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1.
Med Sante Trop ; 29(4): 402-408, 2019 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-31884995

RESUMO

The objective of our study was to evaluate the medico-surgical management of Buruli ulcer (BU) in the BU Screening and Treatment Center (CDTUB) of Allada in Benin. This retrospective and descriptive study retrospectively reviewed records of patients seen from 2010 to 2014 at the CDTUB of Allada. It included patients diagnosed with BU according to WHO epidemiological and clinical criteria as well as laboratory results and who were treated according to WHO medical and surgical recommendations. In all, 274 patients were diagnosed and treated, 57.7% of them children younger than 15 years. Ulcerative lesions (189, 69%) and WHO category II lesions (144, 52.5%) predominated. All patients received dual antibiotic therapy and 43.4% (119) underwent surgery as well. Category III lesions and multifocal lesions required more surgery, whereas most category I lesions healed under medical treatment. The overall rate of healing was 92%: 53.3% for patients who received only antibiotic therapy and 38.7% for those who also had surgery. The median healing time was 13 weeks and ranged from 4 to 56 weeks. In the CDTUB of Allada, between 2010 and 2014, most patients were treated with antibiotic therapy alone, but a significant number still received surgery.


Assuntos
Antibacterianos/uso terapêutico , Úlcera de Buruli/tratamento farmacológico , Úlcera de Buruli/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Benin , Criança , Pré-Escolar , Terapia Combinada , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Tempo , Adulto Jovem
2.
Bull Soc Pathol Exot ; 112(4): 190-194, 2019.
Artigo em Francês | MEDLINE | ID: mdl-32003196

RESUMO

Hookworm-related cutaneous larva migrans is caused by the subcutaneous migration of hookworm larvae. The characteristic sign is a serpiginous cutaneous track. Folliculitis is an uncommon clinical manifestation. We report a case of hookworm-related folliculitis in a woman performing skin bleaching. A 33-year-old woman presented with a widespread cutaneous eruption made of erythematous and itchy follicular papulo-nodules, with erythematous serpiginous tracks, about 5-10cm long and numerous streaks of scratching, located on the limbs, buttocks and trunk. The cutaneous lesions occurred two days after contact with the floor of a warehouse contamined by faeces of cats. The lesions have been evolving for a week and have been treated with antibiotics without success. Clinical examination found cutaneous atrophy, purple stretch marks and hyperpigmentation of dorsal parts of fingers joints. The patient reported having been using bleaching cosmetics containing topical steroids and hydroquinone for twelve years. She was cured within 4 weeks with oral albendazole 400mg per day during 7 consecutive days.


La folliculite ankylostomienne est une forme folliculaire de larva migrans cutanée ankylostomienne rarement observée. Nous en rapportons un cas chez une patiente de 33 ans, se dépigmentant depuis 12 ans. Elle a consulté pour une éruption évoluant depuis une semaine, diffuse, très prurigineuse, apparue deux jours après le contact avec le sol d'un entrepôt souillé par des déjections de chats. L'examen physique retrouvait de nombreuses lésions de folliculites, érythémateuses coexistant avec des cordons serpigineux de dermatite rampante sur les zones d'extension des membres, le dos, les fesses et l'abdomen, typiques de folliculite ankylostomienne. Un traitement à base d'albendazole 400 mg par jour pendant 7 jours a permis d'obtenir la guérison.


Assuntos
Ancylostomatoidea , Foliculite/parasitologia , Larva Migrans/diagnóstico , Preparações Clareadoras de Pele , Adulto , Albendazol/uso terapêutico , Animais , Anti-Helmínticos , Benin , Gatos , Fezes/parasitologia , Feminino , Humanos , Larva Migrans/tratamento farmacológico , Larva Migrans/etiologia
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