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1.
PLoS One ; 16(6): e0252596, 2021.
Article in English | MEDLINE | ID: mdl-34086777

ABSTRACT

Recent studies have suggested that people's intent and ability to act also can influence their perception of their bodies' peripersonal space. Vice versa one could assume that the inability to reach toward and grasp an object might have an impact on the subject's perception of reaching distance. Here we tested this prediction by investigating body size and action capability perception of neurological patients suffering from arm paresis after stroke, comparing 32 right-brain-damaged patients (13 with left-sided arm paresis without additional spatial neglect, 10 with left-sided arm paresis and additional spatial neglect, 9 patients had neither arm paresis nor neglect) and 27 healthy controls. Nineteen of the group of right hemisphere stroke patients could be re-examined about five months after initial injury. Arm length was estimated in three different methodological approaches: explicit visual, explicit tactile/proprioceptive, and implicit reaching. Results fulfilled the working hypothesis. Patients with an arm paresis indeed perceived their bodies differently. We found a transient overestimation of the length of the contralesional, paretic arm after stroke. Body size and action capability perception for the extremities thus indeed seem to be tightly linked in humans.


Subject(s)
Paresis/psychology , Size Perception , Stroke/psychology , Aged , Arm/physiology , Body Size , Case-Control Studies , Female , Humans , Male , Middle Aged , Paresis/complications , Proprioception , Stroke/complications , Stroke/pathology
2.
J Neuroeng Rehabil ; 17(1): 94, 2020 07 14.
Article in English | MEDLINE | ID: mdl-32664980

ABSTRACT

BACKGROUND: Activities of daily living frequently require children to make rapid decisions and execute desired motor actions while inhibiting unwanted actions. Children with hemiparetic cerebral palsy due to perinatal stroke may have deficits in executive functioning in addition to motor impairments. The objective of this study was to use a robotic object hit and avoid task to assess the ability of children with hemiparetic cerebral palsy to make rapid motor decisions. METHODS: Forty-five children with hemiparetic cerebral palsy due to perinatal stroke and 146 typically developing children (both groups ages 6-19 years) completed a robotic object hit and avoid task using the Kinarm Exoskeleton. Objects of different shapes fell from the top of the screen with increasing speed and frequency. Children were instructed to hit two specific target shapes with either hand, while avoiding six distractor shapes. The number of targets and distractors hit were compared between children with hemiparetic cerebral palsy and typically developing children, accounting for age effects. We also compared performance to a simpler object hit task where there were no distractors. RESULTS: We found that children with hemiparetic cerebral palsy hit a greater proportion of total distractors compared to typically developing children, demonstrating impairments in inhibitory control. Performance for all children improved with age. Children with hemiparetic cerebral palsy hit a greater percentage of targets with each arm on the more complex object hit and avoid task compared to the simpler object hit task, which was not found in typically developing children. CONCLUSIONS: Children with hemiparetic cerebral palsy due to perinatal stroke demonstrated impairments in rapid motor decision making including inhibitory control, which can impede their ability to perform real-world tasks. Therapies that address both motor performance and executive functions are necessary to maximize function in children with hemiparetic cerebral palsy.


Subject(s)
Cerebral Palsy/rehabilitation , Decision Making , Robotics/methods , Stroke/congenital , Stroke/psychology , Activities of Daily Living , Adolescent , Aging/psychology , Cerebral Palsy/etiology , Cerebral Palsy/psychology , Child , Executive Function , Exoskeleton Device , Female , Humans , Inhibition, Psychological , Magnetic Resonance Imaging , Male , Paresis/psychology , Paresis/rehabilitation , Psychomotor Performance , Stroke/complications , Young Adult
4.
J Neurol Phys Ther ; 43(4): 197-203, 2019 10.
Article in English | MEDLINE | ID: mdl-31436612

ABSTRACT

BACKGROUND AND PURPOSE: The recovery patterns of upper limb (UL) impairment after stroke are established. Psychosocial factors such as belief that paretic UL recovery is possible, confidence, and motivation to use the paretic UL in everyday tasks are unexplored early after stroke. The purpose of this exploratory study was to characterize belief, confidence, and motivation to use the paretic UL in daily life, and self-perceived barriers to UL recovery over the first 24 weeks after stroke. METHODS: This was a longitudinal cohort study (N = 30) with 8 assessment sessions over the first 24 weeks after stroke. Belief, confidence, and motivation to use the paretic UL and self-perceived barriers were quantified via survey and analyzed using descriptive statistics. Change in the number of self-perceived barriers between weeks 2 and 24 was tested using a paired-samples t test. The relationship between UL capacity, depressive symptomatology, cognition, and each psychosocial factor was examined using Spearman rank-order correlation analyses. RESULTS: Twenty-two participants completed all study assessments. Belief, confidence, and motivation were high across the 24 weeks, with little variation. There was no difference between the average number of barriers from weeks 2 to 24. There was no relationship between the clinical measures and psychosocial factors at week 2, 12, or 24. DISCUSSION AND CONCLUSIONS: High levels of belief, confidence, and motivation appear consistent over the first 6 months after stroke. The lack of correlations between psychosocial factors and clinical measures suggests belief, confidence, and motivation may not be vulnerable to functional status early after stroke.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A283).


Subject(s)
Motivation/physiology , Paresis/rehabilitation , Self Concept , Stroke Rehabilitation/psychology , Stroke/physiopathology , Upper Extremity/physiopathology , Aged , Female , Humans , Longitudinal Studies , Male , Middle Aged , Paresis/etiology , Paresis/physiopathology , Paresis/psychology , Stroke/complications
5.
Exp Brain Res ; 237(8): 2123-2133, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31197412

ABSTRACT

Dynamic force modulation is critical for performing skilled bimanual tasks. Unilateral motor impairments after stroke contribute to asymmetric hand function. Here, we investigate the impact of stroke on dynamic bimanual force control and compare the contribution of each hand to a bimanual task. Thirteen chronic stroke and thirteen healthy control participants performed bimanual, isometric finger flexion during visually guided, force tracking of a trapezoidal trajectory with force increment and decrement phases. We quantified the accuracy and variability of total force from both hands. Individual hand contribution was quantified with the proportion of force contributed to total force and force variability of each hand. The total force output was 53.10% less accurate and 56% more variable in the stroke compared with the control group. The variability of total force was 91.10% greater in force decrement than increment phase. In stroke group, the proportion of force and force variability contributed by each hand differed across the two phases. During force decrement, the proportion of force contributed by the non-paretic hand reduced and force variability of the non-paretic hand increased, compared with the increment phase. The control group showed no differences in each hand's contribution across the two force phases. In conclusion, dynamic bimanual force modulation is impaired after stroke, with greater deficits in force decrement than force increment. The non-paretic and paretic hands adapt differentially to dynamic bimanual task constraints. During force decrement, the non-paretic hand preferentially assumes force modulation, while the paretic hand produces steady force to meet the force requirements.


Subject(s)
Functional Laterality/physiology , Hand Strength/physiology , Paresis/physiopathology , Psychomotor Performance/physiology , Stroke/physiopathology , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Muscle Contraction/physiology , Paresis/diagnosis , Paresis/psychology , Photic Stimulation/methods , Stroke/diagnosis , Stroke/psychology
6.
J Stroke Cerebrovasc Dis ; 28(4): 954-962, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30630757

ABSTRACT

OBJECTIVE: Fast and scaled muscular activation is required to recover body balance following an external perturbation. An issue open to investigation is the extent to which the cerebral hemisphere lesioned by stroke leads to asymmetric deficits in postural reactive responses. In this experiment, we aimed to compare muscular responses to unanticipated stance perturbations between individuals who suffered unilateral stroke either to the right or to the left cerebral hemisphere. METHODS: Stance perturbations were produced by releasing a load attached to the participant's trunk, inducing fast forward body oscillation. Electromyography was recorded from the gastrocnemius medialis and biceps femoris muscles. Muscular activation from age-matched healthy individuals was taken as reference. RESULTS: Analysis indicated that damage to the right hemisphere induced delayed activation onset, and lower rate and magnitude of activation of the proximal and distal muscles of the paretic leg. Those deficits were associated with stronger activation of the nonparetic leg. Comparisons between left hemisphere damage and controls showed deficits limited to activation of the biceps femoris of the paretic leg. Manipulation of visual information led to no significant effects on muscular responses. CONCLUSIONS: These results suggest that right cerebral hemisphere damage by stroke leads to more severe deficits in the generation of reactive muscular responses to stance perturbation than damage to the left cerebral hemisphere regardless of visual information.


Subject(s)
Cerebrum/physiopathology , Functional Laterality , Muscle, Skeletal/innervation , Paresis/physiopathology , Postural Balance , Sensation Disorders/physiopathology , Stroke/physiopathology , Visual Perception , Aged , Aged, 80 and over , Case-Control Studies , Disability Evaluation , Electromyography , Female , Humans , Male , Middle Aged , Paresis/diagnosis , Paresis/etiology , Paresis/psychology , Photic Stimulation , Sensation Disorders/diagnosis , Sensation Disorders/etiology , Sensation Disorders/psychology , Stroke/complications , Stroke/diagnosis , Stroke/psychology
7.
Disabil Rehabil ; 41(13): 1545-1551, 2019 06.
Article in English | MEDLINE | ID: mdl-29564912

ABSTRACT

PURPOSE: To investigate the relation between observed and perceived upper limb motor function in patients with chronic stroke. MATERIAL AND METHODS: We investigated 32 patients at six months after stroke with the Fugl-Meyer Assessment (observed function) and hand subscale of the Stroke Impact Scale (perceived function). Spearman correlation was calculated to relate observed and perceived function. Through cut-off scores, we divided our sample in low (Fugl-Meyer Assessment <31/66) and good observed function, and low (hand subscale of Stroke Impact Scale <61/100) and good perceived function. Scatterplot and hierarchical clustering analysis was conducted to detect distinct groups. RESULTS: A strong positive relation was found between observed and perceived function (r = 0.84). Three groups could be identified; a "low match group" of patients with low observed and low perceived function (n = 11, 34%), a "good match group" containing patients with good observed and good perceived function (n = 15, 47%), and a "mismatch group" comprising patients with good observed but low perceived function (n = 6, 19%). CONCLUSIONS: In our chronic sample, one in five patients showed good upper limb observed but low perceived function. Measuring both observed and perceived arm and hand function seems warranted together with considering a differential therapy approach for the distinct groups. Implications for rehabilitation A considerable group of patients in the chronic phase post-stroke have good motor function in their affected upper limb, but nevertheless perceive a restricted ability. In order to identify a mismatch in people with chronic stroke, both observed and perceived upper limb motor function should be assessed. Besides common measurement tools for observed function like the Fugl-Meyer Assessment, perceived function can be evaluated by means of the hand function section of the Stroke Impact Scale. For patients with good observed but low perceived function, an additional rehabilitation strategy should be considered, potentially including awareness of ability and a self-efficacy approach.


Subject(s)
Paresis/psychology , Stroke Rehabilitation/psychology , Stroke , Upper Extremity/physiopathology , Aged , Diagnostic Self Evaluation , Disability Evaluation , Female , Humans , Male , Middle Aged , Outcome Assessment, Health Care , Paresis/etiology , Paresis/physiopathology , Paresis/rehabilitation , Perception , Recovery of Function , Stroke/complications , Stroke/physiopathology
8.
Arch Phys Med Rehabil ; 99(9): 1913-1916, 2018 09.
Article in English | MEDLINE | ID: mdl-29408483

ABSTRACT

OBJECTIVE: To compare self-reported with sensor-measured upper limb (UL) performance in daily life for individuals with chronic (≥6mo) UL paresis poststroke. DESIGN: Secondary analysis of participants enrolled in a phase II randomized, parallel, dose-response UL movement trial. This analysis compared the accuracy and consistency between self-reported UL performance and sensor-measured UL performance at baseline and immediately post an 8-week intensive UL task-specific intervention. SETTING: Outpatient rehabilitation. PARTICIPANTS: Community-dwelling individuals with chronic (≥6mo) UL paresis poststroke (N=64). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Motor Activity Log amount of use scale and the sensor-derived use ratio from wrist-worn accelerometers. RESULTS: There was a high degree of variability between self-reported UL performance and the sensor-derived use ratio. Using sensor-based values as a reference, 3 distinct categories were identified: accurate reporters (reporting difference ±0.1), overreporters (difference >0.1), and underreporters (difference <-0.1). Five of 64 participants accurately self-reported UL performance at baseline and postintervention. Over half of participants (52%) switched categories from pre-to postintervention (eg, moved from underreporting preintervention to overreporting postintervention). For the consistent reporters, no participant characteristics were found to influence whether someone over- or underreported performance compared with sensor-based assessment. CONCLUSIONS: Participants did not consistently or accurately self-report UL performance when compared with the sensor-derived use ratio. Although self-report and sensor-based assessments are moderately associated and appear similar conceptually, these results suggest self-reported UL performance is often not consistent with sensor-measured performance and the measures cannot be used interchangeably.


Subject(s)
Accelerometry/statistics & numerical data , Paresis/psychology , Self Report/statistics & numerical data , Stroke Rehabilitation/statistics & numerical data , Stroke/complications , Activities of Daily Living , Aged , Female , Humans , Independent Living , Male , Middle Aged , Paresis/etiology , Paresis/physiopathology , Reproducibility of Results , Stroke/physiopathology , Stroke/psychology , Treatment Outcome , Wrist/physiopathology
9.
Arch Phys Med Rehabil ; 99(11): 2168-2174, 2018 11.
Article in English | MEDLINE | ID: mdl-29476713

ABSTRACT

OBJECTIVES: To compare the effects of conventional core stabilization and dynamic neuromuscular stabilization (DNS) on anticipatory postural adjustment (APA) time, balance performance, and fear of falls in chronic hemiparetic stroke. DESIGN: Two-group randomized controlled trial with pretest-posttest design. SETTING: Hospital rehabilitation center. PARTICIPANTS: Adults with chronic hemiparetic stroke (N=28). INTERVENTIONS: Participants were randomly divided into either conventional core stabilization (n=14) or DNS (n=14) groups. Both groups received a total of 20 sessions of conventional core stabilization or DNS training for 30 minutes per session 5 times a week during the 4-week period. MAIN OUTCOME MEASURES: Electromyography was used to measure the APA time for bilateral external oblique (EO), transverse abdominis (TrA)/internal oblique (IO), and erector spinae (ES) activation during rapid shoulder flexion. Trunk Impairment Scale (TIS), Berg Balance Scale (BBS), and Falls Efficacy Scale (FES) were used to measure trunk movement control, balance performance, and fear of falling. RESULTS: Baseline APA times were delayed and fear of falling was moderately high in both the conventional core stabilization and DNS groups. After the interventions, the APA times for EO, TrA/IO, and ES were shorter in the DNS group than in the conventional core stabilization group (P<.008). The BBS and TIS scores (P<.008) and the FES score (P<.003) were improved compared with baseline in both groups, but FES remained stable through the 2-year follow-up period only in the DNS group (P<.003). CONCLUSIONS: This is the first clinical evidence highlighting the importance of core stabilization exercises for improving APA control, balance, and fear of falls in individuals with hemiparetic stroke.


Subject(s)
Accidental Falls/prevention & control , Exercise Therapy/methods , Paresis/rehabilitation , Postural Balance/physiology , Stroke Rehabilitation/methods , Abdominal Muscles/physiopathology , Abdominal Oblique Muscles/physiopathology , Aged , Anticipation, Psychological , Chronic Disease , Electromyography , Fear , Female , Humans , Male , Middle Aged , Muscle Stretching Exercises/methods , Paraspinal Muscles/physiopathology , Paresis/physiopathology , Paresis/psychology , Single-Blind Method , Stroke/complications , Stroke/physiopathology , Stroke/psychology , Torso/physiopathology , Treatment Outcome
10.
Am J Phys Med Rehabil ; 97(5): e37-e41, 2018 05.
Article in English | MEDLINE | ID: mdl-29095167

ABSTRACT

Upper limb paresis, common in many neurological conditions, is a major contributor of long-term disability and decreased quality of life. Evidence shows that repetitive, bilateral arm movement improves upper limb coordination after neurological injury. However, it is difficult to integrate upper limb interventions into very early rehabilitation of critically ill neurological patients because of patient arousal and medical acuity. This report describes the safety and feasibility of bilateral upper limb cycling in critically ill neurological patients with bilateral or unilateral paresis. Patients were included in this pilot observational series if they used upper limb cycle ergometry with occupational therapy while in the neurocritical care unit between May and August 2016. Patient demographics, neurological function, and hemodynamic status were recorded precycling and postcycling. Cycling parameters including duration and active and/or passive cycling were collected. No significant changes in hemodynamic or respiratory status were noted postintervention. No adverse effects or safety events were noted. In this series, upper limb cycle ergometry was a safe and feasible intervention for early rehabilitation in critically ill patients in the neurocritical care unit. Future studies will prospectively measure the impact of early upper limb cycle ergometry on neurological recovery and functional outcome in this population.


Subject(s)
Bicycling , Ergometry/methods , Exercise Therapy/methods , Paresis/rehabilitation , Polyneuropathies/rehabilitation , Aged , Cognition , Cognitive Dysfunction/etiology , Cognitive Dysfunction/rehabilitation , Critical Illness/rehabilitation , Feasibility Studies , Female , Humans , Male , Middle Aged , Muscle Weakness/etiology , Muscle Weakness/psychology , Muscle Weakness/rehabilitation , Paresis/etiology , Paresis/psychology , Pilot Projects , Polyneuropathies/complications , Polyneuropathies/psychology , Quality of Life , Recovery of Function , Time Factors , Treatment Outcome , Upper Extremity/physiopathology
11.
Rehabil Psychol ; 62(4): 509-515, 2017 Nov.
Article in English | MEDLINE | ID: mdl-29265871

ABSTRACT

OBJECTIVE: Depressive symptoms after stroke have been associated with negative outcomes, including poorer functional ability, less efficient use of rehabilitation services, decreased quality of life, and increased mortality. It has been anecdotally noted that depressive symptoms do not limit motor recovery in patients who undergo Constraint-Induced Movement Therapy (CIMT), an efficacious intervention for chronic poststroke hemiparesis. Here we analyze depressive symptom and motor scores from 40 participants who received CIMT in 2 previously published studies. METHOD: Adults more than 1-year after stroke with mild to moderate upper-extremity hemiparesis completed the Zung Self-Rating Depression Scale and Motor Activity Log (MAL) before and after CIMT. We used regression analysis to test whether Zung scores predicted response to CIMT and paired t tests to test whether depressive symptoms changed from pre- to posttreatment. RESULTS: Pretreatment Zung score did not predict outcome on the MAL Arm Use scale, ΔR2 (1, 30) = 0.004, p = .19, after controlling for pretreatment MAL scores. Additionally, participants had a small but statistically significant decrease in Zung score, t(39) = 3.0, p = .005, mean change = -3.6. CONCLUSION: These results suggest that depressive symptoms do not significantly limit motor recovery in patients treated with CIMT for chronic poststroke hemiparesis. Additionally, treatment with CIMT may improve depressive symptoms. (PsycINFO Database Record


Subject(s)
Depression/complications , Depression/psychology , Paresis/etiology , Paresis/therapy , Stroke Rehabilitation , Stroke/complications , Female , Humans , Male , Middle Aged , Paresis/psychology , Physical Therapy Modalities , Retrospective Studies , Severity of Illness Index , Stroke/physiopathology , Stroke/psychology , Treatment Outcome , Upper Extremity/physiopathology
12.
Restor Neurol Neurosci ; 35(5): 537-545, 2017.
Article in English | MEDLINE | ID: mdl-28984620

ABSTRACT

BACKGROUND: After stroke, the learned non-use of a paretic arm is a major obstacle to the improvement of hand function. OBJECTIVE: We examined whether patients with a central paresis could profit from applying the self-regulation strategy of making if-then plans that specify situational triggers to using the paretic arm. METHOD: Seventeen stroke patients with a mild to moderate hand paresis were asked to perform a Simon task which is commonly used to study the enhanced executive control needed when there is a mismatch between stimulus (e.g., color) and response (e.g., location) features. We examined whether patients with hemiparesis would be able to reduce the Simon effect (i.e., responding slower to mismatched as compared to matched stimulus and response features) by creating new stimulus-response associations via if-then plans. RESULTS: A significant Simon effect was observed in both the affected and the non-affected arm for control trials. However, there was no longer a significant Simon effect for the critical trials prepared by forming if-then plans. This led to a significant stimulus×compatibility interaction effect for the affected arm and a marginally significant interaction effect for the non-affected arm. Making if-then plans was effective for eliminating or at least reducing the Simon effect for the affected and the non-affected arm, respectively. CONCLUSION: This observation opens a potential new route to improving stroke rehabilitation. If-then plans may qualify as a viable strategy to overcome the learned non-use of the affected arm. Further research is now required to develop and test therapeutic measures based on this proof-of-principle.


Subject(s)
Learning , Motor Activity , Paresis/rehabilitation , Stroke Rehabilitation , Stroke/complications , Arm/physiopathology , Executive Function , Female , Hand/physiopathology , Humans , Male , Middle Aged , Paresis/etiology , Paresis/physiopathology , Paresis/psychology , Proof of Concept Study , Reaction Time , Recovery of Function , Stroke/physiopathology , Stroke/psychology
13.
Neurorehabil Neural Repair ; 31(8): 769-780, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28803535

ABSTRACT

BACKGROUND: Robots that physically assist movement are increasingly used in rehabilitation therapy after stroke, yet some studies suggest robotic assistance discourages effort and reduces motor learning. OBJECTIVE: To determine the therapeutic effects of high and low levels of robotic assistance during finger training. METHODS: We designed a protocol that varied the amount of robotic assistance while controlling the number, amplitude, and exerted effort of training movements. Participants (n = 30) with a chronic stroke and moderate hemiparesis (average Box and Blocks Test 32 ± 18 and upper extremity Fugl-Meyer score 46 ± 12) actively moved their index and middle fingers to targets to play a musical game similar to GuitarHero 3 h/wk for 3 weeks. The participants were randomized to receive high assistance (causing 82% success at hitting targets) or low assistance (55% success). Participants performed ~8000 movements during 9 training sessions. RESULTS: Both groups improved significantly at the 1-month follow-up on functional and impairment-based motor outcomes, on depression scores, and on self-efficacy of hand function, with no difference between groups in the primary endpoint (change in Box and Blocks). High assistance boosted motivation, as well as secondary motor outcomes (Fugl-Meyer and Lateral Pinch Strength)-particularly for individuals with more severe finger motor deficits. Individuals with impaired finger proprioception at baseline benefited less from the training. CONCLUSIONS: Robot-assisted training can promote key psychological outcomes known to modulate motor learning and retention. Furthermore, the therapeutic effectiveness of robotic assistance appears to derive at least in part from proprioceptive stimulation, consistent with a Hebbian plasticity model.


Subject(s)
Exercise Therapy/methods , Fingers/physiopathology , Motor Activity/physiology , Paresis/rehabilitation , Robotics , Stroke Rehabilitation/methods , Double-Blind Method , Exercise Therapy/instrumentation , Female , Follow-Up Studies , Humans , Learning , Male , Middle Aged , Models, Neurological , Motivation , Movement/physiology , Music , Neuronal Plasticity/physiology , Paresis/etiology , Paresis/physiopathology , Paresis/psychology , Recovery of Function , Stroke/complications , Stroke/physiopathology , Stroke/psychology , Stroke Rehabilitation/instrumentation , Treatment Outcome , Video Games
14.
J Neuroeng Rehabil ; 14(1): 57, 2017 06 15.
Article in English | MEDLINE | ID: mdl-28615080

ABSTRACT

BACKGROUND: Locomotor strategies for obstacle circumvention require appropriate postural coordination that depends on sensorimotor integration within the central nervous system. It is not known how these strategies are affected by a stroke. The objective of this study was to contrast postural coordination strategies used for obstacle circumvention between post-stroke participants (n = 12) and healthy controls (n = 12). METHODS: Participants walked towards a target in a virtual environment (11 × 8 m room) with cylindrical obstacles that were stationary or approaching from head-on, or diagonally 30° left/right. RESULTS: Two stepping strategies for obstacle circumvention were identified: 1) side step: increase in step width by the foot ipsilateral to the side of circumvention; 2) cross step: decrease in step width by the foot contralateral to the side of circumvention. The side step strategy was favoured by post-stroke individuals in circumventing stationary and head-on approaching obstacles. In circumventing diagonally approaching obstacles, healthy controls generally veered opposite to obstacle approach (>60% trials), whereas the majority of post-stroke participants (7/12) veered to the same side of obstacle approach (Vsame). Post-stroke participants who veered to the opposite side (Vopp, 5/12) were more independent and faster ambulators who favoured the side step strategy in circumventing obstacles approaching from the paretic side and cross step strategy for obstacles approaching from the non-paretic side. Vsame participants generally favoured the side step strategy for both diagonal approaches. Segmental rotation amplitudes and latencies were largest in the Vsame group, and significantly greater in post-stroke participants than controls for all obstacle conditions. All participants initiated circumvention with the feet followed by the pelvis and thorax, demonstrating a caudal-rostral sequence of reorientation. CONCLUSION: Postural coordination strategies for obstacle circumvention were altered post stroke, depending on the residual or restored functional abilities. Segmental re-orientations are also affected by the motion and direction of obstacle.


Subject(s)
Locomotion , Posture , Stroke/psychology , Adult , Aged , Female , Foot/physiopathology , Functional Laterality , Humans , Male , Middle Aged , Orientation , Paresis/physiopathology , Paresis/psychology , Paresis/rehabilitation , Psychomotor Performance , Stroke Rehabilitation/methods , User-Computer Interface , Walking
15.
Cogn Behav Neurol ; 30(1): 37-41, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28323685

ABSTRACT

Reports of involuntary ipsilateral movements after a stroke are rare, and none have described a patient with both an instinctive grasp reaction and tremor-like movement ipsilateral to the acute stroke lesion. We here report such a patient. A 76-year-old right-handed woman with a past history of left thalamic hemorrhage developed left hemiparesis, an instinctive grasp reaction, and a peculiar involuntary movement of her right arm. This involuntary movement was stereotyped and sometimes rhythmical, with a groping or picking-like action. The lesion responsible for her motor deficits was a broad infarct in the right internal carotid artery territory. We suggest that her characteristic involuntary tremor-like movement was a variation of the instinctive grasp reaction caused by an ipsilateral ischemic lesion that included the frontal lobe. We illustrate her movements with a video, Supplemental Digital Content 1, http://links.lww.com/CBN/A65.


Subject(s)
Brain Ischemia/psychology , Hand Strength , Stroke/psychology , Tremor/psychology , Aged , Arm , Brain Ischemia/complications , Carotid Artery, Internal/diagnostic imaging , Cerebral Infarction/diagnostic imaging , Dyskinesias , Electroencephalography , Fatal Outcome , Female , Frontal Lobe/diagnostic imaging , Functional Laterality , Humans , Magnetic Resonance Imaging , Paresis/etiology , Paresis/psychology , Stereotyped Behavior , Stroke/complications , Tremor/etiology
16.
Neurorehabil Neural Repair ; 31(2): 178-189, 2017 02.
Article in English | MEDLINE | ID: mdl-27789762

ABSTRACT

BACKGROUND AND OBJECTIVE: Stroke rehabilitation assumes motor learning contributes to motor recovery, yet motor learning in stroke has received little systematic investigation. Here we aimed to illustrate that despite matching levels of performance on a task, a trained patient should not be considered equal to an untrained patient with less impairment. METHODS: We examined motor learning in healthy control participants and groups of stroke survivors with mild-to-moderate or moderate-to-severe motor impairment. Participants performed a series of isometric contractions of the elbow flexors to navigate an on-screen cursor to different targets, and trained to perform this task over a 4-day period. The speed-accuracy trade-off function (SAF) was assessed for each group, controlling for differences in self-selected movement speeds between individuals. RESULTS: The initial SAF for each group was proportional to their impairment. All groups were able to improve their performance through skill acquisition. Interestingly, training led the moderate-to-severe group to match the untrained (baseline) performance of the mild-to-moderate group, while the trained mild-to-moderate group matched the untrained (baseline) performance of the controls. Critically, this did not make the two groups equivalent; they differed in their capacity to improve beyond this matched performance level. Specifically, the trained groups had reached a plateau, while the untrained groups had not. CONCLUSIONS: Despite matching levels of performance on a task, a trained patient is not equal to an untrained patient with less impairment. This has important implications for decisions both on the focus of rehabilitation efforts for chronic stroke, as well as for returning to work and other activities.


Subject(s)
Learning , Motor Skills , Movement Disorders/rehabilitation , Paresis/rehabilitation , Stroke Rehabilitation , Stroke/complications , Adult , Aged , Female , Functional Laterality , Humans , Male , Mental Status Schedule , Middle Aged , Movement Disorders/etiology , Movement Disorders/physiopathology , Movement Disorders/psychology , Paresis/etiology , Paresis/physiopathology , Paresis/psychology , Robotics , Severity of Illness Index , Stroke/physiopathology , Stroke/psychology , Upper Extremity/physiopathology , Young Adult
17.
Neurorehabil Neural Repair ; 31(2): 133-146, 2017 02.
Article in English | MEDLINE | ID: mdl-27542986

ABSTRACT

BACKGROUND: Upper limb (UL) poststroke hemiparesis commonly leads to chronic disability. Despite moderate-to-good clinical recovery, many patients with UL hemiparesis still do not fully use their arm in daily tasks. Decreased arm use may be related to deficits in performance of more complex movement than what is usually assessed clinically. OBJECTIVE: To identify differences between poststroke and nondisabled control subjects in making complex corrective movements to avoid an obstacle in the reaching path. METHODS: Subjects rapidly reached for a juice bottle on a refrigerator shelf with their hemiparetic or dominant (controls) arm viewed in a large-screen projected 3D virtual environment. In random trials, a sliding door partially obstructed the reaching path. A successful trial was one in which subjects touched the bottle without their arm or hand hitting the door. RESULTS: Fewer participants with stroke (12%) were successful at a 65% success rate in avoiding the door compared to controls (42%). Subjects with stroke also initiated corrections later (further) in the reaching path (100.7 ± 77.6 mm) compared to controls (51.6 ± 31.0 mm) resulting in a reduced margin of error. While both groups used similar endpoint movement strategies for obstructed reaching, subjects with stroke used less elbow and more trunk movement. Participants who reported being more confident using their hemiparetic arm had higher success rates. CONCLUSION: Arm movement deficits can be identified when complex tasks are evaluated. Deficits in higher-order motor function such as obstacle avoidance behavior may decrease actual arm use in individuals with mild-to-moderate hemiparesis and should be evaluated in routine clinical practice.


Subject(s)
Avoidance Learning , Motor Activity , Paresis/physiopathology , Stroke/physiopathology , Upper Extremity , Activities of Daily Living/psychology , Adaptation, Psychological , Aged , Biomechanical Phenomena , Brain Ischemia/complications , Brain Ischemia/physiopathology , Brain Ischemia/psychology , Cerebral Hemorrhage/complications , Cerebral Hemorrhage/physiopathology , Cerebral Hemorrhage/psychology , Female , Functional Laterality , Humans , Male , Middle Aged , Motor Activity/physiology , Paresis/etiology , Paresis/psychology , Recovery of Function , Severity of Illness Index , Stroke/complications , Stroke/psychology , Upper Extremity/physiopathology , User-Computer Interface
18.
Trials ; 17(1): 523, 2016 10 27.
Article in English | MEDLINE | ID: mdl-27788679

ABSTRACT

BACKGROUND: After a lesion to the central nervous system, many patients suffer from reduced walking capability. In the first rehabilitation phase, repeated walking exercises facilitate muscular strength and stimulate brain plasticity and motor relearning. However, marked limping, an unsteady gait, and poor management of obstacle clearance may persist, which increases a patient's risk of falling. Gait training with augmented reality has been recommended to improve gait coordination. The objective of this study is to test whether a gait rehabilitation program using augmented reality is superior to a conventional treadmill training program of equivalent intensity. METHODS/DESIGN: The GASPAR trial (Gait Adaptation for Stroke Patients with Augmented Reality) is a pragmatic, parallel-arm, single-center, nonblind, superiority randomized control trial in neurorehabilitation. The setting is a rehabilitation clinic in Switzerland. The planned number of participants is 70-100. The intervention uses instrumented treadmills equipped with projectors that display shapes on the walking surface. The principle is that patients must adapt their gait to the image that unfolds in front of them. Specific exercises for gait symmetry, coordination enhancement, and gait agility are provided. The program includes twenty 30-min sessions spanning 4 weeks. The comparator group receives standard treadmill training of a similar frequency and intensity. The main outcome to be measured in the trial is walking speed, which is assessed with the 2-min Walk Test. Moreover, gait parameters are recorded during the gait training sessions. Other outcomes are balance control (Berg Balance Scale) and the fear of falling (Falls Efficacy Scale). The statistical analyses will compare the baseline assessment for each participant (before the intervention) with a post-intervention assessment (taken a few days after the end of the program). Furthermore, a follow-up assessment will take place 3 months after discharge. DISCUSSION: The study results will provide new knowledge about recovery in neurological patients and will contribute to the design of better rehabilitation programs to accompany this process. The findings will also help health care funders to decide whether treadmills equipped with augmented reality capabilities are a worthwhile investment. TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT02808078 , registered on 16 June 2016.


Subject(s)
Brain Injuries, Traumatic/rehabilitation , Exercise Therapy/methods , Feedback, Psychological , Gait , Paresis/rehabilitation , Spinal Cord Injuries/rehabilitation , Stroke Rehabilitation/methods , Stroke/therapy , Visual Perception , Walking , Adaptation, Psychological , Brain Injuries, Traumatic/diagnosis , Brain Injuries, Traumatic/physiopathology , Brain Injuries, Traumatic/psychology , Clinical Protocols , Cues , Disability Evaluation , Humans , Motor Activity , Paresis/diagnosis , Paresis/physiopathology , Paresis/psychology , Postural Balance , Recovery of Function , Research Design , Spinal Cord Injuries/diagnosis , Spinal Cord Injuries/physiopathology , Spinal Cord Injuries/psychology , Stroke/diagnosis , Stroke/physiopathology , Stroke/psychology , Switzerland , Time Factors , Treatment Outcome , Walk Test
19.
J Hand Ther ; 29(4): 507-514, 2016.
Article in English | MEDLINE | ID: mdl-27665394

ABSTRACT

Functional electrical stimulation (FES) has shown to improve motor function of the affected side in stroke patients; however, the effects of FES on proprioception, the functional recovery of the paretic upper limb, and the patient quality of life (QoL) are not clear. The aim of the current case report was to determine whether FES can improve joint position sense and the scores on measurements of upper limb function and a QoL survey. The participant was assessed before and after 10 consecutive intervention sessions; in addition, the patient performed the training tasks in the workstation assisted by the FES device. Improvements in angles and time only in the affected wrist and enhancement in the Action Research Arm Test scores for both upper limbs were found after FES intervention. In addition, the patient's health-related QoL measurements improved. FES could ameliorate the proprioceptive deficit and the activity limitations of a stroke survivor. OXFORD LEVEL OF EVIDENCE: 3b; individual case control study.


Subject(s)
Electric Stimulation Therapy/methods , Paresis/rehabilitation , Quality of Life , Stroke/complications , Upper Extremity/physiopathology , Disability Evaluation , Female , Follow-Up Studies , Humans , Middle Aged , Motor Skills/physiology , Paresis/etiology , Paresis/psychology , Proprioception/physiology , Recovery of Function/physiology , Stroke/diagnosis , Stroke/psychology , Stroke Rehabilitation/methods , Task Performance and Analysis , Treatment Outcome
20.
Rehabil. integral (Impr.) ; 11(1): 33-39, jun. 2016. tab
Article in Spanish | LILACS | ID: biblio-869328

ABSTRACT

Introduction: Cerebral Palsy (CP) is the most prevalent diagnosis in Teleton Institutes in Chile. The syndrome is characterized by a non progressive brain lesion that causes an impact in different areas of development. It is our interest to study how adolescents with CP symbolize this experience, given that identity formation and self representation are key aspects during this developmental stage. Objective: To describe meanings build in mild hemiplegic CP, from 12 to 16 years of age, attending Teleton Institute Temuco. Subjects and Method: Qualitative study, exploratory descriptive type, phenomenological. Data were gathered through semi-structured interviews applied to 10 adolescents, and a focus group with 4 of these, both experiences included patients from 12 to 16 years with mild hemiplegic CP and intellectual capacity to answer medium complexity questions. Results: Adolescents describe hemiplegia as a condition characterized by physical differences, as a disability and a challenge, they recognize its origins and the beliefs they perceive in others. It is not considered an illness and as implications they count experiences, needs and problems that are part of this condition, however, they are able to reformulate this experience, holding a positive and resilient view towards their condition. Conclusion: Adolescents express similitudes between the concept of hemiplegia and disability; they point it as a complex experience that brings negative consequences as well as learning experiences. They are finally able to reformulate it and experience it as a challenge.


Introducción: La parálisis cerebral (PC) es el diagnóstico con mayor incidencia en los Institutos Teletón (IT) del país. Este síndrome está determinado por una lesión cerebral de carácter no progresivo, que puede tener implicancias en los distintos ámbitos del desarrollo. El cómo simbolizan esta experiencia adolescentes con PC tipo hemiparesia, es de nuestro interés, considerando que la formación de la identidad y la representación de sí mismos en esta etapa son claves. Objetivo: Describir los significados construidos en torno a la PC tipo hemiparesia leve, de adolescentes de 12 a 16 años de ITTemuco. Usuarios y Método: Investigación cualitativa de tipo exploratorio descriptivo, fenomenológica. Recolección de datos a través de entrevista semi estructurada aplicada a 10 usuarios y un grupo focal realizado con 4 participantes, en ambas instancias con la participación de jóvenes de 12 a 16 años con PC de tipo hemiparesia leve y capacidad cognitiva para responder a preguntas de mediana complejidad. Resultados: Los jóvenes definen la hemiparesia como una condición caracterizada por diferencias físicas, como una discapacidad y un desafío, reconocen sus orígenes y las creencias que perciben en otros. No es considerada como enfermedad y como implicancias indican vivencias, experiencias, necesidades y problemas que conlleva esta condición, no obstante, logran re-significar esta experiencia manteniendo una mirada positiva y resiliente en relación a su condición. Conclusión: Los adolescentes expresan similitudes entre el concepto de hemiparesia y discapacidad, las significan como una experiencia compleja que trae consecuencias negativas así como aprendizajes, logrando re-significarla y vivenciarla finalmente como un desafío.


Subject(s)
Humans , Male , Adolescent , Female , Child , Quality of Life/psychology , Cerebral Palsy/psychology , Self Concept , Paresis/psychology , Qualitative Research
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