Extramedullary hematopoiesis in the facial sinus in a patient homozygous for Hemoglobin Lepore: the first case in literature.

Extramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside the bone marrow. The most affected areas are paravertebral ones. We report the case of a patient with homozygous Hb Lepore, not regularly transfused since the age of four years until the age of 29 years, when paravertebral heterotopic masses were first observed. After about 10 years she started reporting clinical signs suggestive of sinusitis. Computed tomography (CT) and Magnetic Resonance Imaging (MRI) showed heterotopic masses in the ethmoid and in the frontal sinuses. Involvement of the sinuses of the large facial area represents a rare localization of EMH. Various cases have been reported in patients with thalassemia intermedia, but no case has been reported with HbLepore. The diagnostic gold standard is MRI, which provides highly accurate and clear images. The treatment is based on hydroxyurea and/or an intensive transfusional regime and sometimes on surgery.

Morphologic and Pathometric Characterization of the Asian Soybean Rust (Phakopsora pachyrhizi) on Kudzu (Pueraria lobata) in Argentina.

Asian soybean rust (ASR) is a very important disease caused by Phakopsora pachyrhizi. The disease has emerged as a major threat to soybean production in South America since 2001. During the 2003-2004 growing season, P. pachyrhizi spread rapidly throughout most soybean-growing areas of northwestern and northeastern Argentina (1). One widespread naturalized host in the northeastern part of the country is kudzu (Pueraria lobata). Plants of severely infected kudzu were sampled during January 2005 in Cerro Azul (29°29'S Misiones Province) to quantify P. pachyrhizi infection and morphologically characterize the fungus in leaves. The number of lesions, uredinia per cm2, and uredinia per lesion were recorded from the undersides of 50 leaflets that were visually showing rust symptoms. The average number of lesions and uredinia per cm2 was 14 (4 to 22), and 24 (5 to 78), respectively. The number of uredinia per lesion was 3 (1 to 10). Twenty leaflets from the lower canopy averaged 55 (42 to 78) uredinia per cm2. The average size of urediniospores was 18.4 µm wide (12.5 to 22.5) and 22.7 µm long (17.5 to 26.3). Although important epidemics of ASR have not been registered on soybean crops in January (2) because of adverse conditions, the fungus was observed on kudzu plants. To our knowledge, this is the first report of morphologic and pathometric characterization of P. pachyrhizi on kudzu in Argentina. References: (1) M. A. Carmona et al Plant Dis. 89:109, 2005. (2) SINAVIMO, Sistema Nacional Argentino de Vigilancia y Monitoreo de plagas. Roya de la soja: Resultados de la campaña 2004-2005. On-line publication. SENASA, 2005.