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Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation.
Rosow, L; Jiang, J X; Deuel, T; Lechpammer, M; Zamani, A A; Milner, D A; Folkerth, R; Marty, F M; Kesari, S.
Transpl Infect Dis ; 13(4): 419-23, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21323827

ABSTRACT

Phaeohyphomycosis is an increasingly recognized cause of brain abscess in both immunocompetent and immunocompromised hosts. We report a case of cerebral phaeohyphomycosis in a 55-year-old male heart transplant recipient caused by Bipolaris spicifera. We review the literature regarding the pathogenesis, epidemiology, diagnosis, and management of infections with dematiaceous fungi.


Subject(s)
Ascomycota/isolation & purification , Brain Abscess/microbiology , Cerebral Phaeohyphomycosis/microbiology , Heart Transplantation/adverse effects , Mycoses/microbiology , Antifungal Agents/therapeutic use , Ascomycota/classification , Ascomycota/drug effects , Brain Abscess/diagnostic imaging , Brain Abscess/drug therapy , Cerebral Phaeohyphomycosis/diagnostic imaging , Cerebral Phaeohyphomycosis/drug therapy , Humans , Immunocompromised Host , Magnetic Resonance Imaging , Male , Middle Aged , Mycoses/diagnostic imaging , Mycoses/drug therapy , Pyrimidines/therapeutic use , Radiography , Treatment Outcome , Triazoles/therapeutic use , Voriconazole
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