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1.
West Afr J Med ; 41(7): 831-835, 2024 Jul 30.
Article in English | MEDLINE | ID: mdl-39357067

ABSTRACT

A 30-year-old G4P1+2(1 alive) woman with a history of cervical incompetence initially presented at a gestational age (GA) of 10 weeks and 6 days with lower abdominal pain and was managed conservatively as a case of threatened miscarriage. She re-presented two weeks later and was admitted on account of lower abdominal pain and spotting per vagina of 4hrs duration. An obstetric ultrasound revealed an intrauterine pregnancy invading the posterior myometrium with thinning of the uterine wall and hemoperitoneum. She subsequently had an exploratory laparotomy, evacuation of the hemoperitoneum, separation of the fetus from the myometrium, and repair with no. 2 vicryl suture. The patient recovered satisfactorily and had two units of whole blood transfused. She was managed with analgesics, hematinics and broad-spectrum antibiotics. She was discharged on the 4th post-operative day to be followed up at the gynaecological clinic.


CONTEXTE: Une femme de 30 ans, G4P1+2(1 vivant) avec des antécédents d'incompétence cervicale, s'est initialement présentée à un âge gestationnel (AG) de 10 semaines et 6 jours avec des douleurs abdominales basses et a été prise en charge de manière conservatrice pour une menace de fausse couche. Elle s'est à nouveau présentée deux semaines plus tard et a été admise en raison de douleurs abdominales basses et de saignements vaginaux depuis 4 heures. Une échographie obstétricale a révélé une grossesse intra-utérine envahissant le myomètre postérieur avec amincissement de la paroi utérine et hémopéritoine. Elle a ensuite subi une laparotomie exploratrice, une évacuation de l'hémopéritoine, une séparation dufœtus du myomètre, et une réparation avec un fil de suture vicryl n° 2. La patiente a récupéré de manière satisfaisante et a reçu deux unités de sang total en transfusion. Elle a été prise en charge avec des analgésiques, des hématiniques et des antibiotiques à large spectre. Elle a été autorisée à sortir le 4ème jour post-opératoire avec un suivi prévu à la clinique gynécologique. MOTS-CLÉS: Grossesse intramurale, Dilemme, Pratique à ressources limitées.


Subject(s)
Hemoperitoneum , Humans , Female , Pregnancy , Adult , Hemoperitoneum/diagnosis , Hemoperitoneum/etiology , Pregnancy, Ectopic/diagnosis , Abdominal Pain/etiology , Laparotomy/methods , Abortion, Threatened/diagnosis , Ultrasonography, Prenatal/methods
2.
JNMA J Nepal Med Assoc ; 62(274): 404-406, 2024 May 31.
Article in English | MEDLINE | ID: mdl-39356859

ABSTRACT

ABSTRACT: Developmental anomalies of genital tract result from defective fusion and absorption of various parts of Mullerian ducts in fetal life. Rudimentary horn pregnancy (RHP) is a rare occurrence of one in 76,000 and one in 160,000. We present a case of a 24-year-old primigravida with ruptured RHP initially managed in the line of an intrauterine pregnancy with severe anemia. Hemodynamic instability made us suspect ruptured RHP and lifesaving laparotomy was performed for the same. A 1.5-liter hemoperitoneum was encountered with a right RHP. Multiple adhesions were present with necrotic tissue adherent and clumped together as tubo-ovarian mass. Resection of rudimentary horn was performed. We report this case to emphasize the need to consider rare uterine anomalies as a possibility in patients presenting with acute abdomen in early pregnancy. So, Obstetricians can consider these rare entities in differential diagnosis and management.


Subject(s)
Shock , Humans , Female , Pregnancy , Shock/etiology , Shock/diagnosis , Young Adult , Uterus/abnormalities , Hemoperitoneum/etiology , Hemoperitoneum/diagnosis , Hemoperitoneum/surgery , Uterine Rupture/diagnosis , Uterine Rupture/etiology , Uterine Rupture/surgery , Abdomen, Acute/etiology , Abdomen, Acute/diagnosis , Laparotomy/methods
3.
Medicine (Baltimore) ; 103(38): e39713, 2024 Sep 20.
Article in English | MEDLINE | ID: mdl-39312322

ABSTRACT

RATIONALE: Ruptured tubal pregnancies occurring in the second trimester are rare; yet, they pose a critical risk of life-threatening hemorrhage. This study aims to highlight the importance of timely surgical intervention in such cases to prevent fatal outcomes. The case underscores the diagnostic and therapeutic challenges that arise when distinguishing between tubal and abdominal pregnancies, particularly in the presence of hemoperitoneum, which can obscure imaging results. PATIENT CONCERNS: We present a case involving the spontaneous rupture of a tubal pregnancy at 15 weeks and 3 days of gestation. The patient exhibited elevated beta-human chorionic gonadotropin levels. Initial transabdominal ultrasound suggested an abdominal pregnancy, and computed tomography scans supported these findings. DIAGNOSES AND INTERVENTIONS: Urgent midline laparotomy revealed the condition to be a tubal pregnancy, contrary to initial imaging. The surgical procedure included the removal of the gestational sac and the affected fallopian tube, followed by abdominal closure. Hemoperitoneum was noted to compromise the accuracy of imaging modalities, complicating the preoperative diagnosis. OUTCOMES: Histopathological examination confirmed the diagnosis of tubal pregnancy. The patient had an uneventful recovery and was discharged 7 days post-surgery with stable hemoglobin levels. LESSONS: This case underscores the importance of considering the differential diagnosis of abdominal versus tubal pregnancy in the presence of hemoperitoneum, due to their differing clinical management needs. It offers insights that may guide clinicians in the timely diagnosis and treatment of advanced tubal pregnancies, where prompt surgical intervention is critical.


Subject(s)
Hemoperitoneum , Pregnancy, Tubal , Humans , Female , Pregnancy , Pregnancy, Tubal/surgery , Pregnancy, Tubal/diagnosis , Pregnancy, Tubal/diagnostic imaging , Adult , Hemoperitoneum/etiology , Hemoperitoneum/surgery , Hemoperitoneum/diagnosis , Rupture, Spontaneous/surgery , Diagnosis, Differential , Fetal Membranes, Premature Rupture , Pregnancy, Abdominal/surgery , Pregnancy, Abdominal/diagnosis
4.
BMJ Case Rep ; 17(9)2024 Sep 05.
Article in English | MEDLINE | ID: mdl-39242126

ABSTRACT

Spontaneous haemoperitoneum is described as a collection of blood in the peritoneal cavity due to non-traumatic aetiology. Common causes in the literature include splenic, hepatic and gynaecological pathology. Patients with spontaneous haemoperitoneum usually present with non-specific dull aching abdominal pain. Spontaneous haemoperitoneum can only be radiologically diagnosed and, if not treated in time, is life threatening. Rupture of a gastrointestinal stromal tumour (GIST) presenting as a spontaneous haemoperitoneum is a rare event. Gastric GIST presents as ambiguous abdominal pain, complications of which include melena, obstruction and rupture. This is a report of a male patient in his early 60s who presented with acute abdominal pain. A contrast-enhanced CT of the abdomen showed haemoperitoneum with an unknown source of origin. Diagnostic laparoscopy showed a bleeding exophytic mass arising from the stomach, which was resected. Thus, early diagnosis with proper imaging and prompt treatment has a favourable outcome.


Subject(s)
Gastrointestinal Stromal Tumors , Hemoperitoneum , Stomach Neoplasms , Humans , Hemoperitoneum/etiology , Hemoperitoneum/surgery , Gastrointestinal Stromal Tumors/complications , Gastrointestinal Stromal Tumors/diagnosis , Male , Middle Aged , Stomach Neoplasms/complications , Stomach Neoplasms/diagnosis , Tomography, X-Ray Computed , Gastrointestinal Hemorrhage/etiology , Abdominal Pain/etiology
5.
Taiwan J Obstet Gynecol ; 63(5): 768-770, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39266163

ABSTRACT

OBJECTIVE: Our aim is to demonstrate a rare cause of hemoperitoneum without vaginal bleeding resulting from the rupture of a uterine artery pseudoaneurysm after uncomplicated vaginal delivery. CASE REPORT: A 39-year-old woman who had experienced a normal vaginal delivery 8 days previously to being seen in our hospital, was presented to the emergency room with hypovolemic shock. Computed tomography angiography (CTA) showed massive internal bleeding and a ruptured pseudoaneurysm arising from the left uterine artery. The patient was successfully treated through transcatheter arterial embolization (TAE). CONCLUSION: A pseudoaneurysm is a rare disease which can occur during an uncomplicated vaginal delivery. The clinical presentation can vary from asymptomatic, vaginal bleeding or hemoperitoneum. The diagnosis can be made by using Doppler sonography, CTA or Magnetic Resonance Imaging. The use of TAE is now the most common treatment option and possesses a high success rate.


Subject(s)
Aneurysm, False , Hemoperitoneum , Uterine Artery , Humans , Female , Hemoperitoneum/etiology , Hemoperitoneum/therapy , Adult , Aneurysm, False/therapy , Aneurysm, False/etiology , Aneurysm, False/diagnostic imaging , Uterine Artery/diagnostic imaging , Delivery, Obstetric/adverse effects , Computed Tomography Angiography , Aneurysm, Ruptured/therapy , Aneurysm, Ruptured/complications , Aneurysm, Ruptured/diagnostic imaging , Pregnancy , Uterine Artery Embolization , Embolization, Therapeutic/methods , Postpartum Hemorrhage/etiology , Postpartum Hemorrhage/therapy
6.
J Int Med Res ; 52(7): 3000605241261893, 2024 Jul.
Article in English | MEDLINE | ID: mdl-39053448

ABSTRACT

Abdominal pregnancies are a rare form of ectopic pregnancy with omentum pregnancies being even rarer. Ectopic pregnancy should be diagnosed and terminated early to prevent the risk of harm to the mother. This case report describes a rare case of omentum pregnancy with severe hemoperitoneum. The patient had not visited a doctor until she failed to menstruate for 3 months, by which point she had developed severe hypogastralgia. The patient was diagnosed with a ruptured ectopic pregnancy after ultrasonography. The omentum pregnancy was complicated by severe hemoperitoneum, which was confirmed by emergency laparotomy. The patient was treated successfully with fetal extraction and partial omentectomy. Ultrasound examination in early pregnancy is essential to detect and treat ectopic pregnancies as early as possible, as surgery is usually required for abdominal pregnancies. Prompt treatment of ectopic pregnancies is critical, as an omentum pregnancy is dangerous and may result in severe intraperitoneal bleeding.


Subject(s)
Hemoperitoneum , Omentum , Humans , Female , Hemoperitoneum/surgery , Hemoperitoneum/etiology , Hemoperitoneum/diagnosis , Pregnancy , Omentum/surgery , Omentum/pathology , Adult , Pregnancy, Abdominal/surgery , Pregnancy, Abdominal/diagnosis , Ultrasonography , Pregnancy, Ectopic/surgery , Pregnancy, Ectopic/diagnosis , Pregnancy, Ectopic/diagnostic imaging
7.
Rev Gastroenterol Peru ; 44(2): 140-144, 2024.
Article in Spanish | MEDLINE | ID: mdl-39019807

ABSTRACT

Malignant peripheral nerve sheath tumors are frequently associated with neurofibromatosis type 1. They are usually located in the extremities or in the axial area. Its visceral location is very rare and its hepatic origin is infrequent. They tend to be aggressive with a poor response to chemotherapy and radiotherapy, so surgical management is the best treatment option. We present the case of a young man with neurofibromatosis type 1, who presented with hemoperitoneum as a complication of a malignant tumor of the peripheral nerve sheath located in the liver.


Subject(s)
Hemoperitoneum , Liver Neoplasms , Nerve Sheath Neoplasms , Humans , Male , Hemoperitoneum/etiology , Nerve Sheath Neoplasms/complications , Nerve Sheath Neoplasms/diagnosis , Liver Neoplasms/complications , Liver Neoplasms/secondary , Adult , Neurofibromatosis 1/complications
8.
BMJ Case Rep ; 17(6)2024 Jun 27.
Article in English | MEDLINE | ID: mdl-38937262

ABSTRACT

A man in his 70s presented with a sudden onset stabbing back pain radiating to the chest and pre-syncopal symptoms. He underwent urgent investigations, including a CT angiogram aorta which did not reveal any abnormalities within the thorax, abdomen or pelvis and no cause of symptoms was identified. After being discharged, he re-presented 2 days later with syncopal episodes, abdominal pain and a significant drop in haemoglobin levels. This time, a CT mesenteric angiogram showed two hepatic artery pseudoaneurysms and a large haemoperitoneum. Following a hepatic artery embolisation, a workup showed that the likely cause of the pseudoaneurysms was a rare first presentation of polyarteritis nodosa. This case highlights the importance of considering the possibility of an aneurysmal rupture, especially when common causes of an acute abdomen have been excluded, and not relying on previous negative investigations to exclude pathology, as the outcomes can be detrimental.


Subject(s)
Aneurysm, False , Hepatic Artery , Polyarteritis Nodosa , Humans , Polyarteritis Nodosa/complications , Aneurysm, False/diagnostic imaging , Aneurysm, False/etiology , Aneurysm, False/complications , Male , Hepatic Artery/diagnostic imaging , Aged , Embolization, Therapeutic , Aneurysm, Ruptured/diagnostic imaging , Aneurysm, Ruptured/complications , Computed Tomography Angiography , Rupture, Spontaneous , Hemoperitoneum/etiology , Abdominal Pain/etiology
10.
Int J Gynaecol Obstet ; 167(1): 395-402, 2024 Oct.
Article in English | MEDLINE | ID: mdl-38721644

ABSTRACT

INTRODUCTION: Contrast-enhanced computed tomography (CECT) is an emergent diagnostic imaging modality to identify the bleeding site and survey the abdominal cavity. The diagnostic utility of CECT for ectopic pregnancy (EP) has not been well-investigated. The objective of this study was to evaluate the characteristics of CECT findings in patients with EP and extract specific findings that could contribute to the identification of implantation sites. METHOD: We conducted a retrospective study, reviewing suspected EP cases between April 2015 and March 2018 in our hospital. Clinical symptoms, blood test results, transvaginal sonography findings, and surgical and pathologic findings from the medical records were assessed. CECT images were evaluated by a certified radiologist and gynecologist retrospectively in consensus. The following were selected as positive findings for specific determination of the ectopic implantation site: the ectopic gestational sac, lateralization of the hemoperitoneum around the adnexa on either side, and extravascular leakage of the contrast agent outside the uterine cavity. RESULTS: CECT was performed in 41 women with an EP. The ectopic implantation site was detectable on CECT in 90.2% (37/41), whereas it was noted in 70.0% (32/41) on transvaginal ultrasonography (TVS). Of nine patients with an EP with an undetectable implantation site on TVS, six were positive for the specific determination of the ectopic implantation site on CECT. CONCLUSION: CECT has the potential to predict ectopic implantation sites with high-level sensitivity. As CECT is an urgent diagnostic imaging tool to be used in an emergent setting, it may be a good option for EP diagnosis when the availability of magnetic resonance imaging is limited.


Subject(s)
Contrast Media , Pregnancy, Ectopic , Tomography, X-Ray Computed , Humans , Female , Pregnancy , Retrospective Studies , Pregnancy, Ectopic/diagnostic imaging , Adult , Tomography, X-Ray Computed/methods , Ultrasonography/methods , Hemoperitoneum/diagnostic imaging , Young Adult
12.
Fertil Steril ; 121(2): 355-357, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38742286

ABSTRACT

OBJECTIVE: To report an uncommon case of primary OP treated laparoscopically. Ectopic pregnancy (EP) is the leading cause of maternal mortality during the first trimester and the incidence increases with assisted reproductive techniques, occurring in approximately 1.5%-2.1% of patients undergoing in vitro fertilization.1 Omental pregnancy (OP) is an extremely rare form of EP accounting for less than 1% of all EPs. OP can be classified as primary or secondary on the basis of Studdiford's criteria2. The preoperative diagnosis of OP is complex and usually occur in acute circumstances during a throughout intraoperative evaluation of the abdomen.3-5 A delayed diagnosis poses a serious threat to the survival of the patient; therefore, it is important to remark that EP can exist in unusual locations and prompt surgical intervention may be necessary. DESIGN: A step-by-step narrated video of a rare clinical case and description of the surgical procedure. SETTING: Tertiary Level Academic Hospital "IRCCS Azienda Ospedaliero - Universitaria di Bologna" Bologna, Italy. PATIENT: A 36-year-old woman was referred to our emergency room because of acute abdominal pain and nausea for 2 hours with no signs of hemodynamic instability. The patient also complained that poor vaginal bleeding appeared during the last 24 hours. The patient has undergone a cycle of in vitro fertilization with an elective single frozen embryo transfer of a blastocyst on day 5, 2 months before. She had no relevant clinical or surgical history. Diffuse abdominal tenderness and a painful uterus at mobilization were appreciated at clinical examination. A massive hemoperitoneum was diagnosed using transvaginal-transabdominal ultrasound, and no uterine or adnexal lesions were identified. The ß-human chronic gonadotropin level was 43.861 mIU/mL, and the hemoglobin value was 10.5 g/dL. INTERVENTIONS: On suspicion of a ruptured EP, after detailed counseling and the acquisition of informed consent, a laparoscopic exploration was planned. First, the hemoperitoneum was evacuated to allow visualization of the abdominal cavity. At pelvic inspection, no EP was found. Throughout the exploration of the abdominal cavity, a 4-cm bluish cystic mass of friable consistency was detected infiltrating the omentum and the mesentery. According to Studdiford's criteria, the diagnosis of a primary OP was established. A careful and complete excision of the ectopic implant was performed with an ultrasonic system and required a considerable hemostatic effort using bipolar energy, endoscopic clips, and mechanical compression. The postoperative course was uneventful. The ß-human chronic gonadotropin levels gradually decreased to negative values within 29 days after surgery. MAIN OUTCOME MEASURE(S): Omental ectopic pregnancy can be successfully managed with a laparoscopic approach even in an emergency setting. CONCLUSION: Omental pregnancy can easily be overlooked, even by skilled surgeons, during laparoscopic exploration. It is mandatory that all peritoneal surfaces and the omentum be carefully inspected during surgery in patients without other signs of pelvic EP.We confirm that the patient included in this video gave consent for publication of the video and posting of the video online, including on social media, the journal website, scientific literature websites, and other applicable sites.


Subject(s)
Fertilization in Vitro , Hemoperitoneum , Laparoscopy , Humans , Female , Pregnancy , Hemoperitoneum/surgery , Hemoperitoneum/etiology , Hemoperitoneum/diagnosis , Adult , Fertilization in Vitro/adverse effects , Omentum/surgery , Pregnancy, Abdominal/surgery , Pregnancy, Abdominal/diagnosis , Treatment Outcome
13.
Zhonghua Nei Ke Za Zhi ; 63(5): 521-524, 2024 May 01.
Article in Chinese | MEDLINE | ID: mdl-38715494

ABSTRACT

A 48-year-old male was admitted to Peking Union Medical College Hospital presented with intermittent fever for two years. The maximum body temperature was 39 ℃, and could spontaneously relieve. The efficacy of antibacterial treatment was poor. He had no other symptoms and positive signs. He had a significant weight loss, and the serum lactate dehydrogenase increased significantly. It was highly alert to be lymphoma, but bone marrow smear and pathology, and PET-CT had not shown obvious abnormalities. Considering high inflammatory indicators, increased ferritin and large spleen, the patient had high inflammatory status, and was treated with methylprednisolone. Then the patient's body temperature was normal, but the platelet decreased to 33×109/L. During hospitalization, he had suddenly hemoperitoneum and hemorrhagic shock. He was found spontaneous spleen rupture without obvious triggers, and underwent emergency splenectomy. The pathological diagnosis of spleen was diffuse large B-cell lymphoma.


Subject(s)
Fever of Unknown Origin , Hemoperitoneum , Positron Emission Tomography Computed Tomography , Humans , Male , Middle Aged , Fever of Unknown Origin/etiology , Fever of Unknown Origin/diagnosis , Positron Emission Tomography Computed Tomography/methods , Hemoperitoneum/etiology , Hemoperitoneum/diagnosis , Lymphoma, Large B-Cell, Diffuse/diagnosis , Splenectomy , Spleen/diagnostic imaging , Splenic Rupture/diagnosis , Splenic Rupture/etiology
14.
Dig Dis ; 42(5): 445-451, 2024.
Article in English | MEDLINE | ID: mdl-38663358

ABSTRACT

INTRODUCTION: Patients with liver cirrhosis develop thrombocytopenia and an increased risk of bleeding events after invasive procedures. Lusutrombopag, a thrombopoietin receptor agonist, can increase the platelet count. This study assessed whether lusutrombopag reduces the risk of hemoperitoneum following percutaneous radiofrequency ablation for hepatocellular carcinoma, compared with platelet transfusion. METHODS: Participants in the present study comprised patients with severe thrombocytopenia (platelet count <50,000/µL) enrolled between November 2012 and March 2020, excluding patients with idiopathic thrombocytopenia or anticoagulant use. Hemoperitoneum rate, hemostasis rate, hemoglobin reduction rate, rate of achieving a platelet count ≥50,000/µL, and increases in platelet count and factors contributing to hemoperitoneum were retrospectively analyzed. RESULTS: This study enrolled 41 patients, comprising 18 patients administered lusutrombopag and 23 patients who received platelet transfusion. The major hemoperitoneum rate after RFA was tend to be lower in the lusutrombopag group (0%) than in the platelet transfusion group (21.7%). All of the major hemoperitoneum was observed in the platelet transfusion group. Hemoglobin reduction rate was lower in the lusutrombopag group (-0.17%) than in the platelet transfusion group (6.79%, p = 0.013). Hemostasis rate was lower in the lusutrombopag group (0%) than in the platelet transfusion group (21.7%, p = 0.045). The rate of achievement of platelet counts ≥50,000/µL the day after RFA was higher in the lusutrombopag group (100%) than in the platelet transfusion group (60.9%, p = 0.005). CONCLUSION: Lusutrombopag may be able to perform RFA more safely with respect to the hemoperitoneum caused by percutaneous radiofrequency ablation compared with platelet transfusion.


Subject(s)
Carcinoma, Hepatocellular , Hemoperitoneum , Liver Neoplasms , Platelet Transfusion , Radiofrequency Ablation , Thiazoles , Thrombocytopenia , Humans , Male , Female , Carcinoma, Hepatocellular/surgery , Liver Neoplasms/surgery , Aged , Middle Aged , Radiofrequency Ablation/methods , Radiofrequency Ablation/adverse effects , Platelet Transfusion/methods , Platelet Transfusion/adverse effects , Retrospective Studies , Thiazoles/therapeutic use , Thrombocytopenia/etiology , Hemoperitoneum/etiology , Cinnamates/therapeutic use , Platelet Count
15.
J Am Vet Med Assoc ; 262(6): 1-3, 2024 Jun 01.
Article in English | MEDLINE | ID: mdl-38579752

ABSTRACT

OBJECTIVE: To describe the clinical presentation of a Thoroughbred filly with acute hemoperitoneum from a splenic source immediately after racing. ANIMAL: A 3-year-old Thoroughbred filly used for racing and that had raced shortly before presentation to the hospital. CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES: On presentation, the filly was quiet, alert, and responsive with a heart rate of 76 beats/min, pale mucous membranes, and absent borborygmi. All other physical examination parameters were within normal limits. Abdominal ultrasound was performed and revealed echogenic free abdominal fluid and a splenic hematoma. Abdominocentesis yielded sanguinous fluid with a PCV of 35%. The next day, repeat ultrasound revealed the splenic hematoma with capsular separation. TREATMENT AND OUTCOME: The filly was treated overnight with isotonic crystalloid fluids and aminocaproic acid (40 mg/kg, IV, slow bolus over 30 minutes followed by 20 mg/kg, IV, q 6 h), potassium penicillin (22,000 IU/kg, IV, q 6 h), gentamicin (6.6 mg/kg, IV, q 24 h), and omeprazole (4 mg/kg, PO, q 24 h). The lowest PCV obtained from the filly was 36 hours after presentation. The filly stabilized with medical treatment and was discharged to a farm for further recuperation. CLINICAL RELEVANCE: There are no published reports detailing hemoperitoneum of splenic origin in Thoroughbreds immediately after racing. Hemoperitoneum of splenic origin is not common in horses, with most cases of hemoperitoneum being secondary to acute trauma, neoplasia, parturition, or postoperative complications. While uncommon, this case raises awareness to another differential for a colicky horse immediately after racing.


Subject(s)
Hematoma , Hemoperitoneum , Horse Diseases , Animals , Horses , Hematoma/veterinary , Hematoma/etiology , Hemoperitoneum/veterinary , Hemoperitoneum/etiology , Horse Diseases/etiology , Female , Splenic Diseases/veterinary , Running
16.
Eur J Pediatr ; 183(7): 2893-2897, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38602530

ABSTRACT

Patients with immune thrombocytopenia (ITP) usually present with minor mucocutaneous bleeding. Corpus luteum hemorrhage (CLH) is generally asymptomatic but may, rarely, lead to severe intraperitoneal bleeding, mostly in patients with coagulation disorders. CLH causing intraperitoneal bleeding has only been described in few individuals with ITP. The objective of this retrospective observational study was to assess the clinical course and incidence of symptomatic CLH in adolescent females with newly diagnosed or chronic ITP. Additionally, a comprehensive literature review was conducted to scrutinize cases of pediatric female patients with ITP, complicated by CLH. We identified three patients with ITP and hemoperitoneum secondary to CLH. They presented with acute abdominal pain, had severe thrombocytopenia (platelet counts below 20 × 109/L), and required blood transfusions as well as ITP-directed therapy. All the patients were hemodynamically stable and did not require emergency surgical intervention.  Conclusion: CLH could potentially pose a significant complication in the context of adolescent females with ITP, requiring a strong index of suspicion to direct expedient therapy. What is Known: • Immune thrombocytopenia is typically associated with minor bleeding tendency. • Corpus luteum hemorrhage is generally asymptomatic; however, in women with bleeding disorders, it has the potential to result in substantial intra-abdominal bleeding. What is New: • Corpus luteum hemorrhage leading to intra-abdominal bleeding is a potential severe complication of immune thrombocytopenia in adolescent females.


Subject(s)
Corpus Luteum , Hemorrhage , Purpura, Thrombocytopenic, Idiopathic , Adolescent , Female , Humans , Hemoperitoneum/etiology , Hemorrhage/etiology , Hemorrhage/diagnosis , Hemorrhage/therapy , Ovarian Diseases/diagnosis , Ovarian Diseases/etiology , Purpura, Thrombocytopenic, Idiopathic/complications , Purpura, Thrombocytopenic, Idiopathic/therapy , Purpura, Thrombocytopenic, Idiopathic/diagnosis , Retrospective Studies
17.
Am J Case Rep ; 25: e943519, 2024 Apr 01.
Article in English | MEDLINE | ID: mdl-38556771

ABSTRACT

BACKGROUND Small bowel hematoma is a rare yet clinically significant condition characterized by the accumulation of blood within the mucosa and submucosa layers of the small intestine wall. It can lead to complications such as bowel obstruction, ischemia, perforation, and even hemorrhagic shock. The etiology of intramural small bowel hematoma is diverse, encompassing factors such as anticoagulant therapy, coagulopathies, vascular disorders, trauma, and underlying systemic conditions. CASE REPORT We present the case of a 67-year-old man with a history of aortic valve replacement who presented with intense abdominal pain. Physical examination revealed generalized abdominal tenderness and black stools upon rectal examination. Laboratory tests indicated coagulopathy with a prolonged thrombin time. A computed tomography scan confirmed the presence of an intramural small bowel hematoma and hemoperitoneum. The patient's condition significantly improved within 48 h under conservative management, including nasogastric tube insertion, continuous monitoring of gastric aspirate, nil per os status, intravenous fluids, and analgesics. Warfarin was temporarily stopped, and fresh frozen plasma was administered for anticoagulation reversal. Heparin infusion was initiated once the INR became within the therapeutic level. CONCLUSIONS The occurrence of spontaneous intramural small bowel hematoma, although rare, demands rapid diagnosis and prompt, well-coordinated management. This case underscores the pivotal role of multidisciplinary collaboration in providing a comprehensive assessment and a tailored approach to treatment. While conservative measures, including careful monitoring and supportive care, have demonstrated favorable outcomes, the consideration of surgical intervention remains crucial, particularly in severe cases.


Subject(s)
Anticoagulants , Warfarin , Male , Humans , Aged , Warfarin/adverse effects , Anticoagulants/adverse effects , Hemoperitoneum/chemically induced , Gastrointestinal Hemorrhage , Hematoma/chemically induced , Hematoma/complications , Hematoma/therapy , Abdominal Pain/etiology
18.
BMC Pregnancy Childbirth ; 24(1): 296, 2024 Apr 20.
Article in English | MEDLINE | ID: mdl-38643085

ABSTRACT

BACKGROUND: Ectopic pregnancies (EP) are a common pregnancy complication that's associated with significant morbidity and rarely mortality if not managed properly. Ultrasound examination forms the cornerstone of diagnosis of EP with some sonographic features occasionally not correlating with intraoperative findings. We set out to conduct an audit of EP managed surgically at our hospital for a 10-year period and discern the correlation and prediction of sonographic findings to intraoperative findings. METHODS: This study was designed as a Retrospective Observational Study based at the Aga Khan University Hospital (AKUH). Study population was all women admitted to AKUH with a diagnosis of ectopic pregnancy that was surgically managed between the period of January 1st 2011 to December 31st 2020. Analysis of data was done against a pre-set checklist. Descriptive statistics for continuous variables was calculated and tabulated in graphs and tables. SPSS version 22 was used for analysis of data. RESULTS: A total of 337 patients in this study had ultrasound findings. 99.7% (n = 336) of these patients had an intraoperatively confirmed EP. The commonest ultrasound finding was an adnexal mass in 97.1% (n = 309) of patients. These were confirmed surgically in 290 patients at the following locations: 76.6% (n = 222) were ampullary in location; 10.7% (n = 31) were fimbrial in location; 8.6%(n = 25) were isthmic in location; 2.4%(n = 7) were interstitial in location; 1%(n = 3) were abdominal in location; while 0.3% were located in the ovary(n = 1) or round ligament(n = 1) each. Interstitial EP on ultrasound were all (100%) confirmed in the same location intraoperatively, with ampullary EP also correlating fairly well with intraoperative location (75%). The distribution of location in the minor hemoperitoneum (HP) versus major HP groups were similar except for interstitial EP that increased from 1.4% in the minor HP group to 9.5% in the major HP group. CONCLUSION: In conclusion, ultrasonography still represents the best imaging modality for EP. The most common finding is usually an adnexal mass with no specific location. Most (99.7%) of the patients with this sonographic finding usually have a confirmed EP. Interstitial EP are the most well localized with ultrasound followed by ampullary EP. Furthermore, the presence of major (> 500mls) hemoperitoneum may act as an adjunct for diagnosis of an interstitial EP.


Subject(s)
Laparoscopy , Pregnancy Complications , Pregnancy, Interstitial , Pregnancy , Humans , Female , Hemoperitoneum/etiology , Ultrasonography/adverse effects , Laparoscopy/methods , Retrospective Studies
19.
J Nepal Health Res Counc ; 21(4): 689-691, 2024 Mar 31.
Article in English | MEDLINE | ID: mdl-38616605

ABSTRACT

Endometrioma is the localization of endometriosis in ovary which often develops as cyst. The condition can be complicated with infection, torsion and rupture leading to significant hemoperitoneum and ascites. We present here a 28-year female P2 L1 presented with the features of acute abdomen and severe anemia referred from other hospital where pain management was done. She had raised Ca-125 level, negative Urine Beta HCG and USG findings of left endometrioma with degenerating subserosal fibroid. The improvement of her general condition with analgesics was misleading however a static hematocrit level despite blood transfusion raised suspicion of ongoing pathology leading to blood loss and diagnostic paracentesis confirmed the hemoperitoneum while awaiting of CT report. She underwent Emergency Laparotomy which revealed hemoperitoneum of 2000ml and right ruptured ovarian endometrioma measuring and left ovarian cyst measuring 6x6 cm was noted. The postoperative period was uneventful. Keywords: Acute abdomen; case report; endometriosis; hemoperitoneum; ruptured endometrioma.


Subject(s)
Abdomen, Acute , Endometriosis , Female , Humans , Abdomen, Acute/etiology , Abdomen, Acute/surgery , Endometriosis/complications , Endometriosis/surgery , Hemoperitoneum/etiology , Hemoperitoneum/surgery , Laparotomy , Nepal , Adult
20.
BMJ Case Rep ; 17(3)2024 Mar 05.
Article in English | MEDLINE | ID: mdl-38442968

ABSTRACT

Spontaneous haemoperitoneum in pregnancy (SHiP) related to endometriosis is a rare and life-threatening complication. We report a case of a patient presenting to our department with major haemoperitoneum at 23+3 weeks of gestation due to a large rectovaginal endometriotic nodule. The patient required a midline laparotomy to evacuate 1 L of haemoperitoneum and achieve haemostasis. A large rectovaginal nodule was seen bleeding and was packed with haemostatic material and a large swab. After 24 hours, the swab was removed and haemostasis was confirmed. The patient was monitored very closely by a multidisciplinary team and the pregnancy was allowed to continue to try and achieve a better outcome for the baby and at 28 weeks of gestation, a girl was delivered in good condition via caesarean section.


Subject(s)
Endometriosis , Hemostatics , Female , Humans , Pregnancy , Cesarean Section , Endometriosis/complications , Endometriosis/diagnosis , Endometriosis/surgery , Hemoperitoneum/diagnostic imaging , Hemoperitoneum/etiology , Hemoperitoneum/surgery , Laparotomy , Infant, Newborn
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