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1.
Eur J Health Econ ; 19(6): 821-830, 2018 Jul.
Article in English | MEDLINE | ID: mdl-28823011

ABSTRACT

The national guidelines for treatment of chronic coronary heart disease (CHD) recommend surgical coronary aortic bypass grafting (CABG) rather than percutaneous coronary intervention (PCI) for patients with a coronary three-vessel disease. The epidemiology of three-vessel CHD and data about the application of different revascularisation strategies raise suspicion of deviation from the guidelines in the treatment of those patients. Claims data containing records of almost 10 million patients of the largest German statutory health insurance fund (Techniker Krankenkasse) were utilised to measure adherence to the guidelines for treatment of groups of patients with one-, two-, and three-vessel CHD, respectively. The impact of age, sex, and comorbidity on each patient's revascularisation procedure was investigated as well. There was no significant difference in the rate of PCI between the groups. In conclusion, the hypothesis that patients with a coronary three-vessel disease are not always treated according to the recommendations of the national guidelines could not be disproved by this study. Finally, the results of this study suggest that the best revascularisation strategy for each patient with two- and three-vessel disease should be decided upon by an interdisciplinary discussion between both cardiologists and cardiac surgeons.


Subject(s)
Coronary Artery Bypass , Coronary Artery Disease/therapy , Percutaneous Coronary Intervention , Practice Guidelines as Topic , Aged , Female , Humans , Insurance Claim Review , Male , Stents , Treatment Outcome
3.
Dtsch Med Wochenschr ; 141(10): e96-e103, 2016 May.
Article in German | MEDLINE | ID: mdl-27176071

ABSTRACT

UNLABELLED: Background and Problem: Acute nonspecific back pain disorders are typically self-limiting. According to the national guideline low back pain, only in case of clinical suspicion of a serious course radiological imaging should take place immediately. Otherwise, the guideline recommends waiting at least six weeks. PATIENTS AND METHODOLOGY: Using Statutory Health Insurance (SHI) routine data of the Techniker Krankenkasse we analyzed how many of the insured persons suffering from acute back pain for the first time with no indication of a serious outcome received a non-indicated diagnostic imaging. RESULTS: In about 10 % diagnostic imaging is conducted after initial diagnosis. If an imaging is carried out, roughly one third of these cases takes place ahead of time or is completely unnecessary. Methodically this is a very conservative estimation, thus it seems likely that the extent of overdiagnosis in actual medical care situation is even larger. CONCLUSIONS: Every third patient who received radiological diagnostics due to first acute nonspecific back pain underwent the procedure more quickly than recommended (less than six weeks). Overdiagnosis is not only economically problematic but also with respect to patient orientation and patient safety. It may cause substantial damage to patients - either by the use of diagnostics itself or by means of therapies initiated after diagnostics.


Subject(s)
Back Pain/diagnostic imaging , Medical Overuse/statistics & numerical data , Quality Assurance, Health Care/statistics & numerical data , Back Pain/economics , Back Pain/etiology , Back Pain/therapy , Costs and Cost Analysis , Diagnosis, Differential , Germany , Guideline Adherence , Humans , Medical Overuse/economics , National Health Programs/economics , Quality Assurance, Health Care/economics , Watchful Waiting
4.
Gesundheitswesen ; 78(S 01): e135-e144, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27056711

ABSTRACT

Background: Guidelines have special importance in medicine, however, it is questionable to what extent these recommendations are applied in daily care, and under which conditions claims data can be used for verification of guideline adherence. Method: Advantages and limitations of claims data for verification of guidelines compliance in the therapeutic area as well as the guidelines themselves were analysed and critically assessed. To substantiate these results, claims data of a major German health insurance fund (Techniker Krankenkasse) were analysed. Results: 104 236 patients were identified. With certain limitations, claims data are useful for verifying guideline adherence; it could be shown that in pharmacotherapy the beta-adrenergic receptor blocker was used to the highest extent (70.5%). In contrast, only 56.4% of patients were treated with pure ACE inhibitors and ACE combined preparation. Conclusion: In order to validate guideline adherence by means of claims data analyses, a number of conditions relating to the database, the therapeutic area and the guidelines themselves have to be considered. Guideline recommendations, which, for example, are based on clinical data, cannot be reviewed by using claims data. Despite these limitations, claims data provide a suitable tool for reviewing selected guideline recommendations. They show that the current use of pharmacotherapy as well as clinical and diagnostic interventions might be increased in accordance with the guideline recommendations.

5.
Herz ; 41(7): 614-624, 2016 Nov.
Article in German | MEDLINE | ID: mdl-26883900

ABSTRACT

BACKGROUND: The German national guidelines on chronic heart failure provide treatment recommendations to physicians and reflect the current level of evidence; however, it is questionable to what extent these recommendations are applied in the routine practice and what the effect of guideline adherence on mortality is. METHODS: In this study the claims data of a major German health insurance fund collected over a period of 4 years were analyzed. Using binary logistic regression and Cox regression analyses the influence of drug prescriptions, diagnostic measures, influenza vaccination, the New York Heart Association (NYHA) status, the age and gender on mortality were examined. RESULTS: The study population consisted of 85,465 heart failure patients. Approximately 60 % of the drugs were prescribed according to the guidelines. There was a positive correlation between a higher NYHA status and mortality with an odds ratio (OR) of 3.264. Especially pharmacotherapy with angiotensin-converting enzyme (ACE) inhibitors and beta blockers according to the guidelines was associated with a lower mortality rate (OR 0.448 resp. 0.444). Also patients diagnosed using echocardiography at regular intervals showed a lower risk of dying (OR 0.314). CONCLUSION: The results of this large sample could confirm the results of clinical trials that a therapy according to the guidelines has a significant impact on mortality. By analyzing the claims data evidence was found that in the treatment of heart failure patients the medical results could be improved by adherence to guideline recommendations.


Subject(s)
Cardiotonic Agents/therapeutic use , Echocardiography/standards , Guideline Adherence/statistics & numerical data , Heart Failure/mortality , Heart Failure/therapy , Practice Guidelines as Topic , Age Distribution , Aged , Aged, 80 and over , Cardiology/standards , Cardiotonic Agents/standards , Echocardiography/statistics & numerical data , Female , Germany/epidemiology , Guideline Adherence/standards , Heart Failure/diagnosis , Humans , Male , Middle Aged , Prevalence , Risk Factors , Sex Distribution , Survival Rate , Treatment Outcome
6.
Gesundheitswesen ; 78(7): e23-9, 2016 Jul.
Article in German | MEDLINE | ID: mdl-26695543

ABSTRACT

UNLABELLED: Backround and Objectives: Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed mental disorders in children and adolescents. The rate of persistence into adulthood varies up to 60% and shows the importance of the disease. Here we present age-stratified cost information on adult patients, as well as data on occupational therapy, medication and multimodal treatment. Furthermore, we also investigated retrospectively if methylphenidate was prescribed for adults already before its approval in 2011. METHODS: Claims data of a major German insurance fund (Techniker Krankenkasse) was available. Inclusion criteria were patients with ADHD diagnosis, either hospitalized or treated on an outpatient basis in 2006, 2007 and 2008 and insured over this period. This enabled identifying this disease as chronic. The data were analyzed as part of a control group design (1:3). Cost differences were examined as also the odds ratios for the burden of comorbidities and use of atomoxetine and methylphenidate. RESULTS: 77.9% of the identified ADHD patients were male (mean age: 16.5 years ±11.1). The mean total costs of patient treatment were € 2,032 (±4,112). The odds ratio was highest for the indication developmental disorders of scholastic skills (15.4) and differed between the sexes (female: 24.0 vs. male: 14.2). Drug prescription was higher in male than in female patients (atomoxetine: 7.2 vs. 5.9% and methylphenidate 59.1 vs. 48.4%). CONCLUSIONS: This study provides important insights into the importance of the adult ADHD collective. There were increasing resource consumption identified in adult ADHD patients. In addition, methylphenidate was used off-label for treating adults already before 2011 and its approval in 2011 provided increased certainty for physicians regarding prescription of this drug.


Subject(s)
Attention Deficit Disorder with Hyperactivity/drug therapy , Attention Deficit Disorder with Hyperactivity/economics , Central Nervous System Stimulants/economics , Central Nervous System Stimulants/therapeutic use , Drug Prescriptions/economics , Health Care Costs/statistics & numerical data , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Attention Deficit Disorder with Hyperactivity/epidemiology , Child , Child, Preschool , Female , Germany/epidemiology , Humans , Infant , Infant, Newborn , Male , Middle Aged , Pregnancy , Prevalence , Sex Distribution , Young Adult
7.
Gesundheitswesen ; 78(5): 298-305, 2016 May.
Article in German | MEDLINE | ID: mdl-26021371

ABSTRACT

BACKGROUND: Due to the insufficient data base the Federal Joint Committee (G-BA) had in 2009 after 7 years of deliberation decided to initiate consultation regarding ambulatory brachytherapy for localised prostate cancer for 10 years from social health insurance (SHI) benefits. The aim is to gain more findings by means of comparative studies. PROBLEM: Based on the non-availability of clinical primary data of a methodologically acceptable level, it was analysed to what extent secondary data of the SHI may be used in order to arrive at valid conclusions for benefit aspects. METHODS: As base approx. 8 million insured of TK with their data of cost reimbursement between 2006 and 2011 were considered. In SHI secondary data no clinical information regarding tumour stage and other prognostic factors are available. Therefore, a novel method with therapy-specific multisectoral inclusion and exclusion criteria, respectively, was developed in order to differentiate between localised and advanced tumours of the prostate. Overall survival, relapse-free survival, event-free survival and side-effects associated to prostate cancer were analysed. RESULTS: Out of 87 822 insured persons with the diagnosis prostate cancer, 795 with PBT, 10 936 with RP and 1 925 with EBRT were investigated in detail. The 4-year event-free survival rate was 73% for RP, 77% for PBT and 71% for EBRT. Many prostate cancer-specific side effects appeared already before intervention. Side effects of the intestinal tract (23.8%) and sexual impairments (26.5%) were more frequent for EBRT than for RP (17.1%/14.8%) and PBT (16.4%/13.2%). CONCLUSION: By means of SHI secondary data and adequate operationalisation important findings regarding relevant aspects of prostate cancer in healthcare research can be generated. However, these hold methodological limitations and are not suited to draw valid conclusions for benefit assessment. Based solely on SHI routine data valid statements regarding comparative benefit assessment are limited. Limitations could be reduced by applying a record linkage with clinical data. Such primary data should include information on tumour stages as well as therapy assignment and observation of survival time.


Subject(s)
Brachytherapy/economics , Insurance Benefits/economics , Insurance Coverage/economics , Prostatic Neoplasms/economics , Prostatic Neoplasms/radiotherapy , Radiation Injuries/economics , Adult , Aged , Cost-Benefit Analysis/economics , Disease-Free Survival , Germany/epidemiology , Health Care Costs/statistics & numerical data , Humans , Insurance Coverage/statistics & numerical data , Insurance, Health, Reimbursement/economics , Insurance, Health, Reimbursement/statistics & numerical data , Male , Middle Aged , National Health Programs/economics , National Health Programs/statistics & numerical data , Prostatic Neoplasms/mortality , Radiation Injuries/mortality , Retrospective Studies , Survival Rate
8.
Article in German | MEDLINE | ID: mdl-25708909

ABSTRACT

After an introduction to the theme with an overview of the implementation of the Disease Management Programs (DMP), accompanying documentation, present utilization and costs of the programs, the present article is primarily devoted to the issue of the analysis of the benefits of DMP. Following an assessment of the legally specified evaluation requirements, in the absence of a prospective, randomized, controlled trial (RCT), the results of three studies are first summarized, which, with the application of propensity score matching, utilize the routine data of the statutory health insurance schemes to form a control group. The overview concludes with a look at the planned changes in evaluation and the intended expansion of the DMP to programs for other chronic illnesses.


Subject(s)
Chronic Disease/economics , Chronic Disease/therapy , Delivery of Health Care/economics , Health Care Costs/statistics & numerical data , Health Services Accessibility/economics , Cost Control/legislation & jurisprudence , Cost-Benefit Analysis/economics , Cost-Benefit Analysis/legislation & jurisprudence , Delivery of Health Care/legislation & jurisprudence , Disease Management , Germany , Health Care Costs/legislation & jurisprudence , Health Services Accessibility/legislation & jurisprudence , Humans , Models, Economic , Organizational Objectives
9.
Gesundheitswesen ; 77 Suppl 1: S91-2, 2015 Sep.
Article in German | MEDLINE | ID: mdl-23549653

ABSTRACT

The aim of this study was to compare the effect of our newly developed online evidence-based patient information (EBPI) vs. standard patient information about subthreshold elevated blood glucose levels and primary prevention of diabetes on informed patient decision-making. EBPI significantly improved knowledge about elevated glucose levels, but also increased decisional conflict and critical attitudes to screening and treatment options. The intention to undergo metabolic screening decreased as a result.


Subject(s)
Consumer Health Information/methods , Decision Support Systems, Clinical/organization & administration , Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/prevention & control , Electronic Health Records/organization & administration , Preventive Medicine/methods , Biomarkers/blood , Blood Glucose/analysis , Data Mining/methods , Diabetes Mellitus, Type 2/blood , Evidence-Based Medicine , Female , Humans , Knowledge Bases , Male , Treatment Outcome , User-Computer Interface
10.
Dtsch Med Wochenschr ; 139(19): 983-9, 2014 May.
Article in German | MEDLINE | ID: mdl-24782150

ABSTRACT

BACKGROUND: Referring to the German PRISCUS list, the paper analyzes differences in the prescription of potentially inadequate medication (PIM) between older and younger patients. We account for changes in the development over time and for the influence of the publication of the PRISCUS list. METHODS: The retrospective study analyzes pharmaceutical prescriptions based on data from the Techniker Krankenkasse for the years 2008-20012. Age groups are compared regarding PIM prescriptions as share of total prescriptions within therapeutic areas (based on ATC codes). For a comparison of prescribed daily doses between age groups the median of those younger than 65 was indexed to the value 100. RESULTS: The share of older insured with at least one PRISCUS prescription declined from 21,7 % in 2008 to 18,9 % in 2012. Moreover, the total share of PIM prescriptions is steadily higher for elderly persons. Comparing major therapeutic areas shows a heterogeneous picture. An influence of the PRISCUS list on the prescription behavior is not observable. CONCLUSION: The share of PIM prescriptions in the TK sample is slightly declining over time. Unexpectedly, the total share is higher for the elderly than for those below 65. With regard to different therapeutic areas, results are less clear. For future research, our findings emphasize the need to rely on the applied methods.


Subject(s)
Frail Elderly , Inappropriate Prescribing/trends , Pharmacopoeias as Topic , Prescription Drugs/adverse effects , Aged , Cross-Sectional Studies , Drug Interactions , Drug Utilization/trends , Female , Germany , Humans , Inappropriate Prescribing/statistics & numerical data , Male , National Health Programs/statistics & numerical data , Polypharmacy , Retrospective Studies
11.
Gesundheitswesen ; 76(11): 735-41, 2014 Nov.
Article in German | MEDLINE | ID: mdl-24696370

ABSTRACT

OBJECTIVES: During the last decades patient and public involvement has gained more and more political approval. An important milestone regarding collective patient interests was the Statutory Health Insurance Modernisation Act in 2004 (§ 140 f SGB V). No systematic research has been conducted regarding the situation of patient representatives at the federal state level as yet. The aim of the following study is to close this gap, focusing on educational needs of patient representatives. METHODS: After screening the literature we identified and discussed relevant aspects of patient participation in a focus group of 7 patient representatives. Based on these findings a standardised questionnaire was developed in cooperation with scientists and patient representatives. We sent the written questionnaire to 504 patient representatives at the federal state level. The survey was targeted at patient representatives who currently participate or have in the past participated in a committee at federal state level according to § 140 f SGB V. RESULTS: A total of 184 completed questionnaires was returned for an overall response rate of 36.5%. Most respondents felt poorly prepared for their role and regard a compulsory preparation course as necessary. Patient representatives want to be an active part in the decision-making process of the committee meetings. They report educational needs on different topics and they are willing to close these gaps. For the future, patient representatives expect increasing significance of collective participation. CONCLUSION: The results can be used to develop educational programmes for patient representatives in order to qualify them for the best possible performance of their tasks. Furthermore the results can provide a scientific basis for political discussions and for reasoning capacity building of patient representatives.


Subject(s)
Needs Assessment/statistics & numerical data , Patient Advocacy/education , Patient Advocacy/statistics & numerical data , Patient Participation/statistics & numerical data , Germany , Health Care Surveys
12.
Cardiovasc Pathol ; 23(3): 160-8, 2014.
Article in English | MEDLINE | ID: mdl-24529701

ABSTRACT

INTRODUCTION: Our goal was to show that blunting of myocardial flow reserve is mainly involved in adaptive chronic myocardial hibernation without apparent cardiomyocyte degeneration. METHODS AND RESULTS: Sheep chronically instrumented with critical multivessel stenosis and/or percutaneous transluminal coronary angioplasty (PTCA)-induced revascularization were allowed to run and feed in the open for 2 and 5 months, respectively. Regional myocardial blood flow (MBF) with colored microspheres, regional and global left ventricular function and dimensions (2D echocardiography), and myocardial structure were studied. In sheep with a critical stenosis, a progressive increase in left ventricular end-diastolic and end-systolic cavity area and a decrease in fractional area change were found. Fraction of wall thickness decreased in all left ventricular wall segments. MBF was slightly but not significantly decreased at rest at 2 months. Morphological quantification revealed a rather small but significant increase in diffusely distributed connective tissue, cardiomyocyte hypertrophy, and presence of viable myocardium of which almost 30 % of the myocytes showed depletion of sarcomeres and accumulation of glycogen. The extent of myolysis in the transmural layer correlated with the degree of left ventricular dilation. Structural degeneration of cardiomyocytes was not observed. Balloon dilatation (PTCA) of one of the coronary artery stenoses at 10 weeks revealed recovery of fraction of wall thickness and near normalization of global subcellular structure at 20 weeks. CONCLUSION: These data indicate that chronic reduction of coronary reserve by itself can induce ischemic cardiomyopathy characterized by left ventricular dilatation, depressed regional and global function, adaptive chronic myocardial hibernation, reactive fibrosis and cardiomyocyte hypertrophy in the absence of obvious degenerative phenomena. SUMMARY: Reduction of myocardial flow reserve due to chronic coronary artery stenosis in sheep induces adaptive myocardial hibernation without involvement of degenerative phenomena.


Subject(s)
Coronary Circulation , Coronary Stenosis/therapy , Myocardial Stunning/therapy , Percutaneous Coronary Intervention , Animals , Chronic Disease , Coronary Stenosis/complications , Coronary Stenosis/pathology , Coronary Stenosis/physiopathology , Disease Models, Animal , Fibrosis , Hypertrophy, Left Ventricular/etiology , Hypertrophy, Left Ventricular/pathology , Hypertrophy, Left Ventricular/physiopathology , Myocardial Stunning/etiology , Myocardial Stunning/pathology , Myocardial Stunning/physiopathology , Severity of Illness Index , Sheep , Time Factors , Ventricular Dysfunction, Left/etiology , Ventricular Dysfunction, Left/pathology , Ventricular Dysfunction, Left/physiopathology , Ventricular Function, Left
13.
Public Health ; 128(3): 274-81, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24559770

ABSTRACT

OBJECTIVE: Failure of closure of the neural tube often leads to serious malformations, including spina bifida, anencephaly and encephalocoele. Despite improvements in medical and surgical treatment, the burden associated with spina bifida is substantial but country-specific data are lacking outside North America. This study aims to improve understanding of the economic implications and burden associated with the morbidity of children and adults with neural tube defects (NTDs) in Germany. STUDY DESIGN: Retrospective data analysis. METHODS: 2006-2009 German health insurance data of persons with NTDs (spina bifida and encephalocoele) were analysed to determine the economic burden of illness associated with NTDs in Germany. Cases were identified using ICD-10 codes; data included outpatient and inpatient care, rehabilitation, remedies and medical aids, pharmacotherapy use, long-term care and information on sick leave. The analysis was stratified by age group to provide a burden estimate specific to a person's age. To obtain an indicator of incremental burden to the Statutory Health Insurance (SHI), results were compared to the standardized healthcare expenditures according to the German Risk Compensation Scheme (RSA). RESULTS: Overall, 4141 persons with an ICD code related to NTDs were identified (out of a population of 7.28 million persons screened). The administrative prevalence ranged from 0.54 to 0.58 per 1000 enrollees. Of those, 3952 (95.4%) were diagnosed with spina bifida. The average annual mean healthcare expenditure of persons with spina bifida was €4532 (95% CI = 4375-4689, SD = 9590, Median = 1000), with inpatient care contributing €1358 (30.0%), outpatient care €644 (14.2%), rehabilitation €29 (0.6%), pharmacotherapy €562 (12.4%), and remedies and medical aids €1939 (42.8%). The incremental cost due to spina bifida was substantially higher than the standardized SHI expenditures for all age groups. The difference was highest for persons ≤ 10 years old (€10,971 vs €2360 for the age group ≤ 1, €8599 vs €833 for the age group 2-5 years and €10,601 vs €863 for the age group 6-10 years). The difference was smallest for the age group 41-50 years (€2524 vs €1101) and for 71 years and over (€5278 vs €4389). CONCLUSION: Expenditures of persons with spina bifida exceeded the standardized SHI expenditures, indicating a considerable economic burden. The economic burden is continuous throughout the person's life, with high monetary impact and exposure to the healthcare system (especially in early years of life). Efforts should be devoted to improve the prevention of NTDs and provide appropriate support for persons with NTDs, parents, and caregivers--especially in early years.


Subject(s)
Cost of Illness , Neural Tube Defects/economics , Adolescent , Adult , Aged , Child , Child, Preschool , Delivery of Health Care/economics , Female , Germany/epidemiology , Health Expenditures/statistics & numerical data , Humans , Infant , Insurance, Health/economics , International Classification of Diseases , Male , Middle Aged , Neural Tube Defects/epidemiology , Prevalence , Retrospective Studies , Young Adult
15.
Dtsch Med Wochenschr ; 139(1-2): 19-22, 2014 Jan.
Article in German | MEDLINE | ID: mdl-24062021

ABSTRACT

BACKGROUND AND AIM: The specific documentation for disease management programs (DMP) in Germany with respect to §â€Š137 Social Code Book V is the basis for evaluating the DMP. DMP run up costs of the order of a billion euro without assessing evidence-based benefit so far. Aim of this study was to question if and to which extent this documentation may be suitable for reliable quality assurance in its present form. METHODS: Data of nearly 300000 insured persons of a German Statutory Health Insurance (Techniker Krankenkasse, TK) which were continuously registered from July 1st 2009 until December 31st 2010 in a DMP were analyzed. We analyzed how items which were components of claims data and of DMP documentation were matched. RESULTS: With regard to prescriptions there were some considerable differences. Prescription of glibenclamid was documented twice as frequently in the DMP documentation compared to prescriptions filled in pharmacies. Only a fraction of emergency hospitalizations documented in the claims data were found in the DMP documentation. Investigations of the fundus oculi for diabetics are mentioned three times more frequently in the DMP documentation than they are accounted by ophthalmologists. CONCLUSION: There are considerable differences between claims data and DMP specific documentation. The latter shows a plainly reduced validity for investigated fields in the documentation forms. Reasons for this are manifold. Former evaluations of DM Ps carried out just on the basis of DMP documentation are thus highly questionable. Therefore, the DMPs themselves and their documentation have to be reformed.


Subject(s)
Chronic Disease/rehabilitation , Disease Management , Documentation/statistics & numerical data , Documentation/standards , National Health Programs/statistics & numerical data , Research Design/statistics & numerical data , Research Design/standards , Chronic Disease/epidemiology , Combined Modality Therapy , Evidence-Based Medicine , Germany , Humans , Life Style , Patient Admission/statistics & numerical data , Patient Satisfaction , Program Evaluation , Quality Assurance, Health Care/standards , Quality Assurance, Health Care/statistics & numerical data , Randomized Controlled Trials as Topic , Reproducibility of Results , Treatment Outcome
16.
Article in German | MEDLINE | ID: mdl-23455561

ABSTRACT

Claims data have proven useful for carrying out cost-of-illness studies. To avoid overestimating disease-related costs, only those costs that are related to a specific disease should be considered. The present study demonstrates two basic approaches for identifying disease-related costs. Using the example of attention-deficit hyperactivity disorder (ADHD), the advantages and drawbacks of expert-based approaches and those based on control groups are compared. Anonymized data from the "Techniker Krankenkasse" for 2008 were available for the study. The study population encompassed all ADHD patients and a control group that was five times bigger. Additionally, a systematic literature review was carried out on 65 relevant studies. Compared with the control group, disease-related costs were EUR 2,902 per ADHD patient on average. However, using the expert-based approach, costs were established to be EUR 923 lower. This is mainly because a comparison with an appropriate control group incorporates all costs for possible comorbidities and concomitant diseases. Both approaches have specific advantages and drawbacks, and when planning studies the respective limitations need to be considered.


Subject(s)
Attention Deficit Disorder with Hyperactivity/economics , Attention Deficit Disorder with Hyperactivity/epidemiology , Health Care Costs/statistics & numerical data , Insurance Benefits/economics , Insurance Benefits/statistics & numerical data , Insurance Claim Review , Models, Economic , Germany/epidemiology , Humans , Prevalence
17.
Dtsch Med Wochenschr ; 138(3): 69-75, 2013 Jan.
Article in German | MEDLINE | ID: mdl-23299340

ABSTRACT

BACKGROUND AND OBJECTIVE: Based on claims-data of 5.43 million members of a large German statutory health insurance fund in 2008 (Techniker Krankenkasse), the aim of this contribution is to update and more precisely quantify age- and gender-specific prevalence and incidence of type 2 diabetes mellitus (T2DM) in a German setting. METHODS: A patient was classified as T2DM prevalent if he or she had received at least two outpatient diagnoses of T2DM in two different quarters of the year and/or had received at least one T2DM diagnosis during inpatient treatment between 01/01/2006 and 12/31/2008. A patient was considered to have had new onset T2DM in 2008 under one of three conditions: 1. no diagnosis of T2DM in 2006 and 2007, 2. no presripction of oral antidiabetics in 2006 and 2007, 3. either one inpatient or two outpatient diagnoses of T2DM conducted in two different quarters of 2008 or one outpatient T2DM diagnosis in 2006/07 when the second diagnosis was made in 2008. RESULTS: A total of 254,524 patients had T2DM. Compared to the total membership of the medical insurance fund, the prevalence of T2DM was 4.69 %. The average age was 64.8 years, and 66.37 % were male. The incidence of T2DM in our sample was 2.814 cases per 1,000 person-years in men and 1.690 cases in 1,000 person-years in women. Based on our sample and on official population data, 4,704,585 patients (5.75 %) in Germany would be T2DM prevalent in 2009. The number of incident T2DM cases would amount to 215,746 patients (0.264 %). CONCLUSIONS: T2DM is one of the most common chronic diseases in Germany. The expected demographic changes in Germany will increase the burden on the German health system caused by T2DM.


Subject(s)
Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/epidemiology , Age Distribution , Female , Germany/epidemiology , Humans , Incidence , Male , Middle Aged , Prevalence , Risk Factors , Sex Distribution
18.
Gesundheitswesen ; 74(10): 605-11, 2012 Oct.
Article in German | MEDLINE | ID: mdl-22566164

ABSTRACT

BACKGROUND: The expectations of health services research are growing with its recognition and acceptance as an independent field within health research. What are the issues that health services research should deal with in future to perform the tasks it will be confronted with? Different health-care players like physicians, scientists, sponsors, and third-party payers were invited to give answers to these questions which was the aim of the workshop held in Cologne on the 8th November 2010. The IMVR (Institute for Medical Sociology, Health Services Research, and Rehabilitation Science, University of Cologne) and WINEG (Scientific Institute of TechnikerKrankenkasse for the Benefit and Efficiency in Health Care) jointly hosted the 'Expert Workshop - Future Issues of Health Services Research' in order to get closer to meeting this goal. METHODS: Experts met in 4 focus groups to identify the future issues of health services research in the one-day workshop in Cologne in November 2010. The participants discussed their proposed issues in a moderated session and decided on the key future issues of health services research in a double voting procedure. RESULTS: 36 experts accepted the invitation. Of these 6 were experts of the medical profession, 4 of the group of sponsors, 13 scientific experts and 13 experts of the groups of third-party payers. According to their rating, "intersectoral networking", "patients' preferences", and "the evaluation of innovations, processes, and methods" are the 3 key future issues of health services research. CONCLUSIONS: The experts developed the key future issues for health services research according to their opinion. They answered the question on the issues, health services research should be occupied with in future, i.e. a broad range of topics. To a certain extent, they returned to former issues and problems for which satisfactory solutions have not yet been found.


Subject(s)
Expert Testimony , Health Services Research/trends , National Health Programs/trends , Cooperative Behavior , Focus Groups , Forecasting , Germany , Health Services Needs and Demand/trends , Humans , Interdisciplinary Communication , Quality Improvement/trends
19.
Diabet Med ; 29(8): 1011-20, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22133040

ABSTRACT

AIMS: To compare the effect of our newly developed online evidence-based patient information vs. standard patient information about sub-threshold elevated blood glucose levels and primary prevention of diabetes on informed patient decision making. METHODS: We invited visitors to the cooperating health insurance company, Techniker Krankenkasse, and the German Diabetes Center websites to take part in a web-based randomized controlled trial. The population after randomization comprised 1120 individuals aged between 40 and 70 years without known diabetes, of whom 558 individuals were randomly assigned to the intervention group receiving evidence-based patient information, and 562 individuals were randomly assigned to the control group receiving standard information from the Internet. The primary endpoint was acquired knowledge of elevated blood glucose level issues and the secondary outcomes were attitude to metabolic testing, intention to undergo metabolic testing, decisional conflict and satisfaction with the information. RESULTS: Overall, knowledge of elevated glucose level issues and the intention to undergo metabolic testing were high in both groups. Participants who had received evidence-based patient information, however, had significantly higher knowledge scores. The secondary outcomes in the evidence-based patient information subgroup that completed the 2-week follow-up period yielded significantly lower intention to undergo metabolic testing, significantly more critical attitude towards metabolic testing and significantly higher decisional conflict than the control subgroup (n=466). Satisfaction with the information was not significantly different between both groups. CONCLUSIONS: Evidence-based patient information significantly increased knowledge about elevated glucose levels, but also increased decisional conflict and critical attitude to screening and treatment options. The intention to undergo metabolic screening decreased. Future studies are warranted to assess uptake of metabolic testing and satisfaction with this decision in a broader population of patients with unknown diabetes.


Subject(s)
Blood Glucose/metabolism , Diabetes Mellitus, Type 2/prevention & control , Internet , Patient Education as Topic/methods , Adult , Aged , Decision Making , Diabetes Mellitus, Type 2/blood , Early Diagnosis , Evidence-Based Medicine , Female , Health Knowledge, Attitudes, Practice , Humans , Intention , Male , Middle Aged , Patient Acceptance of Health Care , Prognosis , Surveys and Questionnaires
20.
Gesundheitswesen ; 73(12): 862-4, 2011 Dec.
Article in German | MEDLINE | ID: mdl-22193893

ABSTRACT

"Versorgungsforschung Deutschland" (Health Services Research Germany) is a database for health services research projects in Germany which is free, publicly accessible and still growing. The aim is to contribute to the transparency in this research field, to identify best practice models and to facilitate the exchange of research results. All researchers and all institutions which carry out health services research projects are requested to make projects directly known via this internet platform in order to promote the faster implementation of research results into practice.


Subject(s)
Data Mining/methods , Database Management Systems , Health Services Research/methods , Information Dissemination/methods , Internet , Germany
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