ABSTRACT
Central pontine and extra-pontine myelinolysis are a well known complication of hyponatremia. Other causes may be present. We report a case of head injury in a 13 year-old girl, who recovered well after surgery for extra-dural hematoma, but presented endocrinological disorders with hyperglycemia followed by a severe hyponatremia. Despite the correction of these metabolic disorders, the patient became comatose, and MRI, on T2 weighted image, showed hyperintense signals in the basal ganglia consistent with extra-pontine myelinolysis. The patient's state remained unchanged for six weeks. Since S. Konno and H. Wakui published cases of myelinolysis who dramatically improved after TRH treatment, the patient was given 0.6 mg i.v daily of TRH for six weeks. Improvement began within a few days, and continued until complete recovery.
Subject(s)
Brain/pathology , Craniocerebral Trauma/pathology , Demyelinating Diseases/drug therapy , Thyrotropin-Releasing Hormone/therapeutic use , Adolescent , Basal Ganglia/pathology , Cerebral Hemorrhage , Coma , Demyelinating Diseases/etiology , Demyelinating Diseases/pathology , Female , Humans , Magnetic Resonance Imaging , Pons/pathologyABSTRACT
The authors report a case of sino-venous thrombosis occurring in the course of trichinella infection in a 43 year-old man. MRI and angio-MRI showed a right rolandic haemorrhagic infarct and thrombosis of the superior sagittal and left lateral sinuses. Sino-venous thrombosis in such infection appears to be extremely rare. We found 4 reported cases which we compared to the present case. The findings of sino-venous thrombosis in relation with neurotrichinosis is examined.