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3.
Vopr Onkol ; 38(2): 160-6, 1992.
Article in Russian | MEDLINE | ID: mdl-1300700

ABSTRACT

An analysis was carried out of chromosomal site-fragility in patients with primary multiple tumors and familial breast cancer. A possible correlation is discussed between fragile sites, breakpoints in chromosome rearrangements in cancer patients and the localization of oncogenes mapped in chromosomal regions involved in said rearrangements.


Subject(s)
Breast Neoplasms/genetics , Chromosome Fragility , Neoplasms, Multiple Primary/genetics , Breast Neoplasms/blood , Cells, Cultured/ultrastructure , Chromosome Aberrations , Chromosome Fragile Sites , Female , Genetic Markers , Humans , Lymphocytes/ultrastructure , Neoplasms, Multiple Primary/blood
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