Occlusal adjustment of 3-unit tooth-supported fixed dental prostheses fabricated with complete-digital and -analog workflows: A crossover clinical trial.

AIM: This prospective crossover clinical trial aimed to compare the complete-digital and -analog workflows in terms of occlusal adjustment of 3-unit tooth-supported fixed dental prostheses, operator, and patient preferences. MATERIALS AND METHOD: This study included twelve patients receiving fourteen 3-unit posterior FDPs. 2 FDPs were made for each restoration site: one fabricated in complete-digital workflow comprising intraoral scan with static bite registration (Trios 3) and a monolithic zirconia FDP (test); the other fabricated in complete-analog workflow comprising conventional impression/face-bow transfer and a porcelain-fused-to-metal FDP (control). The FDPs (n=28) were intraorally/provisionally fixed, and quadrant-like intraoral scans were taken for every FDP before & after their occlusal adjustments. Pre- and post-adjustment scans of each FDP were then superimposed using best-fit alignment (GOM Inspect) to measure the volumetric occlusal adjustment amount (mm3) (3Matic) (Mann Whitney U, α=0.05). The patient and operator experience for digital and analog workflows were evaluated using visual analog scales (Wilcoxon test, α=0.05). RESULTS: Mean occlusal adjustments were 7.63 mm3 [±7.02] and 25.95 mm3 [±39.61] for test and control groups, respectively. The volumetric adjustment difference was clinically noticeable but not significant (P=0.12). The impression and digital workflow adjustment were perceived more favorably by both operator (P=0.003, P=0.046, respectively) and the patients (P=0.003, P=0.002, respectively). CONCLUSIONS: Within the limitations of this clinical study, the complete digital workflow with digital static bite-registration provided high occlusal accuracy for short-span tooth-supported FDPs. In addition, the patient and operator preferences significantly favored the digital workflow. CLINICAL SIGNIFICANCE: Complete-digital workflow employing intraoral scanning and model-free fabrication of monolithic-Zr short-span tooth-supported FDPs offers an effective treatment modality with sufficient occlusal accuracy. Therefore complete-digital workflow is a valid alternative for complete-analog workflow comprising conventional impression, face-bow transfer, and use of a semi-adjustable articulator.

Mechanical Failure of Endocrowns Manufactured with Different Ceramic Materials: An In Vitro Biomechanical Study.

PURPOSE: To evaluate the effect of different silica-based ceramic materials on the mechanical failure behavior of endocrowns used in the restoration of endodontically treated mandibular molar teeth. MATERIALS AND METHODS: Thirty-six intact mandibular molar teeth extracted because of a loss of periodontal support received root canal treatment. The teeth were prepared with a central cavity to support the endocrowns, replacing the occlusal surface with mesial-lingual-distal walls. Data acquisition of the prepared tooth surfaces was carried out digitally with a powder-free intraoral scanner. Restoration designs were completed on manufactured restorations from three silicate ceramics: alumina-silicate (control), zirconia-reinforced (Zr-R), and polymer-infiltrated (P-I). Following adhesive cementation, endocrowns were subjected to thermal aging, and then, each specimen was obliquely loaded to record the fracture strength and define the mechanical failure. For the failure definition, the fracture type characteristics were identified, and further analytic measurements were made on the fractured tooth and ceramic structure. RESULTS: Load-to-fracture failure did not differ significantly, and the calculated mean values were 1035.08 N, 1058.33 N, and 1025.00 N for control, Zr-R, and P-I groups, respectively; however, the stiffness of the restoration-tooth complex was significantly higher than that in both test groups. No statistically significant correlation was established in paired comparisons of the failure strength, restorative stiffness, and fractured tooth distance parameters. The failure mode for teeth restored with zirconia-reinforced glass ceramics was identified as non-restorable. The resin interface in the control and P-I groups presented similar adhesive failure behavior. CONCLUSION: Mechanical failure of endocrown restorations does not significantly differ for silica-based ceramics modified either with zirconia or polymer.

Numerical assessment of bone remodeling around conventionally and early loaded titanium and titanium-zirconium alloy dental implants.

The aim of this study was to investigate conventionally and early loaded titanium and titanium-zirconium alloy implants by three-dimensional finite element stress analysis. Three-dimensional model of a dental implant was created and a thread area was established as a region of interest in trabecular bone to study a localized part of the global model with a refined mesh. The peri-implant tissues around conventionally loaded (model 1) and early loaded (model 2) implants were implemented and were used to explore principal stresses, displacement values, and equivalent strains in the peri-implant region of titanium and titanium-zirconium implants under static load of 300 N with or without 30° inclination applied on top of the abutment surface. Under axial loading, principal stresses in both models were comparable for both implants and models. Under oblique loading, principal stresses around titanium-zirconium implants were slightly higher in both models. Comparable stress magnitudes were observed in both models. The displacement values and equivalent strain amplitudes around both implants and models were similar. Peri-implant bone around titanium and titanium-zirconium implants experiences similar stress magnitudes coupled with intraosseous implant displacement values under conventional loading and early loading simulations. Titanium-zirconium implants have biomechanical outcome comparable to conventional titanium implants under conventional loading and early loading.

A pilot study of joint stability at the zirconium or titanium abutment/titanium implant interface.

PURPOSE: To compare the interfaces of loaded and unloaded zirconium and titanium abutments with titanium implants using scanning electron microscopy (SEM). MATERIALS AND METHODS: Zirconium and titanium abutments (n = 5 per group; four test and one control) were torque-tightened into titanium implants secured into metal blocks, and computer-aided design/computer-assisted manufacture-based zirconium oxide copings were fabricated and cemented to the abutments with temporary resin-based cement. Specimens of each restoration were subjected to cyclic axial and lateral loading of 30 N at 2 Hz for 500,000 cycles using a servohydraulic test system; control specimens were left unloaded. Then, the abutment/implant assemblies were embedded in acrylic resin, sectioned longitudinally along the midline, and inspected under SEM with x-ray microanalysis. RESULTS: Loosening or fracture of the copings and implant components was not observed after dynamic loading in both groups. SEM and x-ray microanalysis revealed unexpected microleakage of acrylic resin at the interface. Acrylic resin in the implants tightened to the titanium abutments was limited to the cervical part, and the components displayed scratched and smashed regions, suggesting slight deformation of the implant neck. Microleakage and pooling of acrylic resin were observed approaching the screw joint in loaded implants tightened to zirconia abutments, and the amount of microleakage was greater than in the unloaded control specimens, which had a larger microgap than the titanium abutment/titanium implant interface. Loaded zirconia abutments were associated with wear, scratches, and, in one sample, chipping. CONCLUSIONS: Zirconium abutment/titanium implant interface may be susceptible to wear of the abutment coupled with deformation of the implant neck greater than that associated with the conventional titanium abutment/titanium implant interface under dynamic loading.

Effect of digitizing techniques on the fit of implant-retained crowns with different antirotational abutment features.

STATEMENT OF PROBLEM: The development of computer-aided design/computer-aided manufacturing technology has enabled the fabrication of implant-retained restorations. However, information on the marginal and axial accuracy of restorations fabricated by different digitizing techniques with different antirotational abutment features is not sufficient. PURPOSE: The purpose of this in vitro study was to evaluate the influence of digitizing techniques on the fit of implant-retained crowns with 2 antirotational features. MATERIAL AND METHODS: An experimental working cast housing a tissue-level dental implant was created. Resin-retained abutments with different antirotational features were connected to the implant. Optical impressions of 2 abutment types were obtained separately with 1 chairside and 2 laboratory approaches. Alumina silicate restorations were milled from chairside optical impressions, and ceramic oxide cores were milled from laboratory optical impressions. Restoration fit was evaluated from axial sections of restorations with silicone materials representing the marginal and axial gaps. Axial and marginal fits were measured on digital photographs of the sectioned specimens with a computer program. Two-way ANOVA was used to compare differences between abutments with 2 different antirotational features and digitizing techniques separately for the marginal and axial fits of single implant-retained crowns. A post hoc least significant difference test was used to compare digitizing techniques (α=.05). RESULTS: Significant differences in the marginal fit of single-implant-retained crowns were found among digitizing techniques (P=.011) and between antirotational features (P<.001). No significant difference in the axial fit of single-implant-retained crowns was found among digitizing techniques (P=.905) or between antirotational features (P=.075). CONCLUSIONS: Within the limitations of this in vitro study, the marginal fit of single-implant-retained crowns was affected by antirotational abutment features. Furthermore, digitizing techniques were found to play an important role in the marginal fit of single-implant-retained restorations.

The effects of pulsed electromagnetic field (PEMF) on osteoblast-like cells cultured on titanium and titanium-zirconium surfaces.

BACKGROUND: Commercially pure Ti, together with Ti Ni, Ti-6Al-4V, and Ti-6Al-7Nb alloys, are among the materials currently being used for this purpose. Titanium-zirconium (TiZr) has been developed that allows SLActive surface modification and that has comparable or better mechanical strength and improved biocompatibility compared with existing Ti alloys. Furthermore, approaches have targeted making the implant surface more hydrophilic, as with the Straumann SLActive surface, a modification of the SLA surface. PURPOSE: The aim of this study is to evaluate the effects of pulsed electromagnetic field (PEMF) to the behavior of neonatal rat calvarial osteoblast-like cells cultured on commercially pure titanium (cpTi) and titanium-zirconium alloy (TiZr) discs with hydrophilic surface properties. MATERIALS AND METHODS: Osteoblast cells were cultured on titanium and TiZr discs, and PEMF was applied. Cell proliferation rates, cell numbers, cell viability rates, alkaline phosphatase, and midkine (MK) levels were measured at 24 and 72 hours. RESULTS: At 24 hours, the number of cells was significantly higher in the TiZr group. At 72 hours, TiZr had a significantly higher number of cells when compared to SLActive, SLActive + PEMF, and machine surface + PEMF groups. At 24 hours, cell proliferation was significantly higher in the TiZr group than SLActive and TiZr + PEMF group. At 72 hours, TiZr group had higher proliferation rate than machine surface and TiZr + PEMF. Cell proliferation in the machine surface group was lower than both SLActive + PEMF and machine surface + PEMF. MK levels of PEMF-treated groups were lower than untreated groups for 72 hours. CONCLUSIONS: Our findings conclude that TiZr surfaces are similar to cpTi surfaces in terms of biocompatibility. However, PEMF application has a higher stimulative effect on cells cultured on cpTi surfaces when compared to TiZr.

Comparative assessments, meta-analysis, and recommended guidelines for reporting studies on histomorphometric bone-implant contact in humans.

PURPOSE: To evaluate factors that have an influence on histomorphometric bone-to-implant contact (BIC) of dental implants in humans. MATERIALS AND METHODS: Using inclusion/exclusion criteria, eligible studies were searched in five databases and handsearched in 11 journals. A total of 351 articles were assigned to full text analysis. The extracted data were assigned to comparative statistical assessments and meta-analysis. RESULTS: A total of 55 articles were included in the analysis. The mean BIC found in comparative assessments and meta-analysis of implants in the mandible (70.97 and 69.744 ± 3.304, respectively) was higher than those in the maxilla (53.24 and 56.692 ± 3.598; P = .000 and P = .008, respectively). The mean BIC in the anterior mandible (79.42) and maxilla (74.19) were higher than the posterior mandible (69.14) and maxilla (36.68) (P < .05). Differences were detected in BIC of commercially available implants and experimental micro-implants (P < .05). Comparative assessments and meta-analysis showed that conventionally loaded implants (75.70 and 75.786 ± 4.889, respectively) had higher BIC than unloaded (54.07 and 53.24 ± 4.971, respectively) and immediately loaded implants (58.53 and 68.831 ± 4.972; P = .000 and P = .004, respectively). CONCLUSIONS: Based upon a meta-analysis of the literature the following conclusions can be made: The BIC in the mandible is higher than the maxilla. The BIC is higher in the anterior than the posterior regions. The implant design coupled with the anatomical region affects the amount of BIC. Placement of experimental micro-implants with different surfaces in the posterior region always result in low and almost comparable BIC. The loading state and healing period seems to have an influence on BIC. Specific reporting guidelines are required to improve reporting of studies on human BIC.

Predicting bone remodeling around tissue- and bone-level dental implants used in reduced bone width.

The objective of this study was to predict time-dependent bone remodeling around tissue- and bone-level dental implants used in patients with reduced bone width. The remodeling of bone around titanium tissue-level, and titanium and titanium-zirconium alloy bone-level implants was studied under 100 N oblique load for one month by implementing the Stanford theory into three-dimensional finite element models. Maximum principal stress, minimum principal stress, and strain energy density in peri-implant bone and displacement in x- and y- axes of the implant were evaluated. Maximum and minimum principal stresses around tissue-level implant were higher than bone-level implants and both bone-level implants experienced comparable stresses. Total strain energy density in bone around titanium implants slightly decreased during the first two weeks of loading followed by a recovery, and the titanium-zirconium implant showed minor changes in the axial plane. Total strain energy density changes in the loading and contralateral sides were higher in tissue-level implant than other implants in the cortical bone at the horizontal plane. The displacement values of the implants were almost constant over time. Tissue-level implants were associated with higher stresses than bone-level implants. The time-dependent biomechanical outcome of titanium-zirconium alloy bone-level implant was comparable to the titanium implant.

Early-loaded one-stage implants retaining mandibular overdentures by two different mechanisms: 5-year results.

PURPOSE: To compare the biologic and prosthetic outcomes of implants loaded early to retain mandibular overdentures by means of two different attachment systems. MATERIALS AND METHODS: Patients were screened according to specific inclusion/exclusion criteria and randomly allocated to treatment groups involving two-implant-supported early loaded mandibular overdentures retained by ball attachments or Locator attachments. Marginal bone loss, Plaque Index, peri-implant infection, Bleeding Index, prosthetic complications, and Kaplan-Meier survival estimates of the groups were assessed at the 5-year recall. RESULTS: Among the 29 patients (58 implants) who completed the study, one implant was lost during healing; all implants survived after prosthesis delivery. Bone loss in the ball attachment group (0.77 ± 0.05 mm) was significantly greater than that in the Locator group (0.59 ± 0.03 mm). The Plaque and Bleeding indices of both groups were comparable, and peri-implant inflammation scores in both groups were zero for all implants. The frequencies of activation of the matrix, replacement of the matrix, and denture reline in the ball attachment group were significantly higher than those observed in the Locator group. While assessments for the absence of any complication showed that the 1- and 3-year Kaplan-Meier survival probabilities of both groups were comparable, when activation of the retainer was excluded, survival probabilities of the ball attachment group were higher. CONCLUSIONS: The biologic outcomes of early loaded mandibular overdentures retained by ball attachments or Locators were comparable. Although the frequency of prosthetic complications with ball attachments was higher, this did not decrease the survival probability for the treatment.

A prospective, open-ended, single-cohort clinical trial on early loaded Titanium-zirconia alloy implants in partially edentulous patients: up-to-24-month results.

PURPOSE: To evaluate biologic and prosthetic outcomes of titanium-zirconia alloy implants supporting fixed prostheses. MATERIALS AND METHODS: A total of 52 titanium-zirconia alloy implants were placed in 23 consecutive patients with partial edentulism. All implants were subjected to an early loading protocol by means of single-unit or up-to-four-unit fixed partial prostheses and observed between 7 and 24 months. The radiographic marginal bone loss and peri-implant soft tissue scores (Plaque Index, Bleeding Index, and Calculus Index) were recorded. In addition, prosthetic complications were recorded during the period of the study. RESULTS: Early or late implant failures were not observed, resulting in 100% implant survival and success of the implants. No prosthetic complications were observed. The mean (standard deviation) of marginal bone loss for 52 implants was 0.315 mm (0.24 mm). There were no signs of excessive bone loss with or without swelling or suppuration of the peri-implant soft tissue, and the soft tissue scores indicated good soft tissue integration. CONCLUSIONS: Titanium-zirconia alloy implants supporting fixed prostheses showed optimum radiographic, clinical, and prosthetic outcomes in an up-to-24-month assessment period.

Immediate versus conventional loading of implant-supported maxillary overdentures: a finite element stress analysis.

PURPOSE: To compare biomechanical outcomes of immediately and conventionally loaded bar-retained implant-supported maxillary overdentures using finite element stress analysis. MATERIALS AND METHODS: Finite element models were created to replicate the spatial positioning of four 4.1 × 12-mm implants in the completely edentulous maxillae of four cadavers to support bar-retained overdentures with 7-mm distal extension cantilevers. To simulate the bone-implant interface of immediately loaded implants, a contact situation was defined at the interface; conventional loading was simulated by "bonding" the implants to the surrounding bone. The prostheses were loaded with 100 N in the projected molar regions bilaterally, and strain magnitudes were measured at the buccal aspect of bone. RESULTS: The amplitude of axial and lateral strains, the overall strain magnitudes, and the strain magnitudes around anterior and posterior implants in the immediate loading group were comparable to those seen in the conventional loading group, suggesting that the loading regimens created similar stress/strain fields (P > .05). CONCLUSIONS: Conventional and immediate loading of maxillary implants supporting bar-retained overdentures resulted in similar bone strains.

Low-level laser therapy vs. pulsed electromagnetic field on neonatal rat calvarial osteoblast-like cells.

To compare the effects of pulsed electromagnetic field (PEMF) and low-level laser therapy (LLLT) on osteoblast cells in a cell culture model. Fifty thousand neonatal rat calvarial osteoblast-like cells per milliliter were seeded and 0.06 mT PEMF, 0.2 mT PEMF, and LLLT at 808 nm were applied for 24 and 96 h on the cells. To evaluate cellular proliferation and differentiation, specimens were examined for DNA synthesis, alkaline phosphatase (ALP) activity, cell numbers, and viability of the cells. Morphological appearances of the cells were observed using scanning electron microcopy after 24 and 96 h of incubation. At 24 and 96 h, the control group had a higher cell proliferation than 0.06 and 0.2 mT PEMF groups (p=0.001). At 96 h, 0.2 mT PEMF group had higher cell proliferation rate than 0.06 mT PEMF and LLLT groups (p=0.001). The cell count and cell viability in 0.2 mT PEMF group were higher than the 0.06-mT PEMF and LLLT groups, although these differences were not statistically significant at 96 h (p>0.05). At 24 and 96 h, cell viability in the control group was higher than the test groups. Alkaline phosphatase levels of the groups were comparable in both time intervals (p>0.05). 0.2 mT PEMF application on osteoblast-like cells led to cell proliferation and differentiation better than 0.06 mT PEMF and LLLT at 808 nm, although a remarkable effect of both PEMF and LLLT could not be detected. The ALP activity of 0.2 and 0.06 mT PEMF and LLLT were comparable.

Efficacy of resonance frequency analysis in the diagnosis of compromised bone-implant interface.

PURPOSE: To investigate the sensitivity level of resonance frequency analysis (RFA) in the identification of contact loss at compromised bone-implant interfaces. METHODS: Twelve cylindrical acrylic experimental models housing a perpendicularly positioned dental implant were generated. Two different compromised bone-implant interfaces to simulate the loss of bone-to-implant contact were created in 8 models, whereas the resting 4 simulated the intact relationship between implant and bone. Each implant received RFA and subjected to serial sectioning to evaluate bone-acrylic interface microscopically. Implant stability quotient values were statistically compared among groups. Correlation level between the implant stability quotient values and bone-acrylic interface conditions was assessed. RESULTS: RFA was not sensitive to recognize the lack of horizontal contact (approximately 0.276 mm), but it was able be to discriminate the additional loss of approximately 0.1 mm at the bone-implant interface. CONCLUSION: RFA is not a reliable method in the assessment of the initial contact loss at bone-implant interface.

Fatigue resistance of 2 different CAD/CAM glass-ceramic materials used for single-tooth implant crowns.

PURPOSE: To evaluate the fatigue resistance of 2 different CAD/CAM in-office monoceramic materials with single-tooth implant-supported crowns in functional area. MATERIALS AND METHODS: A metal experimental model with a dental implant was designed to receive in-office CAD/CAM-generated monoceramic crowns. Laterally positioned axial dynamic loading of 300 N at 2 Hz was applied to implant-supported crowns machined from 2 different glass materials for 100,000 cycle. Failures in terms of fracture, crack formation, and chipping were macroscopically recorded and microscopically evaluated. RESULTS: Four of 10 aluminasilicate glass-ceramic crowns fractured at early loading cycles, the rest completed loading with a visible crack formation. Crack formation was recorded for 2 of 10 leucite glass-ceramic crowns. Others completed test without visible damage but fractured upon removal. DISCUSSION: Lack in chemical adhesion between titanium abutment and dental cement likely reduces the fatigue resistance of machinable glass-ceramic materials. However, relatively better fractural strength of leucite glass-ceramics could be taken into consideration. Accordingly, progress on developmental changes in filler composition of glass-ceramics may be promising. CONCLUSION: Machinable glass-ceramics do not possess sufficient fatigue resistance for single-tooth implant crowns in functional area.

A randomized controlled clinical trial of feldspathic versus glass-infiltrated alumina all-ceramic crowns: a 3-year follow-up.

PURPOSE: The aim of this randomized controlled clinical trial was to compare the outcome of feldspathic porcelain (group 1) and glass-infiltrated alumina all-ceramic (group 2) crowns. MATERIALS AND METHODS: Patients were recruited based on inclusion/exclusion criteria, and 33 eligible subjects were assigned randomly to one of the two treatment groups. One hundred one crowns were placed predominantly in the anterior portion of the mouth and were cemented using resin cement. A baseline California Dental Association quality evaluation was completed, and Plaque and Gingival Index scores were recorded. Prosthetic and soft tissue scores were recorded for up to 3 years. RESULTS: Five restorations experienced mechanical failure. Kaplan-Meier analysis showed that the 3-year survival probabilities for group 1 (0.94) and group 2 (0.95) restorations were comparable (P = .484). Plaque and Gingival Index scores for both groups were similar at the 3-year recall (P > .999). Marginal integrity, anatomical form, and color and surface scores were also similar for both groups (P > .05). CONCLUSION: Feldspathic and glass-infiltrated alumina all-ceramic crowns placed predominantly in the anterior portion have comparable biologic and prosthetic outcomes, as well as survival probabilities.

Spontaneous early exposure and marginal bone loss around conventionally and early-placed submerged implants: a double-blind study.

PURPOSE: The aim of this retrospective study was to compare the frequency of spontaneous early exposure of cover screws and marginal bone resorption in conventionally and early-placed submerged implants before second-stage surgery. MATERIALS AND METHODS: A total of 103 Nobel Biocare Branemark implants were conventionally (Group 1), or early-placed (Group 2) in 46 consecutive patients following the two-stage surgical protocol. Patients in both groups received oral hygiene training in self-performed plaque control measures, including exposure of cover screws during healing. Spontaneous cover screw exposure (CSE) of each implant was recorded for both groups and scored from Class 0 (no perforation) to Class 4 (complete exposure). Plaque index scores were recorded and marginal bone-level (MBL) changes were measured in radiographs before second-stage surgery in a blind manner. RESULTS: MBL in Group 2 was higher than Group 1 in patients with or without interim prosthesis (P<0.05). The use of interim prosthesis did not increase MBL in Group 1, but led to higher MBL in Group 2. The percentage of non-exposed implants in Group 1 was higher than Group 2 (P=0.007, odds ratio=7). Group 1 implants had 11.5 times greater plaque index score 0 than those in Group 2 (P=0.031, odds ratio=11.5). The differences between MBL with regard to CSE scores 0 and 1-4 was significant for both sides in Group 2 and the mesial side in Group 1 (P<0.05). The difference between MBL with regard to plaque index scores 1-3 was similar in both groups (P>0.05). CONCLUSIONS: There is a direct relation between spontaneous early cover screw perforations with early crestal bone loss. Early-placed implants experienced more spontaneous perforations and associated bone loss in comparison with conventionally placed submerged implants. The use of interim dentures may lead to more CSE and consequent MBL in the early-placement protocol.

A systematic review of marginal bone loss around implants retaining or supporting overdentures.

PURPOSE: To evaluate, through a systematic review of the literature, the effects of implant design and attachment type on marginal bone loss in implant-retained/supported overdentures. MATERIALS AND METHODS: With the combined search terms "implant and overdenture," "implant-supported overdenture," "implant-retained overdenture," and "implant-anchored overdenture," along with specific inclusion and exclusion criteria, eligible articles between 1997 and 2008 (up to April 1) were retrieved from PubMed, EMBASE, OVID, the Cochrane Library databases, and seven journals by hand searching. Marginal bone loss values with regard to time, attachment type, and implant system used were compared by Kruskal-Wallis tests. Means and standard deviations of data were combined using fixed- and random-effect models and evaluated using meta-analysis. RESULTS: Forty-six articles were included in the analyses; data extraction and meta-analysis were able to be conducted on eight studies. Data regarding maxillary overdentures could not be analyzed statistically. Bone loss around mandibular implants did not seem to be influenced by implant system or attachment design (bar, ball, magnet, and other types) in the first year, from 1 to = or < 5 years, and even after 5 years (P > .05). Meta-analysis could not detect differences in implant systems or attachment types (P > .05). CONCLUSIONS: Based upon a systematic review and meta-analysis of the literature that identified a total of 4,200 implants from 13 manufacturers, there was no difference in marginal bone loss around implants retaining/supporting mandibular overdentures relative to implant type or attachment designs.

Marginal bone level changes and prosthetic maintenance of mandibular overdentures supported by 2 implants: a 5-year randomized clinical trial.

BACKGROUND: Documentation of early loading of mandibular overdentures supported by different implant systems is scarce. PURPOSE: This study aimed to compare the biologic and prosthetic outcome of mandibular overdentures supported by unsplinted early-loaded one- and two-stage oral implants after 5 years of function. MATERIALS AND METHODS: Twenty-eight consecutive patients were screened following an inclusion and exclusion criteria, and randomly allocated to treatment groups. Ball-retained mandibular overdentures were fabricated on two unsplinted Straumann (Institut Straumann AG, Basel, Switzerland) and Brånemark (Nobel Biocare AB, Göteborg, Sweden) dental implants and subjected to an early-loading protocol. During the 5-year period, prosthetic complications were recorded. At 5-years of function, plaque, peri-implant inflammation, bleeding, and calculus index scores were recorded, and standard periapical radiographs were obtained from each implant for measurement of marginal bone loss. RESULTS: All implants survived during the observation period. The peri-implant inflammation, bleeding, and calculus index scores around Straumann and Brånemark implants were similar (p > .05). The marginal bone loss around Brånemark implants (1.21 +/- 0.1) was higher than Straumann implants (0.73 +/- 0.06) at 5 years of function (p = .002). Kaplan-Meier tests revealed that 1- and 5-year survival of overdentures on Straumann and Brånemark implants were similar (p = .85). Wear of the ball abutment in the Brånemark group was higher than in the Straumann group (p < .05). Complications regarding the retainer and the need for occlusal adjustments were higher in the Straumann group (p < .05). Chi-square test revealed that the frequency of retightening of the retainer was higher in the Straumann group than in the Brånemark group (p < .05). CONCLUSIONS: Mandibular overdentures supported by unsplinted early-loaded Straumann and Brånemark implants lead to similar peri-implant soft tissue and prosthetic outcomes, although higher marginal bone loss could be observed around Brånemark implants after 5 years.

Numerical simulation of the effect of time-to-loading on peri-implant bone.

PURPOSE: To evaluate the effect of time-to-loading on trabecular bone around single-tooth dental implants using numerical solutions based on computer models. MATERIALS AND METHODS: A global model with a coarse mesh carrying a Straumann dental implant (043.033S; Institut Straumann, Basel, Switzerland) was created. A region of interest in trabecular bone was defined to study a localized part of the global model with a refined mesh. Time-to-loading submodels to simulate 2h, 4 days, 1, 4, 6 and 12 wks of trabecular bone-healing status were designed and created. Bone types were considered in the simulation by different elastic bone properties. A 100-N oblique static load was applied. Maximum and minimum principal stresses were calculated and visualized. RESULTS: Bone types with higher elastic moduli experienced higher stress levels. Changes in the quality and quantity of bone at the bone-implant interface did not affect the overall stress distribution. Peri-implant bone with a higher elastic modulus preserved the stress increase at the implant-bone interface. DISCUSSION: Reduced bone contact may not have a prevailing effect over bone quality and quantity on stress generation at the peri-implant bone. CONCLUSION: Time-to-loading of single-tooth implants may not differ in terms of load distributions in neighboring peri-implant bone.

Predicting time-dependent remodeling of bone around immediately loaded dental implants with different designs.

The purpose of this study was to predict time-dependent biomechanics of bone around cylindrical screw dental implants with different macrogeometric designs under simulated immediate loading condition. The remodeling of bone around a parallel-sided and a tapered dental implant of same length was studied under 100N oblique load by implementing the Stanford theory into three-dimensional finite element models. The results of the analyses were examined in five time intervals consisting loading immediately after implant placement, and after 1, 2, 3 and 4 weeks following implantation. Maximum principal stress, minimum principal stress, and strain energy density in peri-implant bone and displacement in x-(implant lateral direction with a projection of the oblique force) and y-(implant longitudinal direction) axes of the implant were evaluated. The highest value of the maximum and minimum principal stresses around both implants increased in cortical bone and decreased in trabecular bone. The maximum and minimum principal stresses in cortical bone were higher around the tapered cylindrical implant, but stresses in the trabecular bone were higher around the parallel-sided cylindrical implant. Strain energy density around both implants increased in cortical bone, slightly decreased in trabecular bone, and higher values were obtained for the parallel-sided cylindrical implant. Displacement values slightly decreased in time in x-axis, and an initial decrease followed by a slight increase was observed in the y-axis. Bone responded differently in remodeling for the two implant designs under immediate loading, where the cortical bone carried the highest load. Application of oblique loading resulted in increase of stiffness in the peri-implant bone.