ABSTRACT
Kidney transplantation is the optimal therapeutic approach for individuals with end-stage kidney disease. The Scientific Registry of Transplant Recipients has reported a continuous rise in the total number of kidney transplants performed in the United States, with 25,500 new kidney recipients in 2022 alone. Despite an improved glomerular filtration rate, the post-transplant period introduces a unique set of electrolyte abnormalities that differ from those encountered in chronic kidney disease. A variety of factors contribute to the high prevalence of hypomagnesemia, hyperkalemia, metabolic acidosis, hypercalcemia, and hypophosphatemia seen after kidney transplantation. These include the degree of allograft function, immunosuppressive medications and their diverse mechanisms of action, and metabolic changes after transplant. This article aims to provide a comprehensive review of the key aspects surrounding the most commonly encountered electrolyte and acid-base abnormalities in the post-transplant setting.
Subject(s)
Acid-Base Imbalance , Kidney Transplantation , Humans , Kidney Transplantation/adverse effects , Acid-Base Imbalance/etiology , Kidney Failure, Chronic/surgery , Water-Electrolyte Imbalance/etiology , Acidosis/metabolism , Acidosis/etiology , Hyperkalemia/etiology , Postoperative Complications/etiology , Hypercalcemia/etiology , Hypercalcemia/blood , Hypophosphatemia/etiology , Hypophosphatemia/epidemiology , Immunosuppressive Agents/therapeutic use , Immunosuppressive Agents/adverse effectsABSTRACT
Renal artery aneurysms (RAA) are rare and challenging to repair. We present a case of a 48-year-old female with solitary right kidney who had complex aneurysms near the renal hilum. CT angiogram showed fibromuscular dysplasia (FMD) features of the renal artery and 2 saccular aneurysms measuring 2.3 cm and 1 cm. An additional small lower pole renal artery added to the complexity of the case. Ex-vivo aneurysm repair was performed after the kidney was removed and flushed with preservation solution. This was followed by auto-transplantation to the right external iliac vessels. The patient did well postoperatively without need for dialysis with serum creatinine returning to normal 5 weeks after.