A guideline for the appropriate recognition of shared resource laboratories in publication.

The issue of what level of contribution warrants authorship, determining a fair order of authors and when and whom to acknowledge in publications is often a cause of debate, and in some instances, has also been a focus of conflict at certain institutions. Shared resource laboratories (SRLs) play a fundamental role in supporting publications, and SRL staff scientists can contribute to numerous areas such as experimental design, sample preparation, data acquisition, data analysis and manuscript drafting and review. However, SRL staff scientists are often unfairly omitted from the author list. To avoid SRLs and SRL staff scientist contributions going unnoticed, the authors have formulated a set of guidelines to aid in the conceptualization and recognition of the technical and intellectual contributions of SRLs. As a better understanding of the role SRL staff scientists play in the achievement of the scientific lead's experimental aims will foster a positive feedback loop, where acknowledgements can lead to more support and funding for SRLs and more engaged SRL staff capable of supporting discoveries and technological innovations that underpin major advancements in the field of life sciences.

Predictors of psychological distress amongst nursing students: A multicenter cross-sectional study.

Undergraduate nursing students show high-stress levels. In students, stress has been linked to adverse physical and psychological health outcomes and academic and clinical demands. To date, there are few studies dealing with psychological predictors of stress amongst nursing students. This study aimed to assess psychological distress in a sample of Italian nursing students and to explore its relationship with sociodemographic and psychological factors, specifically dispositional mindfulness, emotional regulation difficulties, and empathy. A multicenter cross-sectional survey design was employed. Participants were recruited from five teaching hospitals associated with a public university in northern Italy. A sample of 622 undergraduate nursing students was recruited. Participants were recruited on campus and completed a paper-and-pencil survey. More than 70% of nursing students reported meaningful levels of psychological distress. Students with higher dispositional mindfulness scores had lower psychological distress, whereas emotional regulation difficulties and empathic personal distress were positively associated with perceived stress. No gender differences were found in stress levels, but senior students showed lower psychological distress than more junior students. Interventions aimed at increasing mindfulness facets and improving emotional regulation strategies may help to reduce perceived psychological stress in nursing students.

Antimicrobial effects of various platelet rich concentrates-vibes from in-vitro studies-a systematic review.

AIM: The aim of the current review was to outline the existing information related to antimicrobial properties of various platelet concentrates, as experimented in various in-vitro studies. BACKGROUND: One of the most interesting recent landmarks in the field of biological therapy has been the discovery that platelets, in addition to being capable of releasing hundreds of proteins and growth factors, can also release immunomodulatory agents with antimicrobial activity. Several international research groups have reported antimicrobial activities in both human platelets and other types of platelet rich plasma preparations. REVIEW RESULT: This review was carried-out pursuing a systematic approach. An electronic search was conducted on MEDLINE and GOOGLE SCHOLAR databases using suitable search terminologies. It included preclinical studies which assessed the antimicrobial activity of Autologous Platelet Concentrates(APC).Ten in-vitro studies and one animal study, which investigated APC effects on various microorganisms, were included. Almost in all the included in-vitro studies, it was found that complete breakdown of microbial load could not be achieved by any of the APC preparations but there occurred a reduction in the growth of microorganisms. Thus APCs displayed a bacteriostatic rather than bacteriocidal activity.The only animal study included in this review which had both in-vitro and in-vivo evaluation, also showed reduction of infection caused by different microorganisms. CONCLUSION: Although the precise mechanism of synergy with microbial pathogens needs further validation, platelet concentrates proved to have antimicrobial properties.

Dental caries and the associated factors influencing it in tribal, suburban and urban school children of Tamil Nadu, India: a cross sectional study.

BACKGROUND: The study was planned to assess the prevalence of dental caries among tribal, suburban and urban children of Tiruchengode and Erode of Tamil Nadu state, India. The objective of the study was to assess the association of dental caries with family background, dental service availability, transportation and knowledge on preventive dental measures among these three groups. DESIGN AND METHODS: Cross-sectional study. A total of 1028 school children in the age range of 9-12 years from various government schools located in Palamalai and Kolli Hills (tribal), Tiruchengode (suburban) and Erode (urban), Tamil Nadu, were included in the study. Decayed, filled, and missing teeth (DMFT), decayed and filled teeth (dft) and Significant Caries Index were recorded. A specially prepared questionnaire was used to record all the data regarding oral hygiene practices, socioeconomic background, dental treatment availability, parent's education level were used for the study. ANOVA t-test and post hoc test were used for comparing quantitative variables between the 3 subgroups. RESULTS: The tribal school children had 89.3% caries prevalence, where as it was 77% in suburban and 55% in urban school children. The mean DMFT score among tribal, suburban and urban school children were statistically significant different (P=0.001) between the three groups. There was a highly significant difference (P=0.001) in the mean DMFT score based on brushing frequency. There was a statistically significant difference (P=0.018) in the mean DMFT scores in the urban group based on the mothers education status. There were no statistically significant differences in the mean DMFT scores based on the presence or absence of television in their house and the parents' income. CONCLUSIONS: Oral hygiene practices, dietary habits and access to dental care services played an important role in prevalence of dental caries. It was observed that the socioeconomic status, parents' educational status and mass media influenced the oral health of these children but without a significant contribution. Significance for public healthIt was observed from the present study that the socioeconomic status, parents' educational status, media and family structure influence the oral health of children in under-privileged communities. Oral hygiene practices, dietary habits and access to dental care services also play an important role in the prevalence of dental caries among children. Children of government schools in Tamil Nadu, India, don't get adequate information on oral health, related diseases and methods of prevention. Oral health education and health promotion should be mandatory for all school children.

Looking for the impact of peer review: does count of funding acknowledgements really predict research impact?

A small number of studies have sought to establish that research papers with more funding acknowledgements achieve higher impact and have claimed that such a link exists because research supported by more funding bodies undergoes more peer review. In this paper, a test of this link is made using recently available data from the Web of Science, a source of bibliographic data that now includes funding acknowledgements. The analysis uses 3,596 papers from a single year, 2009, and a single journal, the Journal of Biological Chemistry. Analysis of this data using OLS regression and two ranks tests reveals the link between count of funding acknowledgements and high impact papers to be statistically significant, but weak. It is concluded that count of funding acknowledgements should not be considered a reliable indicator of research impact at this level. Relatedly, indicators based on assumptions that may hold true at one level of analysis may not be appropriate at other levels.