Abundance and Seasonality of Aedes aegypti (Diptera: Culicidae) in Two Suburban Localities of South Mexico, With Implications for Wolbachia (Rickettsiales: Rickettsiaceae)-Carrying Male Releases for Population Suppression.

We conducted a baseline characterization of the abundance and seasonality of Aedes aegypti (Linnaeus, 1762)-a vector of dengue, chikungunya, and Zika-in two suburban localities of Yucatan, Mexico, as the first step in the implementation of an integrated vector management (IVM) plan combining 'traditional Aedes control' (source reduction/truck-mounted ultra-low volume [ULV] spraying) and incompatible insect technique/sterile insect technique for population suppression in Yucatan, Mexico. Weekly entomological collections with ovitraps and BG-sentinel traps were performed in 1-ha quadrants of both localities for 1 yr. Three distinct periods/phases were identified, closely associated with precipitation: 1) a phase of low population abundance during the dry season (weekly average of Aedes eggs per ovitrap and adults per BG trap = 15.51 ± 0.71 and 10.07 ± 0.88, respectively); 2) a phase of population growth and greatest abundance of Aedes (49.03 ± 1.48 eggs and 25.69 ± 1.31 adults) during the rainy season; and finally 3) a phase of decline among populations (20.91 ± 0.97 eggs and 3.24 ± 0.21 adults) after the peak of the rainy season. Seasonal abundance and dynamics of Ae. aegypti populations suggest that it is feasible to develop and implement time-specific actions as part of an IVM approach incorporating integrating novel technologies (such as rear-and-release of Wolbachia-infected males) with classic (insecticide-based) approaches implemented routinely for vector control. In agreement with the local vector control program, we propose a pilot IVM strategy structured in a preparation phase, an attack phase with traditional vector control, and a suppression phase with inundative releases, which are described in this paper.

Predicting Recreational Runners' Marathon Performance Time During Their Training Preparation.

ABSTRACT: Esteve-Lanao, J, Del Rosso, S, Larumbe-Zabala, E, Cardona, C, Alcocer-Gamboa, A, and Boullosa, DA. Predicting marathon performance time throughout the training preparation in recreational runners. J Strength Cond Res 35(11): 3218-3224, 2021-The objective of this study was to predict marathon performance at different time points along the season using different speeds derived from ventilatory thresholds and running economy (RE). Sixteen recreational runners (8 women and 8 men) completed a 16-week marathon training macrocycle. Aerobic threshold (AeT), anaerobic threshold (AnT), and maximal oxygen uptake were assessed at the beginning of the season, whereas speeds eliciting training zones at AeT and AnT, and RE were evaluated at 5-time points during the season (M1-M5). Analyses of variance and hierarchical regression analyses were conducted. Training improved AeT and AnT speeds at M2 vs. M1 (p = 0.001) and remained significantly higher at M3, M4, and M5 (p = 0.001). There was a significant effect of time (p = 0.003) for RE, being higher at M4 and M5 compared with M1 and M3. Significant correlations were found between marathon performance and speeds at AeT and AnT at every time point (r = 0.81-0.94; p < 0.05). Speed at AnT represented the main influence (65.9 and 71.41%) in the final time prediction at M1 and M2, whereas speed at AeT took its place toward the end of the macrocycle (76.0, 80.4, and 85.0% for M3, M4, and M5, respectively). In conclusion, assessment of speeds at AeT and AnT permits for reasonable performance prediction during the training preparation, therefore avoiding maximal testing while monitoring 2 fundamental training speeds. Future research should verify if these findings are applicable to runners of different levels and other periodization models.

Genetic variation of FTO: rs1421085 T>C, rs8057044 G>A, rs9939609 T>A, and copy number (CNV) in Mexican Mayan school-aged children with obesity/overweight and with normal weight.

OBJECTIVES: Genetic variation of the fat mass and obesity associated gene (FTO) has been identified as a risk factor for obesity and obesity traits. Distribution of FTO single nutleotide polymorphisms (SNPs) rs1421085T>C, rs9939609T>A, rs8057044G>A and copy number variation (CNV) was evaluated in association with childhood obesity or overweight status in children with Mayan ethnicity. METHODS: We included 318 school-aged children with obesity or overweight status (body mass index [BMI]: >85th percentile) and 303 children with normal weight (BMI: 15th-85th percentile). Genotyping was performed using real-time polymerase chain reaction (RT-PCR) with TaqMan probes. The cross-sectional study was carried out using univariate and multivariate logistic regression models adjusted for gender. RESULTS: FTO-SNP rs1421085 showed significant differences between children with obesity and children with normal weight for the heterozygous genotype (P = 0.003) and for allele frequencies (P = 0.023). Adjusting by gender, significant differences were found in frequencies of the hetezygous genotype of SNPs rs9939609 (P = 0.023) and rs1421085 (P = 0.003) as well as in allele frequencies (P = 0.042 and P = 0.013, respectively) between girls with obesity and girls without obesity. In contrast, SNP rs8057044 was significantly different only between heterozygous overweight versus normal weight boys (P = 0.035) and for the allele frequency of rs8057044 (P = 0.021). The mean relative CNV was significantly higher in male overweight children than in boys with normal weight (P = 0.000). CONCLUSIONS: The FTO SNP rs1421085 is a genetic factor associated with obesity in Mayan school-aged children. FTO SNPs rs1421085 and rs9939609 affect genetic susceptibility for obesity only in girls, whereas, SNP rs8057044 and CNV are associated with overweight status only in boys.

Nutrimetry: BMI assessment as a function of development. / Nutrimetría: evaluando el IMC en función del desarrollo.

BACKGROUND AND OBJECTIVE: Adequate nutritional assessment is required to fight malnutrition (undernutrition and overfeeding) in children and adolescents. For this, joint interpretation of certain indicators (body mass index [BMI], height, weight, etc.) is recommended. This is done clinically, but not epidemiologically. The aim of this paper is to present "nutrimetry", a simple method that crosses anthropometric information allowing for bivariate interpretation at both levels (clinical and epidemiological). MATERIALS AND METHODS: Data from 41,001 children and adolescents aged 0-19 years, taken from Mexico's National Health and Nutrition Survey 2012, were analyzed. Data crossed were BMI-for-age z-scores (BAZ) with height-for-age z-scores (HAZ) according to the World Health Organization (WHO) standards. Conditional prevalences were calculated in a 3×3 grid and were compared with expected values. RESULTS: This method identified subgroups in each BAZ category showing heterogeneity of the sample with regard to WHO standards for HAZ and nutritional status. According to the method, nutritional status patterns differed among Mexican states and age and sex groups. CONCLUSION: Nutrimetry is a helpful and accessible tool to be used in epidemiology. It allows for detecting unexpected distributions of conditional prevalences, its graphical representation facilitates communication of results by geographic areas, and enriched interpretation of BAZ helps guide intervention actions according to their codes.

Metabolic, cardiorespiratory, and neuromuscular fitness performance in children with cerebral palsy: A comparison with healthy youth.

The aim of this study was to assess metabolic, cardiorespiratory, and neuromuscular fitness parameters in children with spastic cerebral palsy (CP) and to compare these findings with typically developing children. 40 children with CP (21 males, 19 females; mean age, 11.0±3.3 yr; range, 6.5-17.1 yr; Gross Motor Function Classification System levels 1 or 2) and 40 healthy, age- and sex-matched children completed a test battery that consisted of 8 tests and 28 measures that assessed cardio-respiratory fitness, energy expenditure, anaerobic endurance, muscle strength, agility, stability and flexibility. Children with CP had significantly lower performance (P<0.05) on most cardiorespiratory and metabolic tests than those of healthy children, Differences in neuromuscular measures of muscular strength, speed, agility, anaerobic endurance, and flexibility between groups were most apparent. Grouped differences in cardiorespiratory variables revealed a 25% difference in performance, whereas grouped differences in metabolic and neuromuscular measures were 43% and 60%, respectively. The physical fitness of contemporary children with CP is significantly less than healthy, age-matched children. Significant differences in neuromuscular measures between groups can aid in the identification of specific fitness abilities in need of improvement in this population.

Running world cross-country championships: a unique model for pacing.

UNLABELLED: The aim of this study was to describe the pacing distribution during 6 editions of the world cross-country championships. METHODS: Data from the 768 male runners participating from 2007 to 2013 were considered for this study. Blocks of 10 participants according to final position (eg, 1st to 10th, 11 to 20th, etc) were considered. RESULTS: Taking data from all editions together, the effect of years was found to be significant (F(5,266) = 3078.69, P < .001, ω² = 0.31), as well as the effect of blocks of runners by final position (F(4,266) = 957.62, P < .001, ω² = 0.08). A significant general decrease in speed by lap was also found (F(5,1330) = 2344.02, P < .001, ω² = 0.29). Post hoc analyses were conducted for every edition where several pacing patterns were found. All correlations between the lap times and the total time were significant. However, each lap might show different predicting capacity over the individual outcome. DISCUSSION: Top athletes seem to display different strategies, which allow them to sustain an optimal speed and/or kick as needed during the critical moments and succeed. After the first group (block) of runners, subsequent blocks always displayed a positive pacing pattern (fast to slow speed). Consequently, a much more stable pacing pattern should be considered to maximize final position. CONCLUSIONS: Top-10 finishers in the world cross-country championships tend to display a more even pace than the rest of the finishers, whose general behavior shows a positive (fast-to-slow) pattern.