RESUMO
INTRODUCTION: Herein, we described cases of children under 16 years old suspected to be infected with Monkeypox virus (MKPV) and diagnosed with chickenpox in public hospitals of Marseille, south of France. MATERIAL AND METHODS: We conducted a retrospective study from March 23rd, 2022 to October 20th, 2022 in our institution of results of MKPV DNA and varicella-zoster virus (VZV) DNA detection by PCR performed on cutaneous lesions swabs collected from children <16 years old. RESULTS: None of the cutaneous swabs collected from 14 children were positive for MKPV DNA. In contrast, 30/168 (17 %) cutaneous swabs collected from children were positive for VZV DNA. Of these 30 VZV-positive children, 7 had been suspected of MKPV infection because of their atypical rash, due to the location of the lesions and the chronology of their appearance. DISCUSSION: As in our cohort, pediatric cases of the 2022 Monkeypox outbreak in non-endemic developed countries have been very rare. This variant of MKPV does not normally spread easily and requires very close physical contact between an infected person (skin lesions, bodily fluids or respiratory droplets) and another person to be transmitted. It will nevertheless be a question of remaining vigilant as not to ignore the possibility of close contact or sexual transmission of Monkeypox in a child, or the possibility of a new and more contagious variant. CONCLUSION: It is difficult to differentiate Monkeypox infection from other infections associated with rashes, it is important to remember that viruses change as well as their forms of presentation.
Assuntos
Varicela , Exantema , Mpox , Criança , Humanos , Adolescente , Varicela/epidemiologia , Mpox/diagnóstico , Mpox/epidemiologia , Estudos Retrospectivos , Herpesvirus Humano 3/genética , Surtos de Doenças , Monkeypox virus/genética , Exantema/diagnóstico , DNAAssuntos
Infecções por Vírus de DNA/urina , Transplante de Rim , Mimiviridae/isolamento & purificação , Transplantados , Urina/virologia , Acanthamoeba/virologia , Adulto , Infecções por Vírus de DNA/virologia , DNA Viral , Genoma Viral , Humanos , Transplante de Rim/efeitos adversos , Masculino , Microscopia Eletrônica , Mimiviridae/genética , Mimiviridae/ultraestruturaRESUMO
'Massilibacteroïdes vaginae' sp. nov. strain MV12T is the type strain of 'Massilibacteroïdes' gen. nov., a new genus within the family of Porphyromonadaceae. This strain was isolated in Marseille from a patient with vaginosis. 'Massilibacteroïdes vaginae' is a Gram-negative, aero-anaerobic bipolar bacillus. Here we describe the phenotypic characteristics and complete genome sequence of this bacterium. The EMBL accession number is FXDJ00000000 (FXDJ01000001-FXDJ01000009), and its genome consists of nine scaffolds. The strain was deposited in two culture collections under the numbers CSUR P1477 and DSM 100704.
Assuntos
Hepacivirus/isolamento & purificação , Hepatite C/virologia , Adulto , Idoso , Substituição de Aminoácidos , Feminino , França/epidemiologia , Técnicas de Genotipagem , Hepacivirus/classificação , Hepacivirus/enzimologia , Hepacivirus/genética , Hepatite C/epidemiologia , Hepatite C Crônica/epidemiologia , Hepatite C Crônica/virologia , Humanos , Masculino , Pessoa de Meia-Idade , Filogenia , RNA Viral/sangueRESUMO
Human parvovirus B19 occurs worldwide and causes mild or asymptomatic disease in the form of cyclic local epidemics usually occurring in late winter and early summer. In 2012, a dramatic increase in cases was observed in the Public hospitals system of Marseille, with a total of 53 cases reported. Here, we describe the characteristics of this outbreak and compare it with the local epidemiology of B19V infections observed during the 2002-2011 period.