Colorectal intussusception with rectal prolapse related to cecal lipoma in adult: A rare case report and review of the literature.

Colonic intussusception due to lipoma is extremely rare. Very few cases were reported in the literature of cecal lipoma leading to the intussusception of the whole proximal colon till the rectum. We report a rare case of a 39-year-old female patient with cecal lipoma causing colo-colonic intussusception involving the entire length of the proximal colon and the overall mass prolapsed into the pelvis that could be palpated in rectal examination. The case presented with a giant mass with clinical manifestations of obstruction. An extended right hemicolectomy and end ileostomy were performed due to intestinal dilation and intra-abdominal contamination. To the best of our knowledge, this is the second case of cecal lipoma leading to intussusception of the whole proximal colon till to the rectum reported in the relevant literature. Whenever a colonic mass results in intussusception, the incidence of malignancy is slightly higher (60%), so a proper oncological resection should be performed if the pathology is not known preoperatively.

Effects of glutamine and curcumin on bacterial translocation in jaundiced rats.

AIM: To investigate the effect of curcumin on bacterial translocation and oxidative damage in an obstructive jaundice model and compare the results to glutamine, an agent known to be effective and clinically used. METHODS: Twenty-four female Wistar-Albino rats, weighing 200-250 g, were randomly divided into three groups (8 in each group). After ligation of the common bile duct in all animals, Group I received oral normal saline, Group II received oral glutamine and Group III received oral curcumin for seven days. Blood samples via cardiac puncture, tissue samples (terminal ileum, liver and mesenteric lymph node) and peritoneal fluid were obtained from the animals at the time of death to investigate bacterial translocation and oxidative damage. RESULTS: We observed that both glutamine and curcumin reduced bacterial translocation in blood, hepatocellular damage, plasma cytokine levels, oxidative tissue damage and apoptosis significantly compared to the control group. Additionally, glutamine showed protective effects on ileal epithelium and reduced villus atrophy. CONCLUSION: On the basis of these findings, both curcumin and glutamine are thought to be effective in preventing or reducing bacterial translocation and oxidative damage in obstructive jaundice.

Esophageal stent migration can lead to intestinal obstruction.

BACKGROUND: Self-expanding metallic stents are the devices of choice in the treatment of malign or benign strictures of the esophagus. Stent migration is a well-known complication of this procedure. AIMS: We report a case of intestinal obstruction caused by esophageal stent migration, in which surgical intervention was used. METHODS: A 65-year-old woman, who had a medical history of gastric cancer operations and esophageal stent applications, was admitted to our emergency department with a 48-hour history of abdominal pain, nausea and vomiting. An emergency laparotomy was performed and the migrated stent causing intestinal obstruction was removed. RESULTS: The patient recovered without incident and was discharged on postoperative day 3. CONCLUSION: This case illustrates that esophageal stent migration has to be considered as a potential life-threatening complication.