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1.
BJOG ; 126 Suppl 3: 19-25, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30897283

RESUMO

OBJECTIVE: To investigate the burden and health service events surrounding severe maternal outcomes (SMO) related to life-threatening postpartum haemorrhage (PPH) in Nigerian public tertiary hospitals. DESIGN: Secondary analysis of a nationwide cross-sectional study. SETTING: Forty-two tertiary hospitals. POPULATION: Women admitted for pregnancy, childbirth or puerperal complications. METHODS: All cases of SMO [maternal near miss (MNM) or maternal death (MD)] due to PPH were prospectively identified using WHO criteria over a 1-year period. MAIN OUTCOME MEASURES: Incidence of SMO, health service events, case fatality rate (CFR) and mortality index (MI: % of death/SMO). RESULTS: Postpartum haemorrhage occurred in 2087 (2.2%) of the 94 835 deliveries recorded during the study period. A total of 354 (0.3%) women had an SMO (103 MD; 251 MNM). It was the most frequent obstetric haemorrhagic complication across hospitals. PPH had the highest maternal mortality ratio (112/100 000 live births) and the recorded MI (29.1%) and CFR (4.9%) were second only to that of ruptured uterus. About 83% of women with SMO were admitted in a critical condition with over 50% being referred. MD was more likely when PPH led to neurological (80.8%), renal (73.5%) or respiratory (58.7%) organ dysfunction. Although the timing of life-saving interventions was not statistically different between the cases of MD and MNM, close to one-quarter of women who died received critical intervention at least 4 hours after diagnosis of life-threatening PPH. CONCLUSIONS: Postpartum haemorrhage was a significant contributor to obstetric haemorrhage and SMO in Nigerian hospitals. Emergency obstetric services should be enhanced at the lower levels of healthcare delivery to reduce avoidable deaths from PPH. FUNDING: The original research that generated the data for this secondary analysis, and the publication of this secondary analysis, was funded by the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research Development and Research Training in Human Reproduction (HRP), a cosponsored programme executed by the World Health Organization. We have no other funding issue to declare for our study. TWEETABLE ABSTRACT: One hundred and three maternal deaths and 251 near-misses resulted from PPH in 42 Nigerian tertiary facilities in 1 year.


Assuntos
Morte Materna/estatística & dados numéricos , Near Miss/estatística & dados numéricos , Hemorragia Pós-Parto/mortalidade , Adulto , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Incidência , Nascido Vivo/epidemiologia , Morte Materna/etiologia , Mortalidade Materna , Nigéria/epidemiologia , Gravidez , Cuidado Pré-Natal/estatística & dados numéricos , Estudos Prospectivos , Centros de Atenção Terciária
2.
BJOG ; 123(6): 928-38, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-25974281

RESUMO

OBJECTIVE: To investigate the burden and causes of life-threatening maternal complications and the quality of emergency obstetric care in Nigerian public tertiary hospitals. DESIGN: Nationwide cross-sectional study. SETTING: Forty-two tertiary hospitals. POPULATION: Women admitted for pregnancy, childbirth and puerperal complications. METHODS: All cases of severe maternal outcome (SMO: maternal near-miss or maternal death) were prospectively identified using the WHO criteria over a 1-year period. MAIN OUTCOME MEASURES: Incidence and causes of SMO, health service events, case fatality rate, and mortality index (% of maternal death/SMO). RESULTS: Participating hospitals recorded 91 724 live births and 5910 stillbirths. A total of 2449 women had an SMO, including 1451 near-misses and 998 maternal deaths (2.7, 1.6 and 1.1% of live births, respectively). The majority (91.8%) of SMO cases were admitted in critical condition. Leading causes of SMO were pre-eclampsia/eclampsia (23.4%) and postpartum haemorrhage (14.4%). The overall mortality index for life-threatening conditions was 40.8%. For all SMOs, the median time between diagnosis and critical intervention was 60 minutes (IQR: 21-215 minutes) but in 21.9% of cases, it was over 4 hours. Late presentation (35.3%), lack of health insurance (17.5%) and non-availability of blood/blood products (12.7%) were the most frequent problems associated with deficiencies in care. CONCLUSIONS: Improving the chances of maternal survival would not only require timely application of life-saving interventions but also their safe, efficient and equitable use. Maternal mortality reduction strategies in Nigeria should address the deficiencies identified in tertiary hospital care and prioritise the prevention of severe complications at lower levels of care. TWEETABLE ABSTRACT: Of 998 maternal deaths and 1451 near-misses reported in a network of 42 Nigerian tertiary hospitals in 1 year.


Assuntos
Países em Desenvolvimento/estatística & dados numéricos , Hospitais Públicos/estatística & dados numéricos , Near Miss/estatística & dados numéricos , Complicações na Gravidez/mortalidade , Centros de Atenção Terciária/estatística & dados numéricos , Bancos de Sangue/provisão & distribuição , Transfusão de Sangue/estatística & dados numéricos , Causas de Morte , Estudos Transversais , Eclampsia/epidemiologia , Feminino , Hospitais Públicos/normas , Humanos , Incidência , Mortalidade Materna , Pessoas sem Cobertura de Seguro de Saúde/estatística & dados numéricos , Nigéria/epidemiologia , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Hemorragia Pós-Parto/epidemiologia , Pré-Eclâmpsia/epidemiologia , Gravidez , Complicações na Gravidez/epidemiologia , Estudos Prospectivos , Centros de Atenção Terciária/normas , Tempo para o Tratamento/estatística & dados numéricos
3.
Niger J Clin Pract ; 17(3): 287-91, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24714004

RESUMO

OBJECTIVES: To compare the effectiveness of two dosing regimens of vaginal misoprostol for cervical ripening and induction of labour. MATERIALS AND METHODS: Pregnant women with singleton low risk pregnancy at term scheduled for elective induction of labour were randomized to receive either 25 µg or 50 µg of vaginal misoprostol for pre-labour cervical ripening. All the patients received antenatal care and delivered at the University College Hospital (UCH) from January 1 st to May 31 st 2006. A total of 128 patients were randomized; 65 patients received 25 µg and 63 patients received 50 µg of vaginal misoprostol. RESULTS: Significantly higher number of patients in the 50 µg group progressed to active labour as compared with the 25 µg group (95.2% versus 84.6%, P < 0.05). The need for oxytocin augmentation of labour was higher among the 25 µg as compared with 50 µg (39.7% versus 16.4%, P = 0.007). There was higher proportion of patients in the 50 µg group delivering vaginally within 24 hours as compared with the 25 µg group (98.2% versus 90.0%, P = 0.063). However, the mean interval between the first dose of misoprostol and vaginal delivery was not statistically different in the two groups (754 ± 362 minutes and 885 ± 582 minutes, P = 0.152). The incidence of caesarean section was similar in the two groups (7.7% versus 11%, P = 0.580). Labour complications, such as precipitate labour, tachysystole and abnormal fetal heart rate patterns were greater in the 50 µg group. CONCLUSION: Twenty-five microgram of misoprostol appears to be as effective as 50 µg for pre-induction cervical ripening and labour induction. Though 50 µg of vaginal misoprostol resulted in relatively faster delivery and less need for oxytocin augmentation, it was associated with more labour complications as compared with 25 µg of misoprostol.


Assuntos
Maturidade Cervical/efeitos dos fármacos , Trabalho de Parto Induzido/métodos , Misoprostol/administração & dosagem , Ocitócicos/administração & dosagem , Maturidade Cervical/fisiologia , Relação Dose-Resposta a Droga , Feminino , Humanos , Trabalho de Parto Induzido/economia , Nigéria , Gravidez , Resultado da Gravidez
4.
Afr J Med Med Sci ; 43(4): 327-32, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26234120

RESUMO

BACKGROUND: Unsafe abortion is one of the causes of maternal morbidity and mortality globally and it is still a burden in Nigeria. Restriction laws have been blamed for the recurrent vulnerability of women including female adolescents to unsafe abortions. METHODS: A cross-sectional, semi-structured, self-administered questionnaire was administered to 407 first year female undergraduates in the three female halls of residence of the University of Ibadan, Nigeria in February 2012 to determine their attitudes to abortion laws and the social acceptance of abortion laws in Nigeria. RESULTS: A vast majority (96.1%) knew what an abortion was and barely half were aware of the grounds in which it may be legal. Only 84 (20.6%) of the respondents knew that there were 2 abortion laws in operation in Nigeria. One hundred and thirteen (27.8%) wanted the current abortion law to be reformed and thirteen (3.2%) admitted that they had had an abortion in the past. More than half of them, 212 (52.1%) would support an abortion if pregnancy followed rape/ incest and 201(49.4%) if there was fetal abnormality. Religious reasons influenced the social opinions on abortion laws in most of the students (73%). CONCLUSION: The study showed some awareness towards abortion law reforms and we advocate that sexually active young individuals should be encouraged to adopt effective dual protection against unwanted pregnancy and STIs. Efforts should also be made at imparting reproductive health education to youths, especially girls.


Assuntos
Aborto Induzido/legislação & jurisprudência , Aborto Induzido/psicologia , Conhecimentos, Atitudes e Prática em Saúde , Estudantes/psicologia , Adolescente , Adulto , Estudos Transversais , Feminino , Humanos , Nigéria/epidemiologia , Estudantes/estatística & dados numéricos , Universidades , Adulto Jovem
5.
Ann Ib Postgrad Med ; 11(1): 22-8, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25161419

RESUMO

BACKGROUND: Antenatal care is an important health service which detects and sometimes reduces the risk of complications among pregnant women. The quality of care is likely to influence effective utilization and compliance with interventions. OBJECTIVES: This study evaluated clients' perception of antenatal care quality at the University College Hospital (UCH), Ibadan and determined levels of client satisfaction. METHODS: Women presenting for antenatal care at the study centre were interviewed in a cross-sectional design using a structured questionnaire. Items in the questionnaire included sociodemographic and obstetric variables, assessment of quality of amenities, waiting time and level of satisfaction. Data analysis was done using frequency tables, Chi-square cross tabulations and logistic regression. The p-value was set at P<0.05. RESULTS: There were 239 participants; 74% percent of the women were aged 25-34 years; majority of the respondents (86%) had tertiary education while 49.4% were skilled workers or professionals. In 57.7% of women, the gestational age was between 13 and 27 weeks while 66.1% were Para 1-4. Amenities and water supply were regarded as unsatisfactory in 60.7% and 61.9% respectively. The clinic services were regarded as good in 81.1% of respondents; the only significant association with patient satisfaction was the desire to register in the same facility in the next pregnancy. CONCLUSION: There is a high overall level of satisfaction with antenatal services among pregnant women in UCH. Policy makers and health providers should however address improvement of amenities, reduction of waiting time and ensure that health interventions are available for all clients.

6.
J Biosoc Sci ; 41(4): 493-503, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19302728

RESUMO

This was a cross-sectional study carried out on 462 pregnant women attending antenatal care in Ibadan, Nigeria. The study's aims were to assess the level of participation of Nigerian men in pregnancy and birth, the attitude of the women and likely targets for improved care delivery. Three hundred and forty-nine women (75.5%) were aware that husbands could participate in childbirth. Most women did not think it was their husbands' place to attend antenatal clinic (48.3%) or counselling sessions (56.7%). Nearly all husbands (97.4%) encouraged their wives to attend antenatal clinic - paying antenatal service bills (96.5%), paying for transport to the clinic (94.6%) and reminding them of their clinic visits (83.3%). Three hundred and thirty-five husbands (72.5%) accompanied their wives to the hospital for their last delivery, while 63.9% were present at last delivery. More-educated women were less likely to be accompanied to the antenatal clinic, while more-educated men were likely to accompany their wives. Yoruba husbands were less likely to accompany their wives, but Yoruba wives with non-Yoruba husbands were 12 times more likely to be accompanied. Women in the rural centre were less likely to receive help with household chores from their husbands during pregnancy, while educated women were more likely to benefit from this. Monogamous unions and increasing level of husbands' education were associated with spousal presence at delivery. It appears that male participation is satisfactory in some aspects, but increased attendance at antenatal services and delivery would be desirable.


Assuntos
Atitude Frente a Saúde , Parto Obstétrico , Cuidado Pré-Natal , Cônjuges , Adulto , Atitude Frente a Saúde/etnologia , Estudos Transversais , Feminino , Comportamento de Ajuda , Humanos , Modelos Logísticos , Masculino , Nigéria , Gravidez , Fatores Socioeconômicos , Cônjuges/etnologia
7.
Ann Ib Postgrad Med ; 7(1): 21-5, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25161458

RESUMO

OBJECTIVES: To determine the frequency of retained placenta at the University College Hospital Ibadan (UCH). and to describe the socio-demographic characteristics of the patients and examine the risk factors predisposing to retained placenta. METHODS: This is a descriptive study covering a period of 5 years from January 1(st) 2002 to December 31(st) 2006. During the study period, 4980 deliveries took place at the University College Hospital, Ibadan and 106 cases of retained placenta were managed making the incidence 2.13 per cent of all births. RESULTS: During the five year period, there were 106 patients with retained placenta; of these, 90 (84.9%) case notes were available for analysis. The mean age was 29.37 ± 4.99 years. First and second Para accounted for 52 per cent of the patients. Majority of the patient were unbooked for antenatal care in UCH with booked patients accounting for 27.8 per cent of the cases. The mean gestational age at delivery was 34.29 ± 6.02. Three patients presented to the hospital in shock of which 2 died on account of severe haemorrhagic shock. Fifty-eight patients (64.8%) presented with anaemia (packed cell volume less than 30 per cent) and 35 patients (38.8%) had blood transfusion ranging between 1-4 pints. 1 patient required hysterectomy on account of morbidly adherent placenta. Eleven patients (12.2%) had placenta retention in the past, 28 patients (31%) had a previous dilatation and curettage, 14 patients (15.5%) had previous caesarean sections and 47 patients (41.3%) had no known predisposing factors. CONCLUSION: Retained placenta still remains a potentially life threatening condition in the tropics due to the associated haemorrhage, and other complications related to its removal. The incidence and severity may be decreased by health education, women empowerment and the provision of facilities for essential obstetric services by high skilled health care providers in ensuring a properly conducted delivery with active management of the third stage of labour.

8.
Afr J Reprod Health ; 12(2): 141-52, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-20695049

RESUMO

The prevalence of malaria parasitemia at booking was studied in 1,848 pregnant women in a secondary hospital in Ibadan, Nigeria. Main outcome variables were patent parasitemia and fever. 8.4% hadpatent malaria parasitaemia. Most clients (89%) with parasitemia were asymptomatic. Febrile subjects booked at an earlier gestational age [22.7 versus 24.2 weeks] than afebrile patients (p = 0.0052). Anemia was more prevalent among patients with patent parasitemia than those without (58.1% versus 22.6%, p < 0.0001). Malaria parasitaemia was higher among nulliparous women than other parity groups (p < 0.0001). Symptomatic malaria was associated with early booking for antenatal care and malaria parasitemia was a significant determinant of anemia. The prevalence of malaria parasitaemia in this study is much lower than in previous reports.


Assuntos
Anemia/epidemiologia , Malária/epidemiologia , Parasitemia/epidemiologia , Complicações Parasitárias na Gravidez/epidemiologia , Adulto , Estudos Transversais , Feminino , Idade Gestacional , Hospitais Religiosos , Humanos , Incidência , Malária/diagnóstico , Nigéria/epidemiologia , Parasitemia/diagnóstico , Gravidez , Cuidado Pré-Natal , Prevalência
9.
J Obstet Gynaecol ; 27(8): 802-5, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18097898

RESUMO

In Nigeria, breast-feeding has been shown to be very closely related to infant survival. Prolonged and adequate breast-feeding is critical to most infants' nutritional health and growth. This study aims to determine the influence of family support on the duration of exclusive and total breast-feeding of infants of antenatal patients. This cross-sectional study was conducted between 1 September and 30 December 2005. The tool was a structured questionnaire. The main outcome variables were the duration of breast-feeding; both total and exclusive explanatory variables were mainly related to support obtained during breast-feeding from husband and older female relations. Husbands support significantly increased the total duration of breast-feeding by a mean of 1.69 months (95% CI 0.88, 2.51), however, exclusive breast-feeding was not significantly affected by the husband's support (OR 0.94; 95% CI 0.63, 1.39). Female support had a significant influence on both the total duration of breast-feeding which is increased by a mean of 1.08 months (95% CI 0.14, 2.02), and the adequate conduct of exclusive breast-feeding (OR 1.83; 95% CI 1.17, 2.86). The cultural practice of having additional female support in the postpartum period has been shown by this study to be beneficial. Therefore, this cultural practice should be encouraged and catalogued as a beneficial cultural practice. This practice is also cheap and sustainable.


Assuntos
Aleitamento Materno/psicologia , Apoio Social , Adulto , Cuidadores , Estudos Transversais , Feminino , Humanos , Masculino , Nigéria , Período Pós-Parto , Gravidez , Cuidado Pré-Natal , Cônjuges/psicologia , Inquéritos e Questionários , Fatores de Tempo
10.
J Obstet Gynaecol ; 26(4): 329-31, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16753683

RESUMO

Pain perception as perceived by the parturient is determined by physical and psychological factors. The interplay of these factors is important to the healthcare professional who will be managing these women in labour. We therefore set out to assess the influence of educational attainment as a proxy for westernisation on pain perception by parturients. This was a cross-sectional study conducted among 765 parturients using a questionnaire with the Box Numerical Scale to assess pain score within 48 h of delivery. We studied women in labour at the University College Hospital Ibadan Nigeria from August 2003 to July 2004. A total of 1,000 consecutive parturients were enrolled into the study but 765 were included in the analysis after excluding women requiring caesarean section. Multiple linear regression with robust estimation of the Standard Error of the Mean (SEM) was utilised. The main outcome studied was the pain score obtained within 48 h of delivery using the Box Numerical Scale (BNS). The pain scores were highest among ethnic groups other than the predominant ethnic group (Yoruba) 9.13 (95% CI 8.13 - 9.33), it was lowest among those with no formal education. Multivariate analysis revealed educational attainment as a significant predictor of BNS. An interaction between age and educational attainment; only women between the ages of 25 - 30 had lower mean pain scores when educated compared with those without formal education -3.56 (95% CI -4.28, -2.87). In conclusion, findings in this study support the hypothesis that westernisation through education tends to increase perception of pain by parturients in this environment.


Assuntos
Escolaridade , Dor do Parto , Limiar da Dor , Adulto , Estudos Transversais , Feminino , Hospitais Universitários , Humanos , Nigéria , Gravidez
11.
Trop Doct ; 35(3): 171-2, 2005 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16105348

RESUMO

Two hundred and fifty patients with uterine fibroids were reviewed to compare operative outcomes and blood loss.


Assuntos
Perda Sanguínea Cirúrgica , Histerectomia/métodos , Leiomioma/cirurgia , Neoplasias Uterinas/cirurgia , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Resultado do Tratamento
12.
Afr J Reprod Health ; 9(1): 123-7, 2005 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16104661

RESUMO

Fourteen cases of abdominal pregnancy managed at the University College Hospital, Ibadan, Nigeria, over a ten-year period (January 1994 to December 2003) were reviewed. The incidence ratio of abdominal pregnancy was one in 654 deliveries. It accounted for 4.3% of ectopic pregnancies. Age range was 20 to 43 years; 63.4% of the patients were unemployed and 50% were nullipara. Pre-operative diagnosis was possible only in half of the cases. Only two patients with advanced pregnancies and live fetuses (14.3%) were allowed to have conservative management while the others had immediate laparotomy. Live birth rate was 7.1%, but overall fetal survival rate was 0%. Fetal malformations were common, with talipes equinovarus and jaw abnormalities occurring in 49.2% and 14.3% respectively. Twelve patients (85.7%) who had complete removal of the placenta, though lost more blood, had better outcome than those with placenta left in-situ. The case fatality rate was 7.1%.


Assuntos
Resultado da Gravidez , Gravidez Abdominal/diagnóstico por imagem , Gravidez Abdominal/cirurgia , Gravidez de Alto Risco , Adulto , Países em Desenvolvimento , Feminino , Hospitais Universitários , Humanos , Laparotomia/métodos , Pessoa de Meia-Idade , Nigéria , Gravidez , Gravidez Abdominal/mortalidade , Cuidado Pré-Natal/métodos , Sistema de Registros , Estudos Retrospectivos , Medição de Risco , Taxa de Sobrevida , Resultado do Tratamento , Ultrassonografia Pré-Natal
13.
J Obstet Gynaecol ; 25(2): 128-30, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15814389

RESUMO

This cross-sectional study of one thousand parturients aims to evaluate the factors, which are associated with pain perception in labour and to identify women who will benefit most from analgesia in labour. The instrument applied was a structured questionnaire incorporating the Box numerical scale (BNS) for pain assessment. Patients who delivered by elective or emergency caesarean section and women who did not give informed consent were excluded from the study. Spearman's and Pearson's correlational analyses were applied. Pain scores showed significant correlation with age (r=- 0.087, p<0.01), parity (r=- 0.226, p<0.01), gestational age at delivery (r=- 0.074, p<0.05), onset of labour (rho=0.195, p<0.01), mode of delivery (rho=0.160, p<0.01), booking status (rho=- 0.070, p<0.05) and educational status (rho=0.182, p<0.01). Certain groups of patients would benefit from obstetric analgesia. These patients include, nulliparous patients, young patients, patients who have had labour induced, those with preterm deliveries and those with an assisted vaginal delivery especially if they are well educated.


Assuntos
Atitude Frente a Saúde , Dor do Parto/psicologia , Trabalho de Parto , Adulto , Analgesia Obstétrica , Estudos Transversais , Feminino , Hospitais Universitários , Humanos , Dor do Parto/tratamento farmacológico , Dor do Parto/epidemiologia , Dor do Parto/etiologia , Nigéria/epidemiologia , Medição da Dor , Paridade , Gravidez
14.
J Obstet Gynaecol ; 25(2): 134-9, 2005 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15814391

RESUMO

The object of this study was to compare the effectiveness of the intravaginal Misoprostol and transcervical Foley catheters as pre-induction cervical ripening agents, to estimate the proportion of patients achieving vaginal delivery and to compare the complications of labour and foetal outcome between the two groups. The study was a prospective, randomised study of pregnant women, with singleton pregnancies who presented for antenatal care and delivery at the University College Hospital (UCH), Ibadan, Nigeria. Ninety-nine patients were invited to participate and ninety-six (96) agreed. No patient withdrew from the study. The patients were assigned by means of computer-generated random numbers to receive transcervical Foley catheters (Size 16F, with 30 ml balloon capacity) or 50 microg intravaginal Misoprostol (Cytotec tablet, Searle & Co., Chicago). Fifty (50) patients received intravaginal Misoprostol and Forty-six (46) received Transcervical Foley catheters. The proportions of nulliparous, primiparous and multiparous patients were 52, 20 and 28% in the misoprostol group and 43.5, 26.1 and 30.4%, respectively, in the Foley catheter group. The time to achieve a favourable cervical status was significantly shorter in the Misoprostol group, with 98.0% of the subjects attaining Bishop score > or = 6 within 6-12 hours of insertion of the study agent, in contrast to 69.0% of the subjects in the Foley catheters group (P<0.001). Thirteen (26.6%) and three (6.5%) patients in the Misoprostol and Foley catheters groups, respectively, went into labour while undergoing cervical ripening and all had uneventful vaginal deliveries (P<0.05). The induction-delivery interval did not differ significantly between the groups. The incidence of caesarean delivery was 6.0% in the Misoprostol group compared with 2.2% in the Foley catheter group (P=0.62). Instrumental vaginal delivery rates were similar in both groups. Overall, the mode of delivery did not differ significantly between the groups. The number of neonates with 1-minute Apgar score <7 did not differ significantly in both groups and no neonate had 5-minute Apgar score <7. Meconium stained liquor was noticed in 5 (Misoprostol) vs 2 (Foley catheters) patients in labour. None of the neonates had any features suggestive of meconium aspiration. Labour complications were mainly precipitate labour {2 (Misoprostol) vs 1 (Foley catheters) } and 1 patient with transient tachysystole (> or =6 contractions in 10 minutes for two consecutive 10-minute periods) in the Misoprostol group. Hyperstimulation was not noticed in any of the patients in either arm of the study groups. Intravaginal Misoprostol is as effective a pre-induction cervical ripening agent as transcervical Foley catheters, with added advantages of shorter duration of cervical ripening, reduced oxytocin requirement for induction of labour and greater acceptability to patients. The incidence of caesarean sections, other labour complications and the foetal outcome were similar with both methods.


Assuntos
Cateterismo , Maturidade Cervical , Trabalho de Parto Induzido , Misoprostol/administração & dosagem , Ocitócicos/administração & dosagem , Administração Intravaginal , Adulto , Feminino , Humanos , Nigéria , Complicações do Trabalho de Parto , Gravidez , Resultado da Gravidez , Estudos Prospectivos , Resultado do Tratamento
15.
Afr J Med Med Sci ; 34(4): 377-82, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16752669

RESUMO

The study compares the changes in the cervical factors in pre-induction cervical ripening with both transcervical Foley catheter and Intravaginal Misoprostol. This was a randomised prospective study of pregnant women, with singleton gestations who presented for antenatal care and delivery at a tertiary health institution in the South-western Nigeria between 1st March 2003 and 31st March 2004. One hundred and two (102) patients received 50microg intravaginal Misoprostol and Ninety-six (96) received size 16F Transcervical Foley catheters. Both groups were similar at the baseline. Misoprostol group showed greater improvement in the final cervical length score, with 38.4% and 58.6% scoring 2 and 3 respectively, in contrast with the Foley catheter group where 77.7% had final score of 1, with only 16% scoring 2 and none scored 3 (P = 0.00). Ninety-one percent of the patients in the misoprostol group achieved the maximum cervical consistency score of 2, contrasting with the 31.9% in the Foley Catheter group (P = 0.00). 64.9% of the patients in the Foley catheter group did not achieve appreciable change in cervical consistency. Our findings indicate that intravaginal misoprostol was more effective in improving the scores of cervical length and consistency, while transcervical Foley catheter was better at improving the cervical os dilatation score at pre-induction cervical ripening. The clinical implication is that, patients for pre-induction cervical ripening can be selected for either of these ripening agents based on which cervical factors require improvement in scores


Assuntos
Abortivos não Esteroides/administração & dosagem , Cateterismo , Maturidade Cervical , Trabalho de Parto Induzido/métodos , Misoprostol/administração & dosagem , Ocitócicos/administração & dosagem , Administração Intravaginal , Adulto , Maturidade Cervical/efeitos dos fármacos , Feminino , Humanos , Trabalho de Parto Induzido/instrumentação , Gravidez , Estudos Prospectivos , Instrumentos Cirúrgicos , Fatores de Tempo , Resultado do Tratamento
16.
Afr J Med Med Sci ; 33(2): 99-103, 2004 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15565924

RESUMO

The detection and clinical management of hypertension in pregnant women are complicated by the concern for fetal development and survival as well as for the health of the mother. Preeclampsia describes a common syndrome that occurs in the second half of pregnancy and often manifesting with hypertension and proteinuria. It occurs in up to 10% of all pregnancies. The factors that initiate preeclampsia are unknown and still a subject of intense clinical research by both Obstetricians and Physicians. The blue print for the development of preeclampsia is probably laid down early in pregnancy, and delivery of the fetus and placenta remains the only effective treatment. Severaclinical, biophysical and biochemical tests have been reported in the world literature to predict the development of preeclampsia. Also, numerous reports have described the predictive value of every possible substance that can be measured in maternal blood or urine. However, the presence of microalbuminuria is an important clinical finding in pregnant women. Indeed, urinary albumin excretion when used as a single test has shown that albumin excretion was higher at booking in those that later developed hypertensive disorders of pregnancy than those that did not have the condition. It had a higher sensitivity and poor predictive value. In conclusion, the factors that are responsible for hypertensive disorders of pregnancy remain unknown and treatment is still difficult. The search for an ideal predictive test or tests should therefore be a continuous exercise.


Assuntos
Hipertensão Induzida pela Gravidez/diagnóstico , Hipertensão Induzida pela Gravidez/etiologia , Feminino , Humanos , Hipertensão Induzida pela Gravidez/fisiopatologia , Hipertensão Induzida pela Gravidez/terapia , Valor Preditivo dos Testes , Gravidez
17.
J Obstet Gynaecol ; 24(3): 294-7, 2004 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-15203632

RESUMO

Ovarian cancer has the highest case fatality rate among gynaecological cancers worldwide because of lack of effective screening methods and non-specific early warning symptoms with late presentation. A reinvigorated study is necessary in the developing countries because of a projected increase in its incidence. The decreasing fertility rate and increasing use of ovulation induction drugs are some of the reasons. The Ovarian Cancer Service of the Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Oyo State, Nigeria commenced the first longitudinal study of this malignancy from 1 December 1998 in order to establish a regional management and research centre. It is a questionnaire survey detailing the demography, clinical and staging laparotomy findings and histology of all confirmed cases. Twenty-one staging laparotomy and histologically confirmed ovarian cancer cases were managed from 1 December 1998 to 31 July 2002, about 1.5% of the 1387 gynaecological admissions. It is the third most common of the gynaecological cancers, representing 9.8% of the 214 cases. More than 60% of the patients were 50 years or younger. Only 19% were nulliparous, with 47.6% having had five or more deliveries. Only two patients (9.5%) had used the oral contraceptive pill, for a maximum period of 1 month. Only one patient (4.8%) had a positive family history of cancer. Abdominal swelling was the most common presenting symptom. Eighty-one per cent of the patients presented in Stages III and IV. Epithelial ovarian cancer constituted about 76.2% of the cases. Only 23.8% had adjuvant therapy, consisting of combination chemotherapy using cisplatin-based regimes. The case fatality rate 6 months after surgery was 76%. The ovarian cancer patients in this environment are younger and of higher parity than expected. The risk factors for this disease require further study.


Assuntos
Neoplasias Ovarianas/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Terapia Combinada , Feminino , Humanos , Incidência , Estudos Longitudinais , Pessoa de Meia-Idade , Nigéria/epidemiologia , Neoplasias Ovarianas/diagnóstico , Neoplasias Ovarianas/etiologia , Neoplasias Ovarianas/mortalidade , Neoplasias Ovarianas/terapia , Fatores Socioeconômicos
18.
J Obstet Gynaecol ; 24(1): 58-63, 2004 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-14675983

RESUMO

Violence against women is an important health and human rights issue. It carries with it both short- and long-term sequelae for women that can affect both their physical and psychological wellbeing. Every day obstetric providers treat patients who have been assaulted. Timely identification can interrupt the cycle of violence, prevent further injury and initiate the help-seeking process. The objectives of this study were to survey how often Nigerian obstetrician-gynaecologists see these patients in their practice and to describe the demographics and management of their most recent case so as to give an idea of the extent of the problem. This is especially important as abuse is grossly under-reported because the victims are afraid to report it because of male dominance in society and the fear of losing their homes. We used a self-administered questionnaire survey of 138 practising obstetricians and gynaecologists in Nigeria. Questions were asked about the yearly estimation of cases seen and how recently a case was seen. The type of abuse, risk factors and management of their most recent case was also documented. Most (98.6%) obstetricians surveyed had previously managed a case of violence. The mean estimate of abused women seen was 7.0 per year. Details of the last case managed were recollected by 91.3% of respondents. The majority (51.6%) of patients were pregnant. The assailant was the husband in 69.8% of cases and the most common factor for abuse was as a result of women requesting money for the family needs from their husbands. The most common type of abuse was physical (79.4%), with 34.9% of patients sustaining cuts. Treatment and counselling were the forms of management in most cases. The police were informed in 9.5% of cases and one obstetrician had to give evidence in court. Of the pregnant abused women, 73.8% had live births. Better job opportunities and female empowerment can reduce the risk of violence. Obstetricians should screen routinely for battery, provide education about violence, assess the danger, review safety plans and refer women appropriately. We cannot solve the problem alone, but sensitivity and commitment can begin to make a difference.


Assuntos
Mulheres Maltratadas/estatística & dados numéricos , Notificação de Abuso , Saúde da Mulher , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/etiologia , Adulto , Países em Desenvolvimento , Feminino , Ginecologia/normas , Ginecologia/tendências , Humanos , Incidência , Masculino , Nigéria/epidemiologia , Obstetrícia/normas , Obstetrícia/tendências , Gravidez , Prevenção Primária/organização & administração , Fatores de Risco , Inquéritos e Questionários , Violência/estatística & dados numéricos , Ferimentos e Lesões/terapia
19.
West Afr J Med ; 22(3): 222-4, 2003 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-14696945

RESUMO

UNLABELLED: The incidence of forceps delivery has reduced in Nigeria and in the world in general. Some Obstetricians have not been trained in its use and lack the skill. OBJECTIVE: To determine the outcome of forceps delivery at this centre. METHODOLOGY: A retrospective analysis of all forceps delivery done at this centre between the 1st of January 1997 and 31st December 2001, a 5-year period was done. RESULTS: The incidence of forceps delivery was 1.57% or 16 per 1000 births and they were all low cavity deliveries. Most of the patients (68.5%) were booked at this centre. The mean age was 28.21 +/- 4.79 years and most (64.4%) were nulliparious. The mean gestational age at delivery was 38.7 +/- 3.0 weeks. The most common indications were prolonged second stage of labour (58.9%), maternal distress (43.8%) and fetal distress (15.1%). There were multiple indications in some patients. The mean birth weight was 3.03 +/- 0.69 kgs and 90.4% were live births. The main maternal complications were maternal injuries (8.1%), primary post partum haemorrhage (5.5%), anaemia (5.5%) and retained products of conception (4.1%). Maternal deaths occurred in 2 eclamptics and birth asphyxia in 6.9% of babies. The perinatal mortality rate was 54.8 per 1000 births. There were no fetal injuries. CONCLUSION: Obstetrics forceps delivery is on the decline in Nigeria. It is an art that can safely and quickly deliver the fetus. It could be offered in the place of a caesarean section in some instances with a good outcome to both the mother and fetus in skilled hands. Obstetricians should be trained to use it more frequently.


Assuntos
Extração Obstétrica/estatística & dados numéricos , Resultado da Gravidez/epidemiologia , Adulto , Emergências , Extração Obstétrica/instrumentação , Feminino , Hospitais de Ensino/estatística & dados numéricos , Humanos , Incidência , Mortalidade Infantil , Recém-Nascido , Idade Materna , Nigéria/epidemiologia , Forceps Obstétrico , Paridade , Hemorragia Pós-Parto/epidemiologia , Gravidez , Transtornos Puerperais/epidemiologia , Estudos Retrospectivos
20.
West Afr J Med ; 22(3): 236-9, 2003 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-14696948

RESUMO

OBJECTIVES: To determine the incidence, predisposing factors, maternal and fetal outcome of uterine rupture patients at the University College Hospital (U. C. H.), Ibadan. MATERIALS AND METHODS: A 5-year retropective study of patients with uterine rupture in U. C. H., Ibadan between January 1996 - December, 2000 was done. RESULTS: Thirty five cases of uterine rupture out of a total delivery of 4531 were recorded over the 5-year period. An incidence of 7.75/1000 deliveries or 0.72% was obtained and the yearly trend showss it's on the increase. 85.7% of the patients were unbooked. Common modes of presentation were bleeding per vaginam and abdominal pain. Spontaneous cause of rupture predominates. The interval between diagnosis and surgery was greater than 7 hours in 75% of cases. Uterine repair with or without tubal ligation was commonly employed. Case fatality rate was high at 17.9%. Perinatal mortality was 92.5%. Other maternal morbidities include anaemia, puerperal and wound sepsis, vesico-vaginal fistula and prolonged hospital stay. CONCLUSION: All the indice at the present time are higher than they were 10 years ago. The incidence is still high and is on the increase. Attributable reasons include type I, II, III delays in health care service utilization associated with poor socioeconomic status of patients and lack of essential drugs and compatible blood in the hospitals.


Assuntos
Resultado da Gravidez/epidemiologia , Ruptura Uterina/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Feminino , Humanos , Incidência , Nigéria/epidemiologia , Paridade , Gravidez , Complicações na Gravidez/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Taxa de Sobrevida , Ruptura Uterina/diagnóstico , Ruptura Uterina/cirurgia
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