitivity and poor discrimination of motion direction. The type of degraded performance observed experimentally in glaucoma patients is also predicted by the model. Such predictions require specific changes in model parameters that may be indicative of changes in the retina caused by the disease.


Subject(s)
Glaucoma, Open-Angle/physiopathology , Motion Perception/physiology , Adult , Glaucoma, Open-Angle/complications , Humans , Middle Aged , Models, Theoretical , Sensory Thresholds
18.
19.
Ophthalmic Physiol Opt ; 15(5): 409-12, 1995 Sep.
Article in English | MEDLINE | ID: mdl-8524566

ABSTRACT

Central visual fields were investigated by automated static perimetry in a group of healthy myopic individuals with peripapillary crescents and tigroid fundus changes only. Results were compared with 'emmetropic' and 'myopic subjects without crescents' control groups. The sample comprised 122 young, healthy volunteers between the ages of 18.5 and 35.4 years, free from any ocular or systemic disease, with refractive errors ranging from +4.00 D to -25.75 D. Central visual fields were examined using programs 30-2 and 30-1 of the Humphrey Field Analyzer (HFA), which in combination yield a test point resolution of 4.2 degrees within the central 30 degrees. Visual field analysis showed a decline in the differential light sensitivity in myopes with peripapillary changes only, compared with the control groups. These field changes became more pronounced as the degree of myopia, axial length and area of the peripapillary crescent increased. Results suggest that the sensitivity decline of the central field occurs in subjects with axial lengths above 26 mm and more than 5 D of myopia. Knowledge of the likely field defects encountered in myopia will assist practitioners to distinguish between physiological and pathological fields in myopes.


Subject(s)
Myopia/physiopathology , Visual Fields/physiology , Adolescent , Adult , Analysis of Variance , Anthropometry , Eye/anatomy & histology , Humans , Refraction, Ocular , Visual Field Tests/methods , Visual Field Tests/statistics & numerical data
20.
Br J Ophthalmol ; 79(3): 207-12, 1995 Mar.
Article in English | MEDLINE | ID: mdl-7703195

ABSTRACT

BACKGROUND: Computerised perimetry is of fundamental importance in assessing visual function. However, visual fields are subject to patient response variability which limits the detection of true visual loss. METHODS: A method of improving the repeatability of visual field data was demonstrated by applying techniques used in image processing. An illustrative sample of nine normals and nine patients with field loss was used. Two successive Humphrey fields were selected for each subject. Repeatability was defined as the standard deviation of the pointwise differences between sensitivity values of the reference field and repeat field. The field data were then separately subjected to Gaussian and median image processing filters and the repeatability was compared with the unprocessed field results. RESULTS: Improvement in repeatability, by a factor of approximately 2, was demonstrated by both processes. CONCLUSION: These techniques may improve the reliable detection of loss of visual function using computerised perimetry.


Subject(s)
Glaucoma/diagnosis , Image Processing, Computer-Assisted/methods , Vision Disorders/diagnosis , Visual Field Tests/methods , Visual Fields , Adult , Case-Control Studies , Humans , Intraocular Pressure , Middle Aged , Reproducibility of Results
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