Mismatch negativity between discriminating and undiscriminating participants on the front-back sound localization.

Sound localization in the front-back dimension is reported to be challenging, with individual differences. We investigated whether auditory discrimination processing in the brain differs based on front-back sound localization ability. This study conducted an auditory oddball task using speakers in front of and behind the participants. We used event-related brain potentials to examine the deviance detection process between groups that could and could not discriminate front-back sound localization. The results indicated that mismatch negativity (MMN) occurred during the deviance detection process, and P2 amplitude differed between standard and deviant locations in both groups. However, the latency of MMN was shorter in the group that could discriminate front-back sounds than in the group that could not. Additionally, N1 amplitude increased for deviant locations compared to standard ones only in the discriminating group. In conclusion, the sensory memories matching process based on traces of previously presented stimuli (MMN, P2) occurred regardless of discrimination ability. However, the response to changes in the physical properties of sounds (MMN latency, N1 amplitude) differed depending on the ability to discriminate front-back sounds. Our findings suggest that the brain may have different processing strategies for the two directions even without subjective recognition of the front-back direction of incoming sounds.

Perceptual anchoring: Children with dyslexia benefit less than controls from contextual repetitions in speech processing.

OBJECTIVES: Individuals with dyslexia perceive and utilize statistical features in the auditory input deficiently. The present study investigates whether affected children also benefit less from repeating context tones as perceptual anchors for subsequent speech processing. METHODS: In an event-related potential study, eleven-year-old children with dyslexia (n = 21) and without dyslexia (n = 20) heard syllable pairs, with the first syllable either receiving a constant pitch (anchor) or variable pitch (no-anchor), while second syllables were identical across conditions. RESULTS: Children with and without dyslexia showed smaller auditory P2 responses to constant-pitch versus variable-pitch first syllables, while only control children additionally showed smaller N1 and faster P1 responses. This suggests less automatic processing of anchor repetitions in dyslexia. For the second syllables, both groups showed faster P2 responses following anchor than no-anchor first syllables, but only controls additionally showed smaller P2 responses. CONCLUSIONS: Children with and without dyslexia show differences in anchor effects. While both groups seem to allocate less attention to speech stimuli after contextual repetitions, children with dyslexia display less facilitation in speech processing from acoustic anchors. SIGNIFICANCE: Altered anchoring in the linguistic domain may contribute to the difficulties of individuals with dyslexia in establishing long-term representations of speech.

On the Mathematical Relationship Between Contextual Probability and N400 Amplitude.

Accounts of human language comprehension propose different mathematical relationships between the contextual probability of a word and how difficult it is to process, including linear, logarithmic, and super-logarithmic ones. However, the empirical evidence favoring any of these over the others is mixed, appearing to vary depending on the index of processing difficulty used and the approach taken to calculate contextual probability. To help disentangle these results, we focus on the mathematical relationship between corpus-derived contextual probability and the N400, a neural index of processing difficulty. Specifically, we use 37 contemporary transformer language models to calculate the contextual probability of stimuli from 6 experimental studies of the N400, and test whether N400 amplitude is best predicted by a linear, logarithmic, super-logarithmic, or sub-logarithmic transformation of the probabilities calculated using these language models, as well as combinations of these transformed metrics. We replicate the finding that on some datasets, a combination of linearly and logarithmically-transformed probability can predict N400 amplitude better than either metric alone. In addition, we find that overall, the best single predictor of N400 amplitude is sub-logarithmically-transformed probability, which for almost all language models and datasets explains all the variance in N400 amplitude otherwise explained by the linear and logarithmic transformations. This is a novel finding that is not predicted by any current theoretical accounts, and thus one that we argue is likely to play an important role in increasing our understanding of how the statistical regularities of language impact language comprehension.

A registered report of a two-site study of variations of the flanker task: ERN experimental effects and data quality.

Error-related negativity is a widely used measure of error monitoring, and many projects are independently moving ERN recorded during a flanker task toward standardization, optimization, and eventual clinical application. However, each project uses a different version of the flanker task and tacitly assumes ERN is functionally equivalent across each version. The routine neglect of a rigorous test of this assumption undermines efforts to integrate ERN findings across tasks, optimize and standardize ERN assessment, and widely apply ERN in clinical trials. The purpose of this registered report was to determine whether ERN shows similar experimental effects (correct vs. error trials) and data quality (intraindividual variability) during three commonly used versions of a flanker task. ERN was recorded from 172 participants during three versions of a flanker task across two study sites. ERN scores showed numerical differences between tasks, raising questions about the comparability of ERN findings across studies and tasks. Although ERN scores from all three versions of the flanker task yielded high data quality and internal consistency, one version did outperform the other two in terms of the size of experimental effects and the data quality. Exploratory analyses of the error positivity (Pe) provided tentative support for the other two versions of the task over the paradigm that appeared optimal for ERN. The present study provides a roadmap for how to statistically compare psychometric characteristics of ERP scores across paradigms and gives preliminary recommendations for flanker tasks to use for ERN- and Pe-focused studies.

Investigating the neurocognitive background of speech perception with a fast multi-feature MMN paradigm.

The speech multi-feature MMN (Mismatch Negativity) offers a means to explore the neurocognitive background of the processing of multiple speech features in a short time, by capturing the time-locked electrophysiological activity of the brain known as event-related brain potentials (ERPs). Originating from Näätänen et al. (Clin Neurophysiol 115:140-144, 2004) pioneering work, this paradigm introduces several infrequent deviant stimuli alongside standard ones, each differing in various speech features. In this study, we aimed to refine the multi-feature MMN paradigm used previously to encompass both segmental and suprasegmental (prosodic) features of speech. In the experiment, a two-syllable long pseudoword was presented as a standard, and the deviant stimuli included alterations in consonants (deviation by place or place and mode of articulation), vowels (deviation by place or mode of articulation), and stress pattern in the first syllable of the pseudoword. Results indicated the emergence of MMN components across all segmental and prosodic contrasts, with the expected fronto-central amplitude distribution. Subsequent analyses revealed subtle differences in MMN responses to the deviants, suggesting varying sensitivity to phonetic contrasts. Furthermore, individual differences in MMN amplitudes were noted, partially attributable to participants' musical and language backgrounds. These findings underscore the utility of the multi-feature MMN paradigm for rapid and efficient investigation of the neurocognitive mechanisms underlying speech processing. Moreover, the paradigm demonstrated the potential to be used in further research to study the speech processing abilities in various populations.

A new method for tracking the preparatory activation of target templates for visual search with high temporal precision.

Efficiently selecting task-relevant objects during visual search depends on foreknowledge of their defining characteristics, which are represented within attentional templates. These templates bias attentional processing toward template-matching sensory signals and are assumed to become anticipatorily activated prior to search display onset. However, a direct neural signal for such preparatory template activation processes has so far remained elusive. Here, we introduce a new high-definition rapid serial probe presentation paradigm (RSPP-HD), which facilitates high temporal resolution tracking of target template activation processes in real time via monitoring of the N2pc component. In the RSPP-HD procedure, task-irrelevant probe displays are presented in rapid succession throughout the period between task-relevant search displays. The probe and search displays are homologously formed by lateralized "clouds" of colored dots, yielding probes that occur at task-relevant locations without confounding template-guided and salience-driven attentional shifts. Target color probes appearing at times when a corresponding target template is active should attract attention, thereby eliciting an N2pc. In a condition where new probe displays appeared every 50 ms, probe N2pcs were reliably elicited during the final 800 ms prior to search display onset, increasing in amplitude toward the end of this preparation period. Analogous temporal profiles were also observed with longer intervals between probes. These findings show that search template activation processes are transient and that their temporal profile can be reliably monitored at high-sampling frequencies with the RSPP-HD paradigm. This procedure offers a new route to approach various questions regarding the content and temporal dynamics of attentional control processes.

Machine Learning Classification of Event-Related Brain Potentials during a Visual Go/NoGo Task.

Machine learning (ML) methods are increasingly being applied to analyze biological signals. For example, ML methods have been successfully applied to the human electroencephalogram (EEG) to classify neural signals as pathological or non-pathological and to predict working memory performance in healthy and psychiatric patients. ML approaches can quickly process large volumes of data to reveal patterns that may be missed by humans. This study investigated the accuracy of ML methods at classifying the brain's electrical activity to cognitive events, i.e., event-related brain potentials (ERPs). ERPs are extracted from the ongoing EEG and represent electrical potentials in response to specific events. ERPs were evoked during a visual Go/NoGo task. The Go/NoGo task requires a button press on Go trials and response withholding on NoGo trials. NoGo trials elicit neural activity associated with inhibitory control processes. We compared the accuracy of six ML algorithms at classifying the ERPs associated with each trial type. The raw electrical signals were fed to all ML algorithms to build predictive models. The same raw data were then truncated in length and fitted to multiple dynamic state space models of order nx using a continuous-time subspace-based system identification algorithm. The 4nx numerator and denominator parameters of the transfer function of the state space model were then used as substitutes for the data. Dimensionality reduction simplifies classification, reduces noise, and may ultimately improve the predictive power of ML models. Our findings revealed that all ML methods correctly classified the electrical signal associated with each trial type with a high degree of accuracy, and accuracy remained high after parameterization was applied. We discuss the models and the usefulness of the parameterization.

Short- and long-term neuroplasticity interact during the perceptual learning of concurrent speech.

Plasticity from auditory experience shapes the brain's encoding and perception of sound. However, whether such long-term plasticity alters the trajectory of short-term plasticity during speech processing has yet to be investigated. Here, we explored the neural mechanisms and interplay between short- and long-term neuroplasticity for rapid auditory perceptual learning of concurrent speech sounds in young, normal-hearing musicians and nonmusicians. Participants learned to identify double-vowel mixtures during ~ 45 min training sessions recorded simultaneously with high-density electroencephalography (EEG). We analyzed frequency-following responses (FFRs) and event-related potentials (ERPs) to investigate neural correlates of learning at subcortical and cortical levels, respectively. Although both groups showed rapid perceptual learning, musicians showed faster behavioral decisions than nonmusicians overall. Learning-related changes were not apparent in brainstem FFRs. However, plasticity was highly evident in cortex, where ERPs revealed unique hemispheric asymmetries between groups suggestive of different neural strategies (musicians: right hemisphere bias; nonmusicians: left hemisphere). Source reconstruction and the early (150-200 ms) time course of these effects localized learning-induced cortical plasticity to auditory-sensory brain areas. Our findings reinforce the domain-general benefits of musicianship but reveal that successful speech sound learning is driven by a critical interplay between long- and short-term mechanisms of auditory plasticity, which first emerge at a cortical level.

Sound category habituation requires task-relevant attention.

Introduction: Processing the wealth of sensory information from the surrounding environment is a vital human function with the potential to develop learning, advance social interactions, and promote safety and well-being. Methods: To elucidate underlying processes governing these activities we measured neurophysiological responses to patterned stimulus sequences during a sound categorization task to evaluate attention effects on implicit learning, sound categorization, and speech perception. Using a unique experimental design, we uncoupled conceptual categorical effects from stimulus-specific effects by presenting categorical stimulus tokens that did not physically repeat. Results: We found effects of implicit learning, categorical habituation, and a speech perception bias when the sounds were attended, and the listeners performed a categorization task (task-relevant). In contrast, there was no evidence of a speech perception bias, implicit learning of the structured sound sequence, or repetition suppression to repeated within-category sounds (no categorical habituation) when participants passively listened to the sounds and watched a silent closed-captioned video (task-irrelevant). No indication of category perception was demonstrated in the scalp-recorded brain components when participants were watching a movie and had no task with the sounds. Discussion: These results demonstrate that attention is required to maintain category identification and expectations induced by a structured sequence when the conceptual information must be extracted from stimuli that are acoustically distinct. Taken together, these striking attention effects support the theoretical view that top-down control is required to initiate expectations for higher level cognitive processing.

Ignoring the alternatives: The N400 is sensitive to stimulus preactivation alone.

The N400 component of the event-related brain potential is a neural signal of processing difficulty. In the language domain, it is widely believed to be sensitive to the degree to which a given word or its semantic features have been preactivated in the brain based on the preceding context. However, it has also been shown that the brain often preactivates many words in parallel. It is currently unknown whether the N400 is also affected by the preactivations of alternative words other than the stimulus that is actually presented. This leaves a weak link in the derivation chain-how can we use the N400 to understand the mechanisms of preactivation if we do not know what it indexes? This study directly addresses this gap. We estimate the extent to which all words in a lexicon are preactivated in a given context using the predictions of contemporary large language models. We then directly compare two competing possibilities: that the amplitude of the N400 is sensitive only to the extent to which the stimulus is preactivated, and that it is also sensitive to the preactivation states of the alternatives. We find evidence of the former. This result allows for better grounded inferences about the mechanisms underlying the N400, lexical preactivation in the brain, and language processing more generally.

The Relationships Between Neural Activity and In-Game Hitting Performance in Baseball.

The current study examines the relationships between hitters' neural activity and their in-game hitting performance. Collegiate baseball players completed a computerized video task assessing whether thrown pitches were balls or strikes while their neural activity was recorded. In addition, each player's hitting statistics were collected for the following baseball season. Results showed that neural activity during the computerized task was associated with in-game hitting performance, even after accounting for other individual difference variables. These findings indicate that players' neural activity measured in a laboratory environment shows a translational relationship with in-game hitting performance over time. Neural activity provides a more objective analysis of players' ongoing self-regulatory processes during hitting and a better understanding of the cognitive processes associated with hitting performance. Self-regulatory cognitive control is adaptable and trainable, and this research advances the measurement of cognitive variables related with in-game hitting performance in baseball.

Strategic Processing of Gender Stereotypes in Sentence Comprehension: An ERP Study.

Gender stereotypes are often involved in language comprehension. This study investigated whether and to what extent their processing is under strategic control, by examining both proportion and order effects related to gender stereotypes for role nouns. We manipulated stereotypical gender consistencies, as in "Li's daughter/son was a nurse…", the relative proportions of gender-consistent and gender-inconsistent sentences (80%:20% and 50%:50% for high-proportion and equal-proportion sessions, respectively), and a between-participant factor of session order (high-proportion sessions preceding equal-proportion sessions and a reversed order for the high-equal and equal-high groups, respectively). Linear mixed-effect models revealed a larger N400 and a larger late negativity for stereotypically inconsistent compared to consistent sentences for the high-equal group only. These results indicate that even if sentence contexts have already determined the gender of target role characters, gender stereotypes for role nouns are still activated when the first half of the experiment facilitates their activation. The analyses of trial-by-trial dynamics showed that the N400 effects gradually decreased throughout equal-proportion sessions for the equal-high group. Our findings suggest that the processing of gender stereotypes can be under strategic control. In addition, readers may develop other strategies based on sentence contexts, when the processing strategy based on cue validity is not available.

Discourse Context Immediately Overrides Gender Stereotypes during Discourse Reading: Evidence from ERPs.

This study investigated how local gender stereotype information interacts with discourse context during Chinese discourse reading. Event-related potentials were recorded while participants read two-sentence discourses, in which the first sentence provided the discourse context that either introduced a gender stereotype-countering attitude towards roles, such as "One should strive for the target job, and getting a job should not be restricted by gender"., or was neutral. The second sentence contained the critical clause in which the stereotypical gender of the object noun (a role name) was either consistent or inconsistent with the gender specified by the head noun (a kinship term) of the subject noun phrase, as in "Li's [daughter/son] became a nurse…". The object nouns elicited a larger N400 and a larger late negativity (LN) for the inconsistent compared to the consistent conditions in the neutral contexts. Crucially, when the discourse context offered information countering gender stereotypes, both the N400 and LN effects were reversed, with the negativities being smaller for the inconsistent compared to the consistent conditions. The reversal of the N400 effects suggests that discourse contexts can immediately override the processing of gender stereotypes, and thus readers compute discourse context and local pragmatic information simultaneously during discourse reading.

On the spread of spatial attention in touch: Evidence from event-related brain potentials.

To investigate the distribution of tactile spatial attention near the current attentional focus, participants were cued to attend to one of four body locations (hand or shoulder on the left or right side) to respond to infrequent tactile targets. In this Narrow attention task, effects of spatial attention on the ERPs elicited by tactile stimuli delivered to the hands were compared as a function of the distance from the attentional focus (Focus on the hand vs. Focus on the shoulder). When participants focused on the hand, attentional modulations of the sensory-specific P100 and N140 components were followed by the longer latency Nd component. Notably, when participants focused on the shoulder, they were unable to restrict their attentional resources to the cued location, as revealed by the presence of reliable attentional modulations at the hands. This effect of attention outside the attentional focus was delayed and reduced compared to that observed within the attentional focus, revealing the presence of an attentional gradient. In addition, to investigate whether the size of the attentional focus modulated the effects of tactile spatial attention on somatosensory processing, participants also completed the Broad attention task, in which they were cued to attend to two locations (both the hand and the shoulder) on the left or right side. Attentional modulations at the hands emerged later and were reduced in the Broad compared to the Narrow attention task, suggesting reduced attentional resources for a wider attentional focus.

Neurocognitive effects of binge drinking on verbal episodic memory. An ERP study in university students.

Background: Verbal memory may be affected by engagement in alcohol binge drinking during youth, according to the findings of neuropsychological studies. However, little is known about the dynamics of the neural activity underlying this cognitive process in young, heavy drinkers. Aims: To investigate brain event-related potentials associated with cued recall from episodic memory in binge drinkers and controls. Methods: Seventy first-year university students were classified as binge drinkers (32: 17 female) or controls (38: 18 female). The participants completed a verbal paired associates learning task during electroencephalogram (EEG) recording. ERPs elicited by old and new word pairs were extracted from the cued-recall phase of the task by using Principal Component Analysis. Subjects also performed a standardized neuropsychological verbal learning test. Results: Two of the three event-related potentials components indicating old/new memory effects provided evidence for anomalies associated with binge drinking. The old/new effects were absent in the binge drinkers in the two subsequent posterior components, identified with the late parietal component and the late posterior negativity The late frontal component revealed similar old/new effects in both groups. Binge drinkers showed similar behavioural performance to controls in the verbal paired associates task, but performed poorly in the more demanding short-term cued-recall trial of a neuropsychological standardized test. Conclusion: Event-related potentials elicited during a verbal cued-recall task revealed differences in brain functioning between young binge drinkers and controls that may underlie emergent deficits in episodic memory linked to alcohol abuse. The brain activity of binge drinkers suggests alterations in the hippocampal - posterior parietal cortex circuitry subserving recognition and recollection of the cue context and generation of the solution, in relation to verbal information shallowly memorised.

Effects of iron supplementation on neural indices of habituation in Bangladeshi children.

BACKGROUND: Iron deficiency and anemia have been associated with poor cognition in children, yet the effects of iron supplementation on neurocognition remain unclear. OBJECTIVE: We aimed to examine the effects of supplementation with iron on neural indices of habituation using auditory event-related brain potentials (ERPs). METHODS: This substudy was nested within a 3-arm, double-blind, double-dummy, individual randomized trial in Bangladesh, in which 3300 8-mo-old children were randomly selected to receive 3 mo of daily iron syrup (12.5 mg iron), multiple micronutrient powders (MNPs) (including 12.5 mg iron), or placebo. Children were assessed after 3 mo of intervention (mo 3) and 9 mo thereafter (mo 12). The neurocognitive substudy comprised a randomly selected subset of children from the main trial. Brain activity elicited during an auditory roving oddball task was recorded using electroencephalography to provide an index of habituation. The differential response to a novel (deviant) compared with a repeated (standard) sound was examined. The primary outcome was the amplitude of the mismatch response (deviant minusstandard tone waveforms) at mo 3. Secondary outcomes included the deviant and standard tone-evoked amplitudes, N2 amplitude differences, and differences in mean amplitudes evoked by deviant tones presented in the second compared with first half of the oddball sequence at mo 3 and 12. RESULTS: Data were analyzed from 329 children at month 3 and 363 at mo 12. Analyses indicated no treatment effects of iron interventions compared with placebo on the amplitude of the mismatch response (iron syrup compared with placebo: mean difference (MD) = 0.07µV [95% CI: -1.22, 1.37]; MNPs compared with placebo: MD = 0.58µV [95% CI: -0.74, 1.90]) nor any secondary ERP outcomes at mo 3 or 12, despite improvements in hemoglobin and ferritin concentrations from iron syrup and MNPs in this nested substudy. CONCLUSION: In Bangladeshi children with >40% anemia prevalence, iron or MNP interventions alone are insufficient to improve neural indices of habituation. This trial was registered at the Australian New Zealand Clinical Trials Registry as ACTRN12617000660381.

Altered Feedback-Related Negativity in Mild Cognitive Impairment.

INTRODUCTION: Feedback-related negativity (FRN) is electrical brain activity related to the function of monitoring behavior and its outcome. FRN is generated by negative feedback input, such as punishment or monetary loss, and its potential is distributed maximally over the frontal-central part of the skull. Our previous study demonstrated that FRN latency was delayed and that the amplitude was increased in patients with mild Alzheimer's disease (AD). As mild cognitive impairment (MCI) is considered to be a prodromal stage of AD, we speculated that FRN would also be altered in MCI, as in AD. The aim of this study is to examine whether MCI patients showed changes in FRN during a gambling task. METHODS: Thirteen MCI patients and thirteen age-matched healthy elderly individuals participated in a simple gambling task and underwent neuro-psychological assessments. The participants were asked to choose one out of two options and randomly received positive or negative feedback to their response. An EEG was recorded during the task, and FRN was obtained by subtracting the positive feedback-related activity from the negative feedback-related activity. RESULTS: The reaction time to probe stimuli was comparable in the two groups. The group comparisons revealed that the FRN amplitude was significantly larger for the MCI group than for the healthy elderly (F(1,24) = 6.4, ηp2 = 0.22, p = 0.019), but there was no group difference in the FRN latency. The FRN amplitude at the frontocentral electrode positively correlated with the mini-mental state examination score (Spearman's rhopartial = 0.41, p = 0.043). The finding of increased FRN amplitude in MCI was consistent with the previous finding in AD. CONCLUSION: Our findings indicate that monitoring dysfunction might also be involved in the prodromal stage of dementia.

Neural empathic response to disability: An ERP study of prejudice.

While social neuroscience has already provided evidence for a deficit of affective empathy in racial prejudice, little is known about other less visible social categories when considered as an outgroup. We studied the process of empathy through event-related brain potentials (ERPs). We focused on the group "people with disabilities" as they are the target of a large amount of prejudice. Twenty-six participants performed a pain decision task. The mean amplitudes of N1, P2, N2-N3 and P3 components were recorded. Our results are consistent with previous work on prejudice, showing that the pain detection is modulated by group membership (with disabilities vs. without disabilities) on N2-N3, suggesting a better neural decoding of pain vs. non-pain in the without-disability condition. Critically, no effect of early sensory components (N1, P2) was found, and P3 was not moderated by disability. These findings indicate a different time course of empathic responses depending on the condition, suggesting that people with disabilities trigger specific empathic responses. Our results contribute to disentangling perceptual processes from affective empathy reactions.

Event-related brain potential correlates of the other-race effect: A review.

People are better at remembering own-race relative to other-race faces. Here, we review event-related brain potential (ERP) correlates of this so-called other-'race' effect (ORE) by discussing three critical aspects that characterize the neural signature of this phenomenon. First, difficulties with other-race faces initially emerge during perceptual processing, which is indexed by an increased N170. Second, as evidenced by 'difference due to subsequent memory' effects, more effortful processing of other-race faces is needed for successful encoding into long-term memory. Third, ERP old/new effects reveal that a stronger engagement of processing resources is also required for successful retrieval of other-race faces from memory. The ERP evidence available to date thus suggests widespread ethnicity-related modulations during both perceptual and mnemonic processing stages. We further discuss how findings from the ORE compared with potentially related memory biases (e.g. other-gender or other-age effects) and how ERP findings inform the ongoing debate regarding the mechanisms underlying the ORE. Finally, we outline open questions and potential future directions with an emphasis on using multiple, ecologically more valid 'ambient' images for each face to assess the ORE in paradigms that capture identity rather than image recognition.

Children with amblyaudia show less flexibility in auditory cortical entrainment to periodic non-speech sounds.

OBJECTIVE: We investigated auditory temporal processing in children with amblyaudia (AMB), a subtype of auditory processing disorder (APD), via cortical neural entrainment. DESIGN AND STUDY SAMPLES: Evoked responses were recorded to click-trains at slow vs. fast (8.5 vs. 14.9/s) rates in n = 14 children with AMB and n = 11 age-matched controls. Source and time-frequency analyses (TFA) decomposed EEGs into oscillations (reflecting neural entrainment) stemming from bilateral auditory cortex. RESULTS: Phase-locking strength in AMB depended critically on the speed of auditory stimuli. In contrast to age-matched peers, AMB responses were largely insensitive to rate manipulations. This rate resistance occurred regardless of the ear of presentation and in both cortical hemispheres. CONCLUSIONS: Children with AMB show less rate-related changes in auditory cortical entrainment. In addition to reduced capacity to integrate information between the ears, we identify more rigid tagging of external auditory stimuli. Our neurophysiological findings may account for domain-general temporal processing deficits commonly observed in AMB and related APDs behaviourally. More broadly, our findings may inform communication strategies and future rehabilitation programmes; increasing the rate of stimuli above a normal (slow) speech rate is likely to make stimulus processing more challenging for individuals with AMB/APD.