Perception of Heart Attack Risk Factors and Their Complications Among the Adult Population in the Eastern Region of Saudi Arabia.

Background Among the young population, many have risk factors that are nonmodifiable, modifiable, or both, increasing their chances of developing cardiovascular diseases (CVDs) and/or experiencing a heart attack later in life. Knowledge of both risk factors has a major role in preventing CVD by encouraging screening and applying the necessary lifestyle modifications. This study aims to assess the knowledge of risk factors and complications associated with heart attacks among individuals in the early adulthood age group. Methodology This descriptive cross-sectional study encompassed residents of the Eastern Region who met the specified inclusion criteria. Data were collected and recorded on a structured questionnaire regarding their demographic information, current risk factors, and knowledge of cardiovascular risk factors and complications. The questionnaire was distributed in hard copy among schools, colleges, and primary healthcare centers. The statistical analysis was carried out using IBM SPSS Statistics for Windows, Version 26.0 (IBM Corp., Armonk, NY). The results were presented in tables as percentages and frequencies for all variables, and the scores were presented as mean and standard deviation.  Results Among the 334 participants, the average overall score was 15.47 out of 28. The participants exhibited varying levels of knowledge across different aspects of the risk factors. The correct response rate ranged from as high as 84.4% (282) to as low as 41.6% (139) in the assessment of risk factors items. The majority of the participants showed a good understanding of the preventive measures, such as exercise and weight reduction. However, 43.4% (145) of participants reported not participating in physical activity and 29.1% (97) had a body mass index of 25 and above. Conclusions The outcome of this study suggests that there's a need for structured educational programs in schools and public health campaigns. The general public must have a reliable source of information rather than the mass media and false information read from social media.

Clinical outcome of pre-operative blood transfusion for sickle cell disease patients in post-operative complications.

BACKGROUND: Preoperative blood transfusion for patients with sickle cell disease is a debatable topic and it can be lifesaving. Sickle cell disease patients are at high risk for vaso-occlusive crisis due to the large concentration of sickle hemoglobin (HgbS) in their blood. Despite the current extensive research into this disease, there is still no consensus over whether blood transfusion is a preferable preoperative modality among patients undergoing elective surgical procedures. METHOD: A retrospective observational study, which enrolled 204 patients with Sickle cell disease who underwent surgery at King Fahad Hospital of the University (KFHU) over the last five years. The primary objective was to determine whether there is evidence that preoperative blood transfusion for SCD patients undergoing surgical procedures will reduce postoperative complications related to SCD. RESULTS: A total of 204 patients were included, of which 30% had preoperative blood transfusion. Majority of patient 44% had undergone cholecystectomy. On multivariate logistic regression analysis, patients who did not undergo blood transfusion had significantly higher risk to develop post-operative SCD complications (OR = 3.07, P value = 0.002). In addition, they had significantly prolonged hospitalization (OR = 2.22, P value = 0.08). In contrast, patients who received blood transfusion had lower risk for developing post-operative SCD-related complications (OR = 1.87, P value = 0.29), and decrease in the duration of hospitalization by (OR = 0.49, P value = 0.045). CONCLUSION: Our study showed that patients who had not undergone preoperative blood transfusion had higher risk to develop postoperative complications and prolonged hospital stay compared to those who underwent blood transfusion.

The Association of Blood Glucose Levels and Arterial Stiffness (Cardio-Ankle Vascular Index) in Patients With Type 2 Diabetes Mellitus.

INTRODUCTION:  Diabetes mellitus causes a major burden on healthcare systems all around the world. It has been documented that type 2 diabetes mellitus (T2DM) is associated with long-term vascular complications including micro-vascular, macro-vascular, and mixed-vascular disorders. Several studies have concluded that the increment of arterial wall stiffness is correlated with an increase in the risk of cardiovascular adverse events and the mortality associated with it. AIMS:  This study purposed to evaluate the arterial stiffness measurements, using Cardio-Ankle Vascular Index (CAVI), in T2DM patients, and the relationship with the fasting blood glucose (FBG), hemoglobin A1c (HbA1c), and other factors that may increase the risk of elevated arterial stiffness in T2DM patients. METHODOLOGY:  A total of 200 patients were recruited from the outpatient setting at King Fahd Hospital of the University, Al Khobar. A total of 181 patients fit the inclusion criteria. The charts of the patients who fit the inclusion criteria were reviewed and data related to age, gender, body mass index, smoking history, FBG, HbA1c levels, blood pressure (mmHg) measurements, and CAVI scores were collected. RESULTS:  The elevation in CAVI readings was noted to be more prominent in the senior age group. Hypertensive patients also showed a significant increase in CAVI readings. In addition, higher CAVI readings were more associated with the male gender rather than females. All of which showed a significant correlation. Furthermore, although it was not significant, higher FBG levels and HbA1c readings were correlated with higher CAVI readings. CONCLUSION:  The results of the study suggest that factors like age, smoking status, gender, and the increase in blood pressure as well as the increase in blood glucose levels are correlated with higher CAVI readings in T2DM patients. This demonstrates their important effect on arterial wall stiffness while showing that CAVI can be used in predicting the prognosis of arterial wall health in patients with diabetes.